轧制道次间插入冷却对特厚钢板组织与性能的影响

使用实验轧机旁冷却装置配合轧机进行轧制实验，研究轧制道次间不同冷却工艺对特厚钢板组织和性能的影响规律.研究结果表明:采用道次间冷却工艺可以在全厚度方向获得组织细化及强韧性提高效果，采用强冷道次间冷却实验钢1/4处晶粒尺寸可细化至10μm，强度为376MPa，-40℃冲击功为169J;心部晶粒尺寸可细化至15μm，强度为360MPa，-40℃冲击功为123J.本工艺可形成470μm厚表层细晶层，晶粒尺寸可细化至5μm;粗轧道次间插入冷却工艺轧制钢板强度和冲击韧性优于中间坯冷却工艺;随冷却强度增加，钢板内部组织明显细化且强度大幅提高.     

带有临界增长的Kirchhoff方程极小能量变号解的存在性

为了深入研究Kirchhoff方程的性质,讨论了带有Hartree项和临界增长非线性项的Kirchhoff方程极小能量变号解的存在性。利用能量泛函在变号Nehari流形上的下确界C_λ收敛于0,得到空间E紧嵌入L~6(R~3)这一技术性结果。结果表明,利用限制变分方法和定量形变引理获得极小化序列对应的极小值点是该问题的非平凡解。研究方法在理论证明方面得到了良好的结果,对研究其他Kirchhoff方程解的存在性有一定的指导意义。     

交变磁场对磁性磨粒的作用分析

对处于交变磁场作用下的磁性磨料颗粒的受力和运动规律进行了分析和描述，为交变磁场作用下的磁粒研磨光整加工技术提供了新的思路和工艺选择。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

基于系统动力学理论建模的教育投资、经济增长和就业问题的研究

运用系统动力学的理论、方法构建模型,对教育投资、经济增长与就业问题进行了模拟,提出应加大教育投资力度,提高国民教育水平,将巨大的人口压力转化为巨大的人力资本优势,同时也必须兼顾由于人口总量以及其他因素导致的巨大的就业压力问题,在教育投资与固定投资之间保持合理的比例关系,以促进经济的持续、适度发展,为政府决策提供参考和依据。     

花岗岩磨削磨粒破碎性能研究

花岗岩是一种含硅酸量较多的酸性深层岩。目前国内的石材加工由于磨削工艺不尽合理,磨削质量不符要求,因而需依靠进口磨具。本实验通过不同磨料对不同花岗岩进行单颗粒磨削,探索其规律,为合理选择和使用磨具提供理论依据。     

“926”植物生长调节剂的药效作用及机理研究

试验表明，“９２６”植物生长调节剂对植物种子活力、根系活力、植物生长发育具有明显的促进作用。用“９２６”浸稻种和玉米种，可提高发芽势、发芽率，增加次生根数和次生根长。苗期施药，同样可促进幼苗生长发育、促进根系发育、增加分蘖、分枝，提高成穗率。其它生育期施药，可分别提高成稳率、穗粒数、粒重，显著提高作物产量。     

上皮生长因子预防心脏术后心包粘连的实验及临床研究

目的探讨上皮生长因子(EGF)对心脏术后心包粘连的预防作用.方法术中对犬心包内喷洒上皮生长因子3个月后,观察心包粘连情况;选先天性心脏病、房缺及室缺病人40例,术中心包内喷洒上皮生长因子,术后6个月、12个月经CT检查,判定心包粘连、增厚结果.结果在动物实验和临床研究中,实验组粘连程度显著低于对照组(P<0.01).结论 EGF心包内应用有明显预防心脏术后心包粘连的作用.     

Microstructure transition of Al-Cu eutectic alloy during containerless rapid solidification

Droplets of Al-32.7%Cu eutectic alloy were rapidly solidified during containerless processing in a 3 m drop tube. The microstructural evolution of Al-Cu eutectic alloy depends strongly on droplet size. The eutectic growth morphology changes from regular lamellar eutectic to a kind of anomalous eutectic with the decrease in droplet size. This microstructural transition was analyzed within the current theories of eutectic growth. The results indicate that there exists a critical velocity for eutectic growth beyond which anomalous eutectic appears. The coupled zone of the Al-Cu eutectic alloy system has been calculated on the basis of the Trivedi-Magnin-Kurz(TMK) eutectic growth and the Lipton-Kurz-Trivedi(LKT)/Boettinger-Coriell-Trivedi(BCT) dendrite growth models, which provides a further interpretation for the morphological transition.