络合物稳定常数的微机数据处理

探讨pH法测定铜-磺基水杨酸累积稳定常数的微机数据处理。根据Bjerrum“生成的数”概念,推导出计算公式,用BASIC语言编写,在APPLEⅡ机上分钟内就能完成,此法也适用于弱酸或弱硷离解平衡常数和弱酸弱硷与各金属离子生成络合物累积稳定常数的测定。     

The preparation and application of microbubble contrast agent combining ultrasound imaging and magnetic resonance imaging

Encapsulated gas microbubbles are well known as ultrasound contrast agents （UCAs） for medical ultrasound （US） imaging. With the development of shell materials and preparation technologies, the application of microbubbles has been enormously popular in molecular imaging, drug delivery and targeted therapy, etc. The objective of this study is to develop Fe3O4 nanoparticle-inclusion microbubble construct. The in vitro US imaging experiment indicates that the Fe3O4 nanoparticle-inclusion microbubbles have higher US enhancement than those without Fe3O4 nanoparticle-inclusion. According to the microbubble dynamic theory, the acoustic scattering properties can be quantified by scattering cross-section of the shell. The scattering study on Fe3O4 nanoparticle-inclusion microbubbles of different concentration shows that within a certain range of concentration, the scattering cross-section of microbubble increases with the addition of Fe3O4 nanoparticles. When exceeding the concentration range, the ultrasonic characteristic of microbubbles is damped. On the other hand, since Fe3O4 nanoparticles can also serve as the Magnetic Resonance Imaging （MRI） contrast agent, they can be potentially used as contrast agents for the double-modality （MRI and US） clinical studies. However, it is important to control the concentration of Fe3O4 nanoparticles in the shell in order to realize the combined functions of US and MRI.     

The altitude effect of δ 18O in precipitation and river water in the Southern Himalayas

The lapse rate of water isotopes is used in the study of the hydrologic cycle as well as in the estimation of uplift of the Tibetan Plateau.The greater elevation contrast in the Southern Himalayas allows for a detailed discussion about this lapse rate.We analyze variations of 18δO in precipitation and river water between 1320 m and 6700 m elevations in the Southern Himalayas,and calculate the specific lapse rate of water 18δO.The results show that the multi-year average lapse rate in precipitation over this region is 0.15‰/100 m.The one-year average lapse rate is 0.17‰/100 m from three sites along the Southern Himalayas.The two results agree,but are much lower than the global average of 0.28‰/100 m.This work also shows that there is a difference in precipitation 18δO lapse rate between the monsoon and non-monsoon seasons.The calculated precipitation lapse rate is much lower than that in surface water.     

新型HLA-A2限制的B, C型HBV特异性CTL表位的筛选及鉴定

乙型肝炎病毒(HBV)特异性CD8+ T细胞(CTL)介导的细胞免疫应答在控制HBV感染和病毒清除中至关重要, 已鉴定的T细胞表位绝大多数都来自A, D基因型的乙肝病毒, 而在我国流行的B, C型病毒表位研究较少. 本研究合成重叠九肽肽库, 通过细胞结合试验和体外重折叠实验系统筛选和鉴定B型和C型HBV核心蛋白表位, 发现一个在60位氨基酸由L变异成V(L60V)而产生的新表位HBcAg60-68. 表位肽能在HLA-A2/K^b转基因小鼠体内激发特异性CTL细胞免疫反应. 检测HLA-A2阳性乙肝患者表位特异性CTL证明该九肽序列为体内自然加工的表位, 这为研究HBV感染中特异性CTL免疫应答提供新的依据.     

素理想是完全素的Γ-环( 英文 )

讨论两类Γ─环：素根等于幂零元集的Γ─环类；素理想是完全素的Γ─环类．给出了它们的性质．最后证明：若Γ─环M有强右单位，R是M的右算子环，则M是2－primal当且仅当是R是2－primal环．     

高精度千赫兹重复频率卫星激光测距系统及实测结果

千赫兹重复频率激光测距具有目标捕获快、回波数多、测距精度高、标准点数据密度高等优点, 已成为国际激光测距技术的发展趋势. 针对千赫兹激光测距系统, 中国科学院上海天文台采用皮秒脉宽千赫兹频率激光器和高精度事件计时器, 研制了纳秒级控制精度的事件模式距离门控及后向散射避免电路, 设计开发高实时性控制软件和数据预处理软件, 建立了高精度千赫兹重复频率卫星激光测距系统, 实现了从低轨到中高轨卫星千赫兹重复频率常规观测和低轨道卫星白天测距, 测距精度7~12 mm, 并在国际上首先实现了同步轨道卫星千赫兹重复频率激光测距. 与低重复频率激光测距相比, 激光测距有效回波数和标准点数据密度有数量级增加, 测距精度也有了一定的提高.