A NEW DESCRIPA NEW DESCRIPTOR OF AMINO ACIDS BASED ON THE THREEDIMENSIONAL VECTOR OF ATOMIC INTERACTION FIELD

QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) IS A VERY IMPORTANT TOPIC FOR MANY SCIENTIFIC FIELDS AND CAN BE TERMED AS QUANTITATIVE SEQUENCE ACTIVITY MODELS(QSAM)[1] WHEN REFERRED TO THE RESEARCH ON RELATION- SHIPS BETWEEN STRUCTURES AND ACTIVITIES OF BIOLOGICAL MOLECULES, SUCH AS PROTEINS, AND NUCLEIC ACIDS. HOW- EVER, IT IS VERY DIFFICULT TO ESTABLISH A QSAM MODEL,…     

影响有机化合物酸碱强度的因素

主要从有机化合物的结构出发,分析和判断了电子效应、杂化方式及空间效应等因素对有机分子酸碱性的影响.     

杜仲氨基酸成份的研究

本文借助氨基酸自动分析仪对杜仲离体培养愈伤组织、树叶、树皮中氨基酸含量进行了系统研究，共检测出１６种氨基酸，其总含量为４１．４９～２０８．２２ｍｇ／ｇ，其中包括７种必需氨基酸。     

三种羟基羧酸气相色谱法的分离及定量分析

优化了α-羟基异丁酸、苹果酸、酒石酸的三种羟基羧酸与N，O-双(三甲基硅烷)三氟乙酰胺进行硅烷化反应的条件，建立了GC分离．外标法对各组分的分析结果表明，α-羟基异丁酸、苹果酸、酒石酸的回收率分别为98．1％、98．3％、97．3％；变异系数分别为1．5％、0．7％、1．6％．因此羟基羧酸硅烷化后，采用气相色谱法进行定量分析是完全可行的。     

Pathways for oxidative fuel provision to working muscles: Ecological consequences of maximal supply limitations

The study of metabolic fuel provision and its regulation has reached an exciting stage where specific molecular events can be correlated with parameters of the organism's ecology. This paper examines substrate supply pathways from storage sites to locomotory muscle mitochondria and discusses ecological implications of the limits for maximal flux through these pathways. The relative importance of the different oxidative fuels is shown to depend on aerobic capacity. Very aerobic, endurance-adapted animals such as long distance migrants favor the use of lipids and intramuscular fuels over carbohydrates and circulatory fuels. The hypothesis of functional co-adaptation between oxygen and metabolic fuel supply systems allows us to predict that the capacity of several biochemical processes should be scaled with maximal oxygen consumption. Key enzymes, transmembrane transporter proteins, glucose precursor supply and soluble fatty acid transport proteins must all be geared to support higher maximal glucose and fatty acid fluxes in aerobic than in sedentary species.     

Metabolism of 3β-hydroxycholest-5-en-26-oic acid in hamsters

Summary Metabolism of 26-hydroxycholesterol to 3-hydroxychol-5-en-24-oic acid and other C24-bile acids has been expected to occur by way of 3-hydroxycholest-5-en-26-oic acid in studies in vitro. 3-Hydroxycholest-5-en-26-oic acid was infused intravenously into bile fistula hamsters and the following C24-bile acids were identified: 3-hydroxychol-5-en-24-oic acid, lithocholic acid, chenodeoxycholic acid, and a small amount of cholic acid.     

鸭血烯酸对艾氏癌生长的抑制作用

鸭血烯酸是由鸭血清中提取的不饱和脂肪酸．在体外实验中具有使艾氏腹水癌细胞膨胀失活的作用．用于治疗艾氏癌患鼠,可抑制其腹水癌和实体瘤的生长．与环磷酰胺（CPA）或氟脲嘧啶（SFU）相比,鸭血烯酸的毒性较低,疗效较高,约20％～40％被治愈的患鼠,可长期存活．     

蛇油中脂肪酸成分的GC—MS研究

用溶剂热抽提蛇油脂肪和ＫＯＨ／甲醇酯交换甲酯化,以气相色谱－质谱联用技术测定脂肪酸组成,鉴定了２９种脂肪酸成分,其中含量较高的成分有肉豆蔻酸,棕榈油酸,棕榈酸,亚油酸,油酸,硬脂酸,花生四烯酸,二十碳三烯酸,二十碳二烯酸,二十二碳四烯酸等．蛇油中不饱和脂肪酸的含量占脂肪酸总量的６３％以上．     

非饱和分层土壤中污染物迁移转化规律研究

分析了污染物在分层土壤中随下渗水体向下迁移的机理过程,借助于数值计算模型模拟计算非饱和分层土壤中污染物迁移转化特性,研究了不同土壤层及土壤层的排序对污染物迁移转化的影响状况。     

非饱和带溶质运移问题的有限元解法

ＳＵＰＧ有限元法应用于土体的非饱和溶质运移问题,导出了其数值表达式,编制了计算程序。以一维入渗问题为例进行了数值计算,与其他方法及野外试验结果进行了对比,表明该方法是正确的、稳定的,可用于非饱和带溶质运移问题的实际计算。