碱性成纤维细胞生长因子在乳腺良恶性病变细胞中的分布特征及其微血管密度的关系

目的 :研究碱性成纤维细胞生长因子 (bFGF)在乳腺癌细胞中的表达特征 ,寻找有助于诊断乳腺癌的生物学标记 .方法 :收集乳腺腺病、乳腺纤维腺瘤和乳腺癌等的手术切除标本各 2 2例 ,常规石蜡包埋切片 (4μm) ,分别做HE染色和用ABC法进行bFGF(1∶2 0 0 )、血管标记抗体CD34(1∶10 0 )免疫组织化学染色 ,参考Weidner和Maeda方法进行微血管密度 (MVD)测定 .结果 :在乳腺腺病和乳腺纤维腺瘤中的肌上皮细胞、导管上皮细胞、血管内皮细胞、血管壁平滑肌细胞和纤维母细胞等均表达bFGF ,其阳性产物主要位于胞浆 ,肌上皮细胞和导管上皮细胞的阳性产物部分见于胞核 ,但乳腺癌细胞的阳性产物主要位于胞膜 ,少数位于胞浆 ;胞核阴性 ,与良性增生性病变形成鲜明的对照 .2 2例乳腺癌bFGF膜阳性者 17例 (占 77 3% ) ,其MVD =90 5 6± 2 3 6 2 .肿瘤直径 4cm(10 /2 2例 )时 ,MVD增高达 93 19± 2 0 75 .乳腺腺病MVD =4 2 0 5± 12 2 6 ,乳腺纤维腺瘤MVD =4 3 14± 18 2 1,与乳腺癌相比有显著差异 (P <0 0 1) .结论 :1)bFGF免疫染色阳性产物在乳腺癌细胞中主要分布在胞膜 ,在良性增生性病变细胞中主要位于胞浆和胞核 .乳腺癌的MVD明显高于良性增生性病变 .2 )质量好的免疫染色、bFGF反应产物的分布特征 ,结合MVD有助于     

前臂骨间背侧神经分支规律与临床治疗对策

探讨了前臂骨间背侧神经（posterior interosseous nervus,pIN）的分支规律及其在临床对伸肌腱损伤的影响。在24例成人尸体上,通过前臂背侧切口进入,找到穿出该肌深浅头出口之间的pIN。对pIN各分支距起点的距离及pIN支配各伸肌肌支的数目等进行观测。pIN有3处主要分支点：pIN近端：pIN分支至指伸肌肌支（3±1）、尺侧腕伸肌肌支（4±1）处,距pIN出口（24±3）mm,其中指伸肌肌支28例（47%）位于近侧,32例（53%）位于远侧;pIN中端：pIN分支至指伸肌肌支（3±1）、拇短伸肌肌支（1±1）、拇长展肌肌支（2＋1）、小指伸肌肌支（2±1）处,距pIN出口（47±3）mm;pIN远端：pIN分支至拇短伸肌肌支（1±1）,拇长展肌肌支（2±1）,拇长伸肌（2±1）,示指固有伸肌（2±1）处,距pIN出口（81±3）mm。24例中23例获随访,平均随访14个月,3例pIN或其分支损伤完全恢复,最快恢复时间为2个月。pIN分支复杂但有规律可循,其不同节段的损伤产生不同的临床表现,对指导临床治疗有积极的意义。     

雉科6种雄性中央尾羽特征比较

观察雉科6种29个雄性标本,测量中央尾羽性状并统计,结果表明:6种中央尾羽色斑格局不相同;中央尾羽长、内翈宽、外翈宽都存在显著差异(P<0.05).以白腹锦鸡的中央尾羽最长(75.9±1.30)cm, 鹧鸪(7.5±0.96)cm最短;以蓝马鸡的内翈(3.89±0.59)cm和外翈(4.63±0.73)cm最宽, 鹧鸪的内翈(1.22±0.17)cm和外翈(0.97±0.14)cm最窄;这些差异有助于分辩雉科不同鸟类.     

