| 上皮生长因子预防心脏术后心包粘连的实验及临床研究 |
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| 引用本文： | 张世群,汪建中,邹本峰,李海滨,张波,李强.上皮生长因子预防心脏术后心包粘连的实验及临床研究[J].北华大学学报(自然科学版),2002,3(2):133-134,151. |
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| 作者姓名： | 张世群 汪建中 邹本峰 李海滨 张波 李强 |
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| 作者单位： | 北华大学医学院附属医院,吉林,吉林,132011 |
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| 摘 要： | 目的探讨上皮生长因子(EGF)对心脏术后心包粘连的预防作用.方法术中对犬心包内喷洒上皮生长因子3个月后,观察心包粘连情况;选先天性心脏病、房缺及室缺病人40例,术中心包内喷洒上皮生长因子,术后6个月、12个月经CT检查,判定心包粘连、增厚结果.结果在动物实验和临床研究中,实验组粘连程度显著低于对照组(P<0.01).结论 EGF心包内应用有明显预防心脏术后心包粘连的作用.
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| 关 键 词： | 上皮生长因子 心包粘连 预防 心脏术后 |
| 文章编号： | 1009-4822(2002)02-0133-02 |
The Experiment and Clinical Research on the Epithelial Growth Factor for Prevention of Pericardial Adhesion after Cardiac Operation |
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| Zhang Shiqun,Wang Jianzhong,Zou Benfeng,Li Haibin,Zhang Bo,Li Qiang.The Experiment and Clinical Research on the Epithelial Growth Factor for Prevention of Pericardial Adhesion after Cardiac Operation[J].Journal of Beihua University(Natural Science),2002,3(2):133-134,151. |
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| Authors: | Zhang Shiqun Wang Jianzhong Zou Benfeng Li Haibin Zhang Bo Li Qiang |
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| Abstract: | Objective To explore the prevention effect of epithelial growth factor on pericadial adhesion after cardiac operation.Methods After 3 months by sprinkling EGF in dog pericardium were observed and selection of 40 patients with congenital heart disease, septal defect were judged the result of pericardial adhesion by CT after cardiac surgery 6 months and 12 months.Results The degree of pericardial adhesion of experimental group is lower than that of control group significantly (P<0.01).Conclusion Sprinkling EGF in pericardium can prevent from pericardial adhesion following cardiac surgery. |
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| Keywords: | Epithelial growth factor Pericardial adhesion Prevention Following cardiac surgery |
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