TV-SHG对子宫内膜疾病的诊断价值

目的探讨高频阴道彩超下宫腔声学造影(TV-SHG)对子宫内膜疾病的诊断价值.方法本研究通过经宫腔声学造影的方法,对150例患者阴道彩超声检查(TVS),并将宫腔声学造影前后超声表现与病理结果比较.结果TVS的敏感性为85.5%,特异性为76.9%,总符合率84.0%;TV-SHG的敏感性为96.8%,特异性为84.6%,总符合率94.7%;TV-SHG与病理诊断的符合率、敏感性、特异性明显高于TVS,二者相比有显著性差异(P<0.05).结论SHG较TVS能够迅速准确地诊断子宫内膜疾病,为临床提供可靠的诊断依据.     

窄带成像内镜在慢性胃炎平坦型病变中临床诊断价值

目的探讨窄带成像内镜在慢性胃炎平坦型病变中的诊断价值.方法选取100例门诊患者,在常规内镜下发现慢性胃炎平坦型病变再转化为窄带成像模式进行观察,在选取部位进行病理活检,以病理诊断为"金标准"进行诊断、比较.结果普通白光内镜下总病理符合率为71.3%,窄带成像内镜下总病理符合率为91.6%,两种情况下总病理符合率具有统计学意义(P<0.05),尤其在诊断炎症伴肠上皮化生、炎症伴上皮内瘤变、早期胃癌时,窄带成像内镜明显优于普通白光内镜.结论窄带成像内镜在慢性胃炎平坦型病变中的诊断率好于普通白光内镜,尤其对早期胃癌、上皮内瘤变等病变有更好的诊断价值.     

Do prostaglandins mediate the somatostatin preventive effect on gastric lesion?

Summary The inhibition of endogenous prostaglandin synthesis by indomethacin treatment blocks the somatostatin preventive effect on the gastric lesions induced in a stress model and has no preventive effect on an intragastric distension model.     

糖尿病下肢血管病变患者血脂、纤维蛋白原水平变化的研究

目的：探讨2型糖尿病合并下肢血管病变患者血脂、纤维蛋白原水平变化及其意义。方法：对55例2型糖尿病患者行双下肢动脉超声检测，根据有无下肢血管病变分为糖尿病合并下肢血管病变组（实验组）23例和无下肢血管病变组（对照组）22例，并作血糖、血脂和纤维蛋白原等含量测定。结果：两组总腮固醇、甘油三脂、高密度脂蛋白等均无统计学差异，糖尿病下肢血管病变组较无血管病变组低密度脂蛋白、纤维蛋门原明显增高（P〈0．05）。结论：糖尿病合并下肢血管病变患者存在血脂、血凝功能异常，低密度脂蛋白和纤维蛋白原的异常增加是糖尿病下肢血管并发症的重要原因。     

Isolation and characterization of rice lesion mimic mutants from a T-DNA tagged population

A rice ( Oryza sativa L. ssp. japonica cv. Nipponbare) T-DNA tagged population consisting of about 7000 individual lines was generated and screened for rice lesion mimic mutants in the T1 generation. Ten lines were found to develop spontaneous lesions in the absence of pathogen infection and displayed distinct lesion phenotypes. These mutants were tentatively designated as lm1 -lm10 (for lesion mimic), respectively. Lesion formation of lm mutants was developmentally regulated, and all the mutants showed stunted growth and reduced fertility. Genetic analysis demonstrated that all the mutations were recessive, and five partially fertile mutants (lm4-lm8) were derived from different loci. Mimic lesions occurring on the leaves of lm mutants resulted from cell death as revealed by trypan blue staining. Six of them ( lm3 -lm8 ) exhibited enhanced resistance to five bacterial blight isolates, indicating their wide-spectrum resistance to this pathogen. These results imply that some lesion mimic mutations of rice might be involved in disease resistance signaling pathways,and that isolation of these mutated genes may be useful for elucidating molecular mechanisms of plant disease resistance. Among the mutants, only one mutant, lm6, was preliminarily shown to cosegregate with the inserted T-DNA in its T1 generation, making it feasible to isolate the gene responsible for the phenotype of this mutant.     

眼镜蛇毒神经生长因子对成年猫坐骨神经损伤治疗效果的实验室观察

目的 :探讨从眼镜蛇毒分离纯化出的神经生长因子(nervegrowthfactor,NGF)对成年猫坐骨经损伤后的影响。方法 :本实验制成成年猫坐骨神经损伤模型 ,损伤局部注射蛇毒NGF(2μg/kg/d) ,分别治疗10d和30d ,并与对照组(损伤坐骨神经 ,不给药物)比较。结果 :眼镜蛇毒NGF在神经损伤早期应用能减轻神经纤维发生的溃变 ,促进神经纤维再生。结论 :损伤局部长时间注射NGF会导致神经纤维增生过度 ,丧失传导功能     

神经导航系统在颅内病变显微手术中的应用

应用神经导航系统进行颅内病变显微手术50例.本组颅内病变及其周围解剖结构定位准确,平均注册误差 2.4±0.4 mm.术后近期复查颅脑MR证实肿瘤全切率92%,手术并发症10%,手术时间和住院日较常规开颅手术缩短.结果表明:1)神经导航系统术前计划定位精确;2)实时导航下颅内病变显微手术,有助于达到微侵袭效果和提高肿瘤全切除率.     

腹腔内巨大囊性占位性病变的CT诊断困境探讨

目的分析腹腔内巨大囊性占位性病变的CT表现,并重点探讨其在CT诊断方面的价值.病灶体积较大失去了原病灶的典型影像表现容易导致判断失误和误诊.方法搜集经手术病理证实的巨大囊性占位性病变共14例,其中腹腔内囊腺瘤8例,其中1例为超级巨大型;囊腺癌2例;子宫内膜异位囊肿2例;肠系膜囊肿2例.所有病例都经过平扫,部分经过平扫加增强扫描或三维重建.结果:14例病人都诊断为囊腺瘤,腹腔内囊腺瘤的正确诊断例数为8例,其中4例未做增强扫描,诊断困难,有2例误诊.结论:腹腔内巨大囊性占位性病变具有相似的CT特征,在病灶体积较大的情况下病灶失去了部分典型影像表现,从而对疾病的正确诊断带来一定的困难,尤其在定位定性诊断上经验不足,认识这些困难有助于掌握巨大囊性占位性病变在疾病发展中的一般规律.