圆电流和亥姆霍兹线圈磁场的研究

根据毕奥-萨伐尔定律,导出了圆电流磁场分布的级数解表达式.应用磁场叠加原理,得到亥姆霍兹线圈的磁场分布的普遍表达式.由此讨论了亥姆霍兹线圈之间近轴和轴线上磁场的分布情况.并给出亥姆霍兹线圈产生均匀磁场区的条件.     

广义亥姆霍兹线圈中轴线上磁场的计算与分析

从毕奥—萨伐尔定律出发,结合亥姆霍兹线圈装置,首先研究了正三角形的广义亥姆霍兹线圈在其中轴线上的磁场分布情况。然后利用Mathematicas数值模拟了共轴正三角形线圈中心轴线上的磁场强度,得出了满足磁场均匀性的条件。     

霍尔效应法测量亥姆霍兹线圈空间磁场均匀区

分析了亥姆霍兹线圈空间磁场的分布，采用霍尔效应法探测亥姆霍兹线圈空间磁场，得到空间磁场均匀区的大小、形状及范围．     

亥姆霍兹线圈磁场的理论计算与实验讨论

首先,基于毕奥-萨尔定律分析了单个载流圆线圈在空间的磁场分布,得到了空间任意一点磁感应强度的积分表达式,并通过相应的计算得到了磁感应强度沿轴向和径向分量的解析结果;其次,将单个载流圆线圈在空间的磁场分布推广到亥姆霍兹线圈,获得了亥姆霍兹线圈在空间任一点磁感应强度的解析表达式,并利用Mathematica形象描绘了其磁感线分布;再次,通过数值计算分析了亥姆霍兹线圈的均匀磁场区;最后,结合"电磁感应法测量亥姆霍兹线圈磁场"实验作了相应的分析与讨论.     

基于磁纳米温度测量交变磁场激励系统设计

磁纳米温度测量方法有望解决肿瘤热疗中无法实现实时准确的温度测量问题.针对磁纳米温度测量方法在实际应用过程中存在的交变磁场均匀性低、信噪比低、负载阻抗较大的问题展开分析.首先通过分析交变磁场激励系统信号链,提出采用亥姆霍兹线圈作为交变磁场发生装置并从理论分析、模拟仿真和实际测量等层面分析并验证其磁场均匀性;其次针对信噪比低的问题提出采用九阶椭圆无源滤波器,分别通过理论分析、数字模拟仿真和实际测量等方面验证信噪比达到100 d B;最后依据阻抗匹配理论,提出利用串联谐振电路解决负载阻抗较大的问题,通过实际测量发现激励磁场强度达到20 Gs;同时为了解决交变磁场激励系统稳定性问题,提出采用串联大功率电阻的方式实时监测激励电流以保证激励磁场的稳定性.     

亥姆霍兹线圈磁场均匀性的研究

亥姆霍兹线圈轴线上中心点附近磁场的均匀性是很好的,本文通过理论计算和实验测定得知,亥姆霍兹线圈中心点附近轴线以外的磁场也是相当均匀的。     

亥姆霍兹线圈磁场均匀性的研究

为了探究亥姆霍兹线圈空间磁场均匀区域的大小、形状及范围,利用FD-HM-I型亥姆霍兹磁场测定仪及其所配备的高灵敏度毫特斯拉计传感器探头,探测了亥姆霍兹线圈轴截面上有限元磁场的大小,以两线圈中心连线的中点为坐标原点,建立坐标系,根据线圈的对称性,得到了亥姆霍兹线圈空间磁场均匀区域的大小、形状及范围.由于毫特斯拉计传感器探头的体积小、分辨率高,因此,该传感器适用于物理实验中弱磁场的测量,用它探测磁场准确度较高,误差较小。     

垂直三分量磁场发生器

用三组相同的亥姆霍兹线圈按照设计的构造图,做出三个垂直方向上磁场强度已知的三分量磁场发生器。通入线圈的电流是采用精度较高的可变恒流源,以减少温度等外界因素引起的误差。把恒流源接入三组线圈中,通过调节恒流源中的电阻,改变恒流源产生的电流的大小,从而控制了产生的三分量磁场的强度。     

平行共轴三线圈磁场均匀性分析

对平行共轴三个圆形线圈形成的匀强磁场进行了研究，通过数值计算，分析了平行共轴三线圈磁场的均匀性，计算结果表明，平行共轴三线圈系统的磁场强度、磁场均匀性及分布范围明显优于亥姆霍兹线圈，这为在小范围内形成匀强磁场提供了一个简单易行的方法。     