臂部桡神经的应用解剖

目的为临床手术时提供桡神经的解剖学资料.方法在44例成人尸体上肢标本上观察臂部桡神经的行经.结果桡神经进入桡神经沟时位于胸大肌腱止端内侧(2.23±0.24)cm,喙突下方(11.21±0.42)cm.结论胸大肌腱止点纵行切开骨膜可避免损伤桡神经上段;沿骨膜向远侧分离可避免损伤桡神经中段;沿肱肌中线分开肱肌至骨膜下可避免损伤桡神经下段.     

下颌下腺移植的应用解剖研究

目的研究下颌下腺的形态学资料, 为自体下颌下腺去神经移植治疗重症干眼病手术提供相关解剖学数据.方法手术显微镜下解剖10 例双侧经颈总动脉灌注红色乳胶的正常成人头颈部标本,观测有关形态学数据.结果下颌下腺大小为：长（3.10±0.58）cm,宽（1.82±0.20）cm,厚（1.49±0.41）cm;下颌下腺内侧前端穿出下颌下腺导管,导管长（4.6±0.5）cm,管径（3.0±0.9）mm;面动脉、舌动脉与颏下动脉等都是营养下颌下腺动脉,其最重要的血供是面动脉,面静脉是下颌下腺主要回流的血管.结论本文的观察数据对施行自体下颌下腺移植术治疗重症干眼病具有一定的参考价值.     

南阳地区回族成人手足形态学与遗传学基本参数研究

目的:探讨南阳地区回族成人手足形态学与遗传学表型特征.方法:采用形态学测量身高、体重及手足5项指标,捺印法研究手部肤纹学,观察手足7项遗传表型分型,并进行统计学分析.结果:男性手长、手宽、足长、足宽、足高分别为(18.45±0.97)、(8.25±0.64)、(23.14±1.39)、(9.36±0.90)、(9.45±1.32)cm,女性为(17.23±0.81)、(7.40±0.73)、(20.46±1.30)、(8.75±0.84)、(8.64±1.17)cm.双手指纹嵴线总数男女分别为(135.06±19.87)、(125.50±20.44),atd角、t PD、a-b嵴线数分别为(15.49±6.77)、(44.61±9.11)、(34.16±5.46)、(15.53±6.46)、(43.37±9.23)、(33.73±4.07).扣手、利手、环食指长、指甲形状、拇指类型、利足、指足趾长右型率处于中等水平.结论:南阳地区回族成人手足形态学及遗传学参数大多存在性别差异和年龄差异,同时存在较大的地区差异.     

不同云南蓝果树枯落物厚度对其种子萌发影响的初探

云南蓝果树(Nyssa yunnanensis W.C.Yin)为我国热带北缘特有珍稀濒危植物,落叶大乔木,被列为国家一级保护野生树种。根据野外调查,目前云南蓝果树自然更新困难,枯枝落叶是森林更新的重要影响因素。本研究设计了种子表面覆盖0cm、1cm、2cm、3cm、4cm厚枯落物和种子置于1cm、和2cm厚枯落物表面7个实验处理,模拟自然条件研究枯落物对云南蓝果树种子萌发的影响,结果表明:不同枯枝落叶厚度处理对种子的萌发率没有显著的影响,0cm枯枝落叶厚度处理萌发率最高,为42.7%±3.7%;不同枯枝落叶厚度处理对起始萌发时间有显著的影响,枯枝落叶厚度在0cm的起始萌发时间最早,为7d。同时随着厚度的增加,萌发起始时间推迟,最迟为4cm的处理,为19d;不同枯枝落叶厚度处理对种子的发芽势也有显著影响,0cm处理时发芽势最高,为18.0%±3.8%,除0cm外的其他处理之间无显著差异。     

秦岭西坝花岗岩LA-ICP-MS 锆石 U-Pb 年代学及其地质意义

西坝花岗岩位于南秦岭构造带陕西境内, 主要由花岗闪长岩、二长花岗岩和英云闪长岩组成。LA-ICP-MS 锆石U-Pb 原位同位素定年结果表明, 西坝岩体侵位于印支期, 由二长花岗岩样品(XB01-2)得到了219±1 Ma的年龄, 花岗闪长岩样品(XB06-1) 给出的年龄是218±1 Ma, 二者在误差范围内一致, 约218Ma代表了西坝花岗岩体的成岩时代。西坝岩体的年龄结合区域构造背景以及前人研究的地球化学特征, 说明它可能是秦岭主造山期岩浆活动的产物。     

