二维铜(Ⅱ)配位聚合物{[Cu(1,3-bip)(1,3-bdc)]·H_2O}_n的合成、晶体结构及热稳定性研究

以1,3-bip(1,3-二咪唑丙烷)、1,3-bdc(间苯二甲酸)和Cu(NO3)2·3H2O为原料,在水热条件下合成了二维铜(Ⅱ)配位聚合物{[Cu(1,3-bip)(1,3-bdc)]·H2O}n,并用元素分析、红外光谱、X-射线单晶衍射对配合物进行了表征.测定结果表明,晶体属三斜晶系,P-1空间群,晶胞参数:a=0.910 50(5)nm,b=1.004 65(7)nm,c=1.154 67(6)nm,α=84.924(5)°,β=89.444(4)°,γ=76.505(5)°.标题配合物中每个Cu(Ⅱ)离子作为一个四连接的节点,通过1,3-bdc和1,3-bip桥联连接形成了二维(4,4)网格结构.此外,通过热重分析研究该配合物的热稳定性.     

高校大型仪器设备管理现状的分析与思考

高校大型仪器设备是高校从事教学、科研的重要保障条件,是衡量其教学条件、科研能力和社会服务能力的重要标志之一。通过对天津市部分高校的走访调查,就当前高校大型仪器设备管理的现状,从制度建设、大型仪器使用团队建立、共享平台建设及大型仪器联合使用等方面提出了相应的建议,籍此保障教学资源的充分利用,提高大型仪器的使用效益。     

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

Resolution of acute inflammation is an active process essential for appropriate host responses, tissue protection and the return to homeostasis. During resolution, specific omega-3 polyunsaturated fatty-acid-derived mediators are generated within resolving exudates, including resolvin E1 (RvE1) and protectin D1