科技创业孵化载体专业化发展问题与对策研究

进入新发展阶段后,科技创新创业活动对孵化服务提出了更高的要求,科技创业载体需要加快提升专业化、精准化服务能力.文章基于2016-2019年全国科技创业孵化载体发展数据,全面分析专业化科技创业孵化载体建设发展现状,剖析了科技创业孵化载体在专业化建设方面存在的方向不清、动力不足、能力不够、模式不明、机制不畅等问题,从建立评价指标体系、明确建设主体、提升服务能力、加强资源开放和政策供给等方面提出对策建议.     

腹外侧视前区微量注射组胺对大鼠睡眠-觉醒周期的影响

目的 研究组胺作用于腹外侧视前区对大鼠睡眠-觉醒周期的影响。方法 通过脑立体定位、腹外侧视前区微量注射组胺,脑电图仪记录及分析睡眠、觉醒时相。结果 微量注射50μmol/L组胺无明显影响,而100μmol/L组胺显著减少大鼠睡眠,增加觉醒。结论 组胺在腹外侧视前区对大鼠睡眠-觉醒周期发挥重要的调节作用,具有明显的促觉醒作用。     

Spatial dependence model with feature difference

This paper presents a new spatial dependence model with an adjustment of feature difference. The model accounts for the spatial autocorrelation in both the outcome variables and residuals. The feature difference adjustment in the model helps to emphasize feature changes across neighboring units, while suppressing unobserved covariates that are present in the same neighborhood. The prediction at a given unit incorporates components that depend on the differences between the values of its main features and those of its neighboring units. In contrast to conventional spatial regression models, our model does not require a comprehensive list of global covariates necessary to estimate the outcome variable at the unit, as common macro-level covariates are differenced away in the regression analysis. Using the real estate market data in Hong Kong, we applied Gibbs sampling to determine the posterior distribution of each model parameter. The result of our empirical analysis confirms that the adjustment of feature difference with an inclusion of the spatial error autocorrelation produces better out-of-sample prediction performance than other conventional spatial dependence models. In addition, our empirical analysis can identify components with more significant contributions.     

Theoretical and experimental design of Pt-Co(OH)_2 electrocatalyst for efficient HER performance in alkaline solution

Design efficient electrocatalysts become significant for the hydrogen evolution reaction (HER) in alkaline solution.Here,the HER performance on Pt-Co(OH)2 has been investigated by using DFT calculations.Compared with pure Pt,the Pt-Co(OH)2 shows excellent hydrogen binding energy (-0.29 eV) and hydrogen adsorption free energy (0.02 eV).More strikingly,the water dissociation process on Pt-Co(OH)2 is an exothermic reaction while that of Pt is an endothermic reaction,demonstrating that the Pt-Co(OH)_2 is an excellent catalyst for HER in alkaline medium.Then the two-step electrodepositions was used to fabricate Pt-Co(OH)2 on the carbon paper (CP).The Pt-Co(OH)_2/CP shows the lowest overpotential of only 37.6 mV at a current density of 10 mA cm~(-2) in 0.1M KOH,the smallest Tafel slope of58 mV dec~(-1) and the good stability for 20000s without obvious degradation.     

Processing and characterization of the microstructure and mechanical properties of Al6061–TiB2 composite

In the present research, aluminum metal matrix composites were processed by the stir casting technique. The effects of TiB2 rein-forcement particles, severe plastic deformation through accumulative roll bonding (ARB), and aging treatment on the microstructural charac-teristics and mechanical properties were also evaluated. Uniaxial tensile tests and microhardness measurements were conducted, and the micro-structural characteristics were investigated. Notably, the important problems associated with cast samples, including nonuniformity of the rein-forcement particles and high porosity content, were solved through the ARB process. At the initial stage, particle-free zones, as well as particle clusters, were observed on the microstructure of the composite. However, after the ARB process, fracturing phenomena occurred in brittle ceramic particles, followed by breaking down of the fragments into fine particles as the number of rolling cycles increased. Subsequently, com-posites with a uniform distribution of particles were produced. Moreover, the tensile strength and microhardness of the ARB-processed com-posites increased with the increase in the reinforcement mass fraction. However, their ductility exhibited a different trend. With post-deforma-tion aging treatment (T6), the mechanical properties of composites were improved because of the formation of fine Mg2Si precipitates.     

继续教育质量保障体系建设的研究与实践

教学质量是教育的核心问题。继续教育的质量保障体系建设,既是继续教育服务学生、服务社会经济发展的必然需求,也是普通高校继续教育发展的自身保障。本文紧扣继续教育质量保障体系建设的工作实践,围绕继续教育现状分析、质量保障体系内涵认知、质量保障体系创建举措与特色等方面进行知行合一的研究论述。     

典则分析研究柴胡达原饮不同煎煮方式对化学成分溶出的影响

研究柴胡达原饮多种分煎、合煎方式对柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、厚朴酚5种成分溶出的影响.将柴胡达原饮方中10味中药材,按照君臣佐使分为4组:A(黄芩、柴胡),B(枳壳、桔梗、厚朴、草果、青皮、槟榔),C(荷叶),D(炙甘草).按照排列组合排成15种组合方式.采用UFLC检测提取液中柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、厚朴酚的含量.运用SAS 9.1对数据进行相关分析和综合评判.结果发现:5种成分均能达到基线分离,各成分均有较宽的线性范围和良好的线性关系;枳壳在合煎、分煎中受到的影响与青皮、厚朴是不同的;较佳组合为ACD+B,柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、厚朴酚的含量分别为1.3130、0.6370、1.9420、0.8786、0.6110 mg/mL.ACD+B方式分煎,5种成分的溶出最大;相关分析能较好地揭示各组分的相互关系.     

大思政教育背景下软件工程课程思政教学改革探索与实践

为更好地将专业教育与思政教育有机融合,充分发挥专业课程的育人功能,各学校积极开展课程思政教学改革试点工作,逐步形成"大思政"教育体系。以专业主干课程软件工程为例,在分析教学内容和目标基础上,从科学素养培养、创新意识强化、生活处事哲理灌输等方面阐述了该课程开展课程思政的着眼点,并分别从教学内容设计、教学方法改革和教学评价改进等方面详细分享了开展课程思政的经验和做法。实践表明,上述措施切实加强了学生科学素养、法治素养、民族自信和创新意识的培养,达到了课程思政教育的目的,取得了较为满意的效果。