实验室中用多线圈获得匀强磁场设计的思考

在物理实验中,研究匀强磁场有重要作用。通过研究与比较单线圈、亥姆霍兹线圈、三线圈的磁场,得出三线圈的磁场在均匀性和强度上均超过了单线圈和亥姆霍兹线圈。     

基于MATLAB的亥姆霍兹线圈轴线磁场均匀分布的动态仿真

MATLAB软件为复杂、抽象物理现象的动态仿真提供了简单、高效的编码环境.文章在分析亥姆霍兹线圈轴线磁场分布现象的数学模型基础上,提出了一种运用MATLAB软件对亥姆霍兹线圈轴线磁场均匀分布进行验证及仿真的方法.该方法能够简便、直观地展现亥姆霍兹线圈轴线磁场均匀分布的这一物理现象.     

Effect of local hyperthermia induced by nanometer magnetic fluid on the rabbit VX2 liver tumor model

Hyperthermia induced by magnetic nanoparticles is a recent therapeutic approach for local targeting of hyperthermia and thermoablation and is a promising treatment of malignant tumors.The purpose of this study is to evaluate the potential and therapeutic effect of magnetic fluid hyperthermia on the rabbit VX2 liver tumor model.Rabbits bearing liver tumors 14 days after tumor implantation were randomly divided into five groups of 10 cases each,including three control groups and two hyperthermia groups.Hyperthermia was carried out immediately after a single intratumoral injection of uncoated water-based Fe3O4 magnetic fluid under an alternating magnetic field only once as one hyperthermia group and repeated hyperthermia after 5 days as the other treated group.The distribution of magnetic fluid was evaluated by CT scanning.All animals were sacrificed 4 weeks after tumor implantation.The therapeutic effect was determined by tumor size and macroscopic and pathological examination of the liver tumor.The local higher density imaging of intratumoral magnetic fluid deposits compared to the surrounding tissue was clearly observed by CT scanning.Twenty-eight days after tumor implantation,the tumor maximal diameter and tumor volume of two hyperthermia were both significantly less than those of control groups (P＜0.05).Tumor volume inhibition by single or repeated hyperthermia compared to the three control groups was 71.93-79.91% and 92.34-94.46% (P＜0.05),respectively.Under a microscope,coagulation necrosis was observed in the heated area,which had a clear boundary line with the surrounding tissue.The intratumoral distribution of magnetic nanoparticles,especially in the area of necrosis,appeared much more homogenous than in the untreated ones.This study demonstrates that hyperthermia induced by direct intratumoral injection of magnetic fluid can be used safely,and a well-homogenized distribution of high intratumoral temperature without heating adjacent to normal tissue can be achieved.     

Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia

In the process of ferromagnetic thermoseeds mediated magnetic induction hyperthermia, the tempera- ture distribution in the tumor region is a key factor to determine the therapy effect. During the preoperative treatment planning, discrepancies of the treatment parameters may lead to the temperature distribution uncertainty within the target area. Inaccurate prediction of temperature distribution may induce the treatment failure; therefore, it would be significant to investigate the uncertainty of tissue temperature prediction caused by the disturbance of calculation parameters. In this paper, 3D temperature field and necrosis zone of tissues in ferromagnetic thermoseeds hyperthermia are simulated by the finite volume algorithm, and effects of parameter uncertainties on the temperature distribution are revealed. Results show that selecting appropriate magnetic field parameters for treatment is a priority to guarantee therapeutic effect. Thermoseed properties and blood perfusion rate are the obvious disturbing terms for temperature distribution, while the metabolic heat of bio-tissues can often be ignored within limits. Our investigation is of importance for guiding reasonable and optimal preoperative treatment planning.     

均匀磁场激励磁感应成像滤波反投影算法

通过亥姆霍兹线圈在中心区域建立正弦均匀的激励磁场,磁场方向近似直线,有助于简化逆问题的复杂度.建立了8通道磁感应测量系统仿真模型,采用滤波反投影算法重构出电导率分布.在滤波反投影算法中,首先用线性插值补充检测数据,然后用Hamming滤波器对数据进行滤波,同时加入窗口滤波器减少了涡流磁场发散对周围线圈的影响.加入不同噪声比的噪声干扰,测试了算法对噪声的抑制能力,实验结果表明该模型下运用反投影滤波算法可以重构出电导率的分布.