基于AHP的维修服务质量评价研究

分析了进行维修服务质量评价的重要性，建立了维修服务质量评价的层次结构，提出了分析模型和计算方法，并给出了一个具体实例，通过应用AHP方法，能优先考虑判断准则，由此得到维修服务质量的逆序排列，从而能评选出维修服务质量最优的维修商，该方法可减少人为因素的影响，增强决策的客观性和科学性。     

企业员工-管理者互动行为的定性模拟实现

采用定性模拟方法研究了企业员工一管理者互动行为．根据定性模拟和组织行为学相关理论，将管理者任职后与下属员工相处的过程视为相互影响的动态变化过程，建立了能够表达这种动态变化的定性状态变量和作用规则；采用C＋＋语言实现了定性模拟程序QSHR；通过一个例子的有效性验证说明所设计程序能够表达互动行为的定性模型，所得结论符合管理原则．通过一个对比不同状态下管理者和员工群体行为表现实际应用，论述了QSHR的应用方法和对管理实践的重要参考意义．     

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140?mm?Hg systolic blood pressure or ≥90?mm?Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3-GUCY1B3, NPR3-C5orf23, ADM, FURIN-FES, GOSR2, GNAS-EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function. We also observed associations with blood pressure in East Asian, South Asian and African ancestry individuals. Our findings provide new insights into the genetics and biology of blood pressure, and suggest potential novel therapeutic pathways for cardiovascular disease prevention.     

物资管理数据库逻辑设计的E-R模型

本文根据系统分析与设计的E-R方法的基本原理,结合物资管理数据库设计实践,讨论了E-R模型的建立和转换问题。     

报高率确定决策事例的检索、匹配与调整

分析报高率决策事件的特征，提出了报高率确定决策事例的层次结构表示方法，研究了事例的组织与管理模式；对报高率确定决策事例的相似性进行了研究，提出了用贴近度表示报高率确定决策事例的相似度，利用灰色系统的预测理论，提出了一种报高率确定决策事例的调整模型。     

多激励合同定价中最优风险分担率的研究

提出了多激励定价模型的最优解满足的条件,解释了最优解所包含经济含意,并通过定价实例说明了多激励定价模型的优越性.     

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland

The NOTCH4 gene was recently reported to be associated with schizophrenia based on TDT analysis of 80 British trios. The strongest evidence for association derived from two microsatellites. We genotyped both loci in a large sample of unrelated Scottish schizophrenics and controls, but failed to replicate the reported association, finding instead that each putative schizophrenia-associated allele had a somewhat lower frequency in schizophrenics than in controls.     

Nitrogen fixation. Endocrine disrupters and flavonoid signalling

Nitrogen fixation is a symbiotic process initiated by chemical signals from legumes that are recognized by soil bacteria. Here we show that some endocrine-disrupting chemicals (EDCs), so called because of their effect on hormone-signalling pathways in animal cells, also interfere with the symbiotic signalling that leads to nitrogen fixation. Our results raise the possibility that these phytochemically activated pathways may have features in common with hormonal signalling in vertebrates, thereby extending the biological and ecological impact of EDCs.