脱细胞生物敷料对烫伤创面愈合的影响

目的研究脱细胞生物敷料对小型猪深Ⅱ度烫伤创面愈合的影响。方法巴马实验用小型猪24头,雌雄不限,体质量(15±3) kg通过铜锭制备大小为4 cm×6 cm的深Ⅱ度烫伤模型,随机分为两组,试验组使用脱细胞生物敷料,空白对照组使用脱脂棉纱布。术后1、2、3、4周统计创面愈合率和愈合时间,并进行临床观察、组织病理学观察及创面羟脯氨酸含量检测,分析创面愈合情况。结果试验过程中动物全部存活,且无创面感染情况发生,试验组术后创面干燥,2周结痂,3周脱痂并长出被毛;空白对照组术后1周创面表面局部有渗出,其余部位干燥,2周结痂,4周脱痂并长出被毛。创面愈合时间试验组为(20. 83±0. 75) d,空白对照组为(27. 33±0. 82) d。2周和3周时两组创面愈合率具有显著性差异。试验组术后3周皮肤各层结构清晰,烫伤面基本愈合,4周时皮肤各层结构完整;空白对照组皮肤各层结构和附件的形成与试验组相比皆滞后6 d左右。术后1周、2周和3周两组创面炎性细胞浸润情况和羟脯氨酸含量具有显著性差异。结论脱细胞生物敷料能够有效促进烫伤创面愈合,可缩短治疗周期。     

贵州草海保护区黑水鸡繁殖生态学观察

黑水鸡(Gallinula chloropus)是草海湿地的优势种和指示物种,对其开展繁殖生态学观察有利于对该物种进行科学管理和保护。2015年5-9月,在贵州草海保护区开展了黑水鸡繁殖生态学的研究。结果发现:黑水鸡的繁殖季为5-8月,喜好筑巢于靠近水边的水葱(Scirpus validus)群落中(97.6%),少数巢位于菰(Zizania latifolia)群落中(2.4%)。巢的外径为22.22±3.41 cm、内径13.42±2.22 cm、巢深5.22±1.32 cm、巢高13.90±2.81 cm。巢址特征为:巢上遮蔽度36.25%±35.94%、巢侧遮蔽度28.45%±28.27%、优势植物高度1.07±0.36 m、距离水面水平距离11.02±14.43 cm。黑水鸡的卵长径为42.34±0.13 mm(35.10~49.90,n=220),短径为30.11±0.09 mm(27.56~39.72,n=220),卵重为20.01±0.17 g(15.59~24.37,n=170),窝卵数为5.4±0.3枚(1~11,n=41)。黑水鸡受到的主要威胁为农民捡拾鸟卵,保护区应当重点加强这方面的管理。     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

An Index mechanism for multi-scale view in spatial databases

There are numerous geometric objects stored in the spatial databases. An importance function in a spatial database is that users can browse the geometric objects as a map efficiently. Thus the spatial database should display the geometric objects users concern about swiftly onto the display window. This process includes two operations:retrieve data from database and then draw them onto screen. Accordingly, to improve the efficiency, we should try to reduce time of both retrieving object and displaying them. The former can be achieved with the aid of spatial index such as R-tree, the latter require to simplify the objects. Simplification means that objects are shown with sufficient but not with unnecessary detail which depend on the scale of browse. So the major problem is how to retrieve data at different detail level efficiently. This paper introduces the implementation of a multi-scale index in the spatial database SISP (Spatial Information Shared Platform) which is generalized from R-tree. The difference between the generalization and the R-tree lies on two facets: One is that every node and geometric object in the generalization is assigned with a importance value which denote the importance of them, and every vertex in the objects are assigned with a importance value,too. The importance value can be use to decide which data should be retrieve from disk in a query. The other difference is that geometric objects in the generalization are divided into one or more sub-blocks, and vertexes are total ordered by their importance value. With the help of the generalized R-tree, one can easily retrieve data at different detail levels.Some experiments are performed on real-life data to evaluate the performance of solutions that separately use normal spatial index and multi-scale spatial index. The results show that the solution using multi-scale index in SISP is satisfying.     

