首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   11185篇
  免费   557篇
  国内免费   638篇
系统科学   569篇
丛书文集   318篇
教育与普及   206篇
理论与方法论   64篇
现状及发展   58篇
研究方法   39篇
综合类   11123篇
自然研究   3篇
  2024年   21篇
  2023年   112篇
  2022年   226篇
  2021年   222篇
  2020年   174篇
  2019年   101篇
  2018年   148篇
  2017年   185篇
  2016年   176篇
  2015年   371篇
  2014年   431篇
  2013年   471篇
  2012年   511篇
  2011年   565篇
  2010年   490篇
  2009年   564篇
  2008年   601篇
  2007年   549篇
  2006年   510篇
  2005年   468篇
  2004年   419篇
  2003年   388篇
  2002年   525篇
  2001年   498篇
  2000年   356篇
  1999年   501篇
  1998年   372篇
  1997年   364篇
  1996年   285篇
  1995年   274篇
  1994年   267篇
  1993年   191篇
  1992年   225篇
  1991年   184篇
  1990年   166篇
  1989年   168篇
  1988年   134篇
  1987年   97篇
  1986年   47篇
  1985年   21篇
  1984年   1篇
  1980年   1篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
主要利用微分包含的方法得到模糊微分方程的反周期解的存在性结果,并给了一个例子说明主要结果的可行性.  相似文献   
2.
基于行为金融学的价格压力假说,结合企业生命周期理论,以2007—2014年的主板上市公司为样本,分析投资者关注对权益资本成本的影响以及这种影响在企业生命周期中存在的阶段性差异。研究发现,投资者关注与权益资本成本显著负相关,即权益资本成本随着投资者关注的提高而降低。对于不同生命周期的企业,投资者关注对权益资本成本的影响存在差异。新生期、衰退期企业的权益资本成本并不会随着投资者关注程度的提高而降低;成长期、成熟期企业的权益资本成本随着投资者关注程度的提高而降低。可以看出,投资者能够识别企业所处的生命周期,并愿意为成长期、成熟期的企业支付更高的溢价。  相似文献   
3.
为研究干湿循环和吸力共同作用对非饱和下蜀土力学特性的影响,选取镇江某边坡的下蜀土为研究对象,通过非饱和直剪试验,对不同干湿循环次数及吸力水平下下蜀土力学特性的变化规律进行了研究.结果 表明:随着干湿循环次数的增加,下蜀土表面裂隙明显增加并具有不可逆性;下蜀土的抗剪强度经短暂增大后逐渐降低,并在第4次干湿循环作用后趋于稳定;下蜀土的黏聚力在经历短暂提高后逐渐降低并趋于稳定,而其内摩擦角则随干湿循环次数的增加变化幅度较小,呈上下波动态势;相同干湿循环次数下,吸力的存在对于下蜀土的黏聚力具有提升作用,而对土体内摩擦角的影响则不明显.研究结果可为干湿循环作用下下蜀土边坡的稳定性分析提供计算参数,具有实际工程意义.  相似文献   
4.
5.
为了优化自密实高流态混凝土配合比,提高混凝土工作和力学性能,分别以胶凝材料、砂率和外加剂组分为关键变量,采用单一控制变量法,通过改变材料组分掺合量探究对自密实高流态混凝土性能影响.结果 表明:当胶凝材料在500~530kg/m3时,有较高流动性;超过530kg/m3时,间隙通过性效果好;低于530kg/m3时,可降低离析率.砂率为48%~50%时,拌合物流动性、间隙通过性较稳定,继续增大,抗离析性效果欠佳.当外加剂增大,流动性增加而抗离析性降低,外加剂为1.0%~1.2%时,对间隙通过性影响较小,与流动性、抗离析性较统一.随胶凝材料、砂率和外加剂各自增大,胶凝材料对3d、7d和28d抗压强度均有影响,砂率对3d抗压强度影响显著,外加剂对28d抗压强度影响明显.  相似文献   
6.
(CoCrFeNi)95Nb5 high entropy alloy(HEA)coatings were successfully fabricated on a substrate of Q235 steel by laser cladding technology.These(CoCrFeNi)95Nb5 HEA coatings possess excellent properties,particularly corrosion resistance,which is clearly superior to that of some typical bulk HEA and common engineering alloys.In order to obtain appropriate laser cladding preparation process parameters,the effects of laser energy density on the microstructure,microhardness,and corrosion resistance of(CoCrFeNi)95Nb5 HEA coating were closely studied.Results showed that as the laser energy density increases,precipitation of the Laves phase in(CoCrFeNi)95Nb5 HEA coating gradually decreases,and diffusion of the Fe element in the substrate intensifies,affecting the integrity of the(CoCrFeNi)95Nb5 HEA.This decreases the microhardness of(CoCrFeNi)95Nb5 HEA coatings.Moreover,the relative content of Cr2O3,Cr(OH)3,and Nb2O5 in the surface passive film of the coating decreases with increasing energy density,causing corrosion resistance to decrease.This study demonstrates the controllability of a high-performance HEA coating using laser cladding technology,which has significance for the laser cladding preparation of other CoCrFeNi-system HEA coatings.  相似文献   
7.
受相控阵天线指向误差和天线罩瞄准误差的共同影响,相控阵雷达导引头存在较严重的指向误差。当指向误差斜率超出一定范围时会造成导弹制导系统出现寄生回路振荡问题,影响系统的稳定性和制导精度,在高空尤为明显。对此,本文通过构建相控阵雷达导引头制导系统模型,分析了导引头指向误差斜率对导弹制导的影响以及产生寄生回路振荡的机理;为消除导引头指向误差斜率对制导的不利影响,在指向误差测量补偿的基础上,又给出了一种多模型扩展卡尔曼滤波的估计方法,对导引头指向误差斜率进行实时估计与补偿。数字仿真结果表明,所提方法能够有效改善导引头指向误差斜率对制导系统的不利影响,提高系统稳定性和制导精度。  相似文献   
8.
An innovative method for recovering valuable elements from vanadium-bearing titanomagnetite is proposed. This method involves two procedures: low-temperature roasting of vanadium-bearing titanomagnetite and water leaching of roasting slag. During the roasting process, the reduction of iron oxides to metallic iron, the sodium oxidation of vanadium oxides to water-soluble sodium vanadate, and the smelting separation of metallic iron and slag were accomplished simultaneously. Optimal roasting conditions for iron/slag separation were achieved with a mixture thickness of 42.5 mm, a roasting temperature of 1200°C, a residence time of 2 h, a molar ratio of C/O of 1.7, and a sodium carbonate addition of 70 wt%, as well as with the use of anthracite as a reductant. Under the optimal conditions, 93.67% iron from the raw ore was recovered in the form of iron nugget with 95.44% iron grade. After a water leaching process, 85.61% of the vanadium from the roasting slag was leached, confirming the sodium oxidation of most of the vanadium oxides to water-soluble sodium vanadate during the roasting process. The total recoveries of iron, vanadium, and titanium were 93.67%, 72.68%, and 99.72%, respectively.  相似文献   
9.

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.
  相似文献   
10.
In this paper, a life-cycle model with retirement is set up to study how an individual chooses the optimal retiring age on account of wage growth rate, longevity and healthy state. It is proved that there exists optimal retiring age under given conditions. The numerical simulations are given to show how wage growth rate, longevity and healthy state affect retiring age.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号