孕早期睡眠时长与午睡频次对妊娠糖尿病的影响

目的探讨孕早期睡眠时长和午睡频次对妊娠糖尿病(GDM)的影响。方法采用病例对照研究设计,选取2018年4月至2019年5月在安徽省妇幼保健院、吉安市妇幼保健院产检的孕妇作为研究对象。通过问卷调查收集研究对象的睡眠和午睡等信息,GDM的诊断来自孕中期常规口服葡萄糖耐量试验结果。结果共纳入500名研究对象,其中病例组196人,对照组304人。多元Logistic回归分析结果显示,与睡眠时长7～8.9 h/晚相比,睡眠7、9～9.9、≥10 h/晚的孕妇发生GDM的风险均显著上升;与午睡频次≤5 d/周相比,5 d/周的孕妇发生GDM的风险更高。相比孕早期午睡频率≤5 d/周的孕妇,孕早期睡眠时长不足(7 h/晚)对GDM的影响在午睡频率5 d/周的孕妇中更弱,交互作用具有统计学意义(P=0.002)。结论孕早期睡眠时长、午睡频次均与GDM发病相关,且二者在GDM的发生中存在交互作用。     

The coconut pathosystem: weed hosts of nymphs of the American palm Cixiid Haplaxius crudus (Hemiptera: Fulgoroidea)

Lethal yellowing (LY) of coconut palm (Cocos nucifera L., Arecaceae) is a disease of economic importance that is caused by the phytoplasma ‘Candidatus Phytoplasma palmae’ and is transmitted by the planthopper Haplaxius crudus (Van Duzee) (Hemiptera: Cixiidae). This study explores the weeds used by H. crudus nymphs and other Cixiidae in a coconut pathosystem in southern Mexico. Nymphs were collected directly from the root system of each weed by hand or with the help of a vacuum after carefully opening the culm. This study included 11 species of weeds: nine Poaceae [Brachiaria decumbens Stapf, B. humidicola (Rendle) Schweick, B. mutica (Forssk.) Stapf, Digitaria abyssinica (Hochst. Ex A. Rich.) Stapf, Eustachys petraea (Sw.) Desv., Leersia hexandra Sw., Panicum laxum Sw., P. maximum Jacq., Paspalum notatum Flüggé]; one Cyperaceae [Cyperus ligularis L.], and one Portulacaceae: [Portulaca pilosa L.]. Brachiaria mutica, E. petraea, B. humidicola, P. maximum were identified as the principal host species for H. crudus nymphs. Brachiaria decumbens, D. abyssinica, and C. ligularis are new host records for the nymphs of H. crudus. Additionally, it was found that H. crudus may coexist with its cogeners H. skarphion Kramer (Cixiidae) and H. caldwelli Kramer (Cixiidae), on B. mutica. On C. ligularis, H. crudus may coexist with Oecleus snowi Ball (Cixiidae) nymphs. These results suggest that in the coconut pathosystem there is a complex of multitrophic interactions that should be considered in integrated management of LY.     

复杂场景散射中心模型化与雷达成像应用

在复杂场景中, 目标与环境之间的耦合散射会造成雷达图像特征的干扰, 这一问题给雷达目标自动识别与跟踪技术带来了困难, 成为雷达、电磁领域持续关注的热点研究问题。目前, 使用传统的电磁数值计算方法对复杂场景散射问题进行仿真, 所需计算资源巨大, 耗时很长, 而且多限于针对单一类型复合目标, 难以满足实际工程应用需求。针对此问题，提出了复杂场景散射中心模型化的方法, 集成散射中心模型、物理光学法、积分方程法、四路径模型、射线追踪等方法为一体, 实现了复杂场景、群目标雷达成像快速仿真。本文给出了三种有代表性的复杂场景的逆合成孔径雷达成像仿真结果, 验证了本文方法的可行性及泛用性。     

Haversian bone-mimicking bioceramic scaffolds enhancing MSC-macrophage osteo-imunomodulation

The interaction between immune cells and bone forming cells plays a vital role in maintaining the homeostasis of the skeletal system, and is regulated by the three-dimensional structure of tissues. Whether the construction of biomaterials can activate or reproduce this spatial “cross-talk” between immune cells and bone forming cells in bone natural formation process is a prerequisite for successful fracture healing and bone regeneration. Herein, a bone marrow mesenchymal stem cells (MSCs)/macrophages-laden Haversian bone-mimicking bioceramic scaffold was successfully prepared through the biomimetic design of biomaterials and 3D printing technology. MSCs and macrophages were respectively distributed in the cancellous bone and Haversian canals of the scaffold to simulate the three-dimensional structure regulation of the cell spatial distribution and multiple intercellular interaction in natural bone tissue, and worked in concert to modulate the scaffold material-mediated osteo-immune microenvironment. The in vitro study revealed that the pro-inflammatory response of macrophages was more significantly inhibited when distributed with MSCs in the scaffolds at a cell ratio of 0.5:1 for co-culture, in comparison with multicellular culture at other ratios and unicellular culture. Meanwhile, MSCs exhibited the relatively high osteogenic potential, most likely via the activation of certain key signaling pathways mediated by macrophages-derived paracrine signaling mediators (OSM, BMP-2, and WNT10b). This work not only establishes a bionic platform for the regulation of multicellular osteo-immune response and regeneration but also offers a promising tissue-engineered biomimetic scaffold with improved immunomodulatory function for promoting bone tissue regeneration.     