A computer generator for randomly layered structures

AcomputergeneratorforrandomlylayeredstructuresYUJia shun1,2,HEZhen hua2(1.TheInstituteofGeologicalandNuclearSciences,NewZealand;2.StateKeyLaboratoryofOilandGasReservoirGeologyandExploitation,ChengduUniversityofTechnology,China)Abstract:Analgorithmisintrod…     

海南岛地体及其毗邻陆缘晚中生代—新生代古地磁研究和构造演化

本文叙述了对海南岛及其毗邻大陆边缘白垩纪到第四纪地层岩石进行古地磁研究的全部工作过程。通过分析岩石中剩余磁矢量的磁偏角及磁倾角的变化,提出海南岛白垩纪以来经历的构造演化模式如下:早期伴随顺时针旋转而向南迁移,后期伴随逆时针转动并向北运移。联系该地区及邻区的地质、地球物理资料,对海南岛上述的构造地体运动提出以下认识:北部湾内早期有一拉张作用,主要是该作用使湾内地壳显著伸长减薄,形成北部湾盆地。从而导致了海南岛的早期构造运动,而海南岛后期的构造运动则主要是受南海海底扩张的影响。海南地体运动规律的阐明对于了解北部湾油气盆地的形成演化有重要的理论和实际意义。     

Exciton Seebeck in Molecular Systems

Various applications relevant to the exciton dynamics,such as the organic solar cell,the large-area organic light-emitting diodes and the thermoelectricity,are operating under temperature gradient.The potential abnormal behavior of the exicton dynamics driven by the temperature difference may affect the efficiency and performance of the corresponding devices.In the above situations,the exciton dynamics under temperature difference is mixed with     

Achieving Unusual States of Matter Under High Pressure

The elongation method,originally proposed by Imamura was further developed for many years in our group.As a method towards O(N)with high efficiency and high accuracy for any dimensional systems.This treatment designed for one-dimensional(ID)polymers is now available for three-dimensional(3D)systems,but geometry optimization is now possible only for 1D-systems.As an approach toward post-Hartree-Fock,it was also extended to     

《Chinese Science Bulletin》SUBJECT INDEX TO VOLUME 59(2014)

正~~     

An on-line scaling method for improving scalability of a database cluster

The explosive growth of the Internet and database applications has driven database to be more scalable and available, and able to support on-line scaling without interrupting service. To support more client's queries without downtime and degrading the response time, more nodes have to be scaled up while the database is running. This paper presents the overview of scalable and available database that satisfies the above characteristics. And we propose a novel on-line scaling method. Our method improves the existing on-line scaling method for fast response time and higher throughputs. Our proposed method reduces unnecessary network use, i.e. , we decrease the number of data copy by reusing the backup data. Also, our on-line scaling operation can be processed parallel by selecting adequate nodes as new node. Our performance study shows that our method results in significant reduction in data copy time.     

An improved R-tree based on childnode''s probability

R-Tree is a good structure for spatial searching. But in this indexing structure,either the sequence of nodes in the same level or sequence of traveling these nodes when queries are made is random. Since the possibility that the object appears in different MBR which have the same parents node is different, if we make the subnode who has the most possibility be traveled first, the time cost will be decreased in most of the cases. In some case, the possibility of a point belong to a rectangle will shows direct proportion with the size of the rectangle. But this conclusion is based on an assumption that the objects are symmetrically distributing in the area and this assumption is not always coming into existence. Now we found a more direct parameter to scale the possibility and made a little change on the structure of R-tree, to increase the possibility of founding the satisfying answer in the front sub trees. We names this structure probability based arranged R-tree (PBAR-tree).     

Integrating GIS Web services based on mediating architecture

The geographic information service is enabled by the advancements in general Web service technology and the focused efforts of the OGC in defining XML-based Web GIS service. Based on these models, this paper addresses the issue of services chaining,the process of combining or pipelining results from several interoperable GIS Web Services to create a customized solution. This paper presents a mediated chaining architecture in which a specific service takes responsibility for performing the process that describes a service chain. We designed the Spatial Information Process Language (SIPL) for dynamic modeling and describing the service chain, also a prototype of the Spatial Information Process Execution Engine (SIPEE) is implemented for executing processes written in SIPL. Discussion of measures to improve the functionality and performance of such system will be included.