两耳分听汉字测验中大脑机能优势加工的超日节律效应

对３２名听力正常的大学生被试在日间进行连续８ｈ汉语单字词两耳分听测验,以检查大脑两半球加工汉字语音机能优势的时间性动态变化。结果发现：①所有被试左、右耳正确报告的词数未见有明显的周期性波动;②有１２例被试左、右耳正确占先报告词数的优势比出现了周期约为３ｈ的超日节律;③女性被试的平均节律周期长度明显长于男性。结果提示,大脑两半球控制的分听语词加工过程在部分被试中明显受到生物钟超日节律的调节。     

胎儿大脑左右两半球Broca氏区皮质组织结构的比较

取4至10月龄的胎儿大脑两半球Broca氏区的皮质进行组织学切片，染色、显微镜观察，比较各月龄胎儿大脑左右两半球Broca氏区的皮质厚度，第Ⅲ层锥体细胞的体积和密度，发现各月龄胎儿左右两半球Broca氏区皮质厚度及其第Ⅲ层锥体细胞密度无显著性差异；锥体细胞的体积在8、9月龄胎儿左右半球无显著性差异，但10月龄则左半球的大于右半球。     

Neurotrophic effects of conditioned media of astrocytes isolated from different brain regions on hippocampal and cortical neurons

The present study was designed to reveal whether astroglial cells from different brain regions produce diffusible factors that differentially support the survival of neurons and the establishment of neuronal morphology. For this purpose, astrocyte conditioned media (ACM) were prepared by conditioning chemically-defined medium with type I astrocyte culture dissociated from cerebral cortex, hippocampus and hypothalamus. Hippocampal and cortical neurons were cultured in ACM or in non-conditioned medium. ACM derived from three brain regions all supported the survival of hippocampal and cortical neurons better than non-conditioned control medium. Of these, hypothalamic ACM was the most effective in supporting the survival of cortical neurons. The ACM also potentiated the elongation of the longest neurite of hippocampal and cortical neurons. However, there were no significant differences in the promoting effects on neurite elongation among ACM from three brain regions.     

Difference of the inhibitory action of verapamil on the positive inotropic effect of Ca2+ between spontaneously hypertensive and normotensive rat myocardium

Summary Verapamil, a calcium entry blocker, had a greater inhibitory effect on the positive inotropic effect of excess Ca²⁺ in SHR than in NWR, suggesting that the cardiac responsiveness to verapamil was enhanced in SHR.     

高血压脑出血手术时机与适应证的探讨

根据对118例高血压性脑出血立体定向外科手术治疗的总结，强调高血压性脑出血一经诊断，且具有手术指征时，手术越早越好；且认为患者的意识障碍严重程度、出血量、出血部位、发病时血压以及病人的年龄等因素对选择手术时机和手术适应证具有重要价值，并提出了具体的手术指征．     

Atrial natriuretic factor in hypovolemic tachycardia

Summary Atrial natriuretic factor (ANF) is released in response to many stimuli which increase right atrial pressure. Following hemorrhage pigs lowered their atrial pressures, developed a tachycardia and increased ANF levels. Electrical pacing increased heart rate and ANF levels. There is a stimulus to ANF release other than atrial stretch, probably heart rate.     

多层重叠薄块和最佳倾斜非饱和激发磁共振血管造影在脑动静脉畸形诊断中的应用

目的：分析脑动静脉畸形(arteriovenous malformations，AVM)的三维时间飞越法磁共振血管造影(3D-Time of Hight Magnetic Resonance Angiography，3D-TOFMRA)结合多层重叠薄块(multiple overlapping thin slab acquisition，MOTSA)和最佳倾斜非饱和激发(tilted optimized nonsaturating excitation，TONE)技术的磁共振成像表现，探讨其应用价值。方法：对150例AVM患分别行SE序列磁共振成像(MRI)，3D-TOF MRA结合MOTSA和TONE检查。结果：MR／及3D-TOF MRA都能显示AVM的瘤巢，AVM的继发改变MRI能很好地显示，MRA能显示AVM的三维解剖结构。结论：MOTSA结合TONE MRA是无创性评价脑AVM的有效方法，结合MRI可提高诊断准确率，为临床治疗方案的选择提供帮助并能对治疗效果进行客观评价。     

物质信息与大脑意识

从普通物理学的领域提出了一般信息的概念 ,并对有关信息进行了分类。阐述了基层宇宙信息与基层生物信息的联系和区别。在此基础上对人体神经信息与大脑意识作出了可能的解释 :意识是引导大脑皮质特殊活动的复杂信息。最后 ,讨论了关于物质信息的认识论和辩证法意义。     

微创手术治疗高血压引发脑出血99例临床观察

目的 探讨微创颅内血肿清除术治疗高血压脑出血的临床效果.方法 对2006年患高血压脑出血、出血量在30 mL以上的45例患者,行微创颅内血肿清除术与内科保守治疗的54例患者分两组对比治疗效果.结果 两组治疗统计结果 有显著差异.结论 微创颅内血肿清除术技术操作简单,损伤轻,能最大限度地解除患者病变的恶性循环,保留患者的生理功能,显著降低患者死亡率和致残率,提高生存质量,是目前临床治疗脑出血比较理想的方法 .     

高血压脑出血的病理生理机制

高血压脑出血是急性脑血管病中死亡率和致残率很高的一种疾病.高血压病可导致全身器官血管的病理性改变,深入研究高血压脑出血的发病机制和病理生理机制有助于对该疾病的认识,并对临床治疗有一定的理论指导意义.现就高血压脑出血的发病、对脑组织的损伤等病理生理机制内容综述如下.