双自由度磁悬浮式桥梁振动能量采集器数值仿真和优化

提出了一种能利用桥梁振动能量为传感器持续供电的双自由度磁悬浮振动能量采集器(TMEH),该系统的能量采集效率远高于传统单自由度磁悬浮振动能量采集器(SMEH).推导了TMEH系统的运动控制方程和机电耦合方程;建立了TMEH的多目标优化模型,提出了基于NSGA2算法的能量采集器参数优化设计方法;最后将TMEH和SMEH在简谐振动激励和桥梁随机振动激励作用下的响应特性和能量采集效率进行了对比.研究结果表明:1)通过NSGA2算法优化设计,TMEH能获得更宽的采能带宽和更高的输出功率;2)TMEH比SMEH的采能效率有明显提高.在简谐振动激励和桥梁随机振动激励作用下,TMEH的输出功率比SMEH增加了约2倍.     

高陡横坡段桩柱式桥梁双桩基础受力分析

基于高陡横坡段桩柱式桥梁双桩基础承载特性,提出了一种改进有限杆单元计算分析方法.分析了高陡横坡段桩柱式桥梁双桩基础承载机理及受力特性,建立了双桩基础计算分析模型.其次,根据前、后桩与边坡相对位置关系,给出了后桩所受剩余下滑力与前桩所受土压力的比例关系.在传统有限杆单元分析方法基础上,结合陡坡桩受力特征,导得了考虑桩土共同作用与"P-Δ"效应的单元刚度矩阵修正方法,并在此基础上编制了适用于高陡横坡段桩柱式桥梁双桩基础的有限杆单元分析MATLAB计算程序.采用室内模型试验对本文计算方法进行验证,给出了适用于陡坡段桥梁桩基的设计流程图.研究结果表明:本文理论计算值与模型试验实测结果吻合良好,表明本文计算方法正确可行,可为同类工程设计提供参考.     

Lattice Solid/Boltzmann Microscopic Model to Simulate Solid/Fluid Systems-A Tool to Study Creation of Fluid Flow Networks for Viable Deep Geothermal Energy

SUMMARY:Realizing the potential of geothermal energy as a cheap, green, sustainable resource to provide for the planet’s future energy demands that a key geophysical problem be solved first:how to deve...     

融合多元触觉和沉浸式视觉的可移植VR软件框架

多元触觉和沉浸式视觉反馈的时空一致性配准以及现有VR软件框架中硬件设备的接入便捷性问题,制约了医疗、商务、娱乐等不同行业中视触觉融合场景的快速开发。为解决这一难题,提出融合多元触觉和沉浸式视觉的可移植VR软件框架,根据视触觉反馈精度要求的不同设计了双层和三层架构兼顾视觉渲染、触觉渲染、硬件控制的不同需求。实验结果表明该框架具有支持视-触融合同步反馈、硬件平台可移植、图形场景开发简便和交互场景可快速替换等特点,能够满足不同领域的交互应用需求。     

基于虚拟机的数据中心能耗测量

提出一种基于计算密集型与I/O密集型建立虚拟机动态能耗的数学模型方法.结合了设备运行状态参数，在模型功耗处于计算密集型时引入了虚拟机的CPU使用率与CPU频率，处于I/O密集型时引入了虚拟机的硬盘读写总字节数与内存读写总字节数计算功耗，并对功耗进行积分得出数据中心能耗.与常规方法相比该方法进一步细化了测量粒度，且在使用Wordcount运行任务与Sort运行任务进行节点能耗测试时，得出能耗的平均误差为0.062 5.实验结果在粒度细化的同时保证了常规方法的同级别测量精度.     

基于Flash交互动画技术的西湖传统文化保护系统

西湖传统文化保护系统属于非物质文化数字保护的范畴.在非物质文化数字化保护的框架下,以西湖传统文化内容为范例,探讨和建立了以Flash开发平台的Action Script 3.0为基础、交互动画形式为主的多维度交互式展示系统,重点解决基于Flash Action Script 3.0语言为基础的内在技术,尝试以模拟触控平台、无缝链接交互结构及自由信息交互操控三大交互结构设计来实现交互现实体验,从而验证了在数字化媒体艺术中Flash交互动画技术传播传统文化的优势和有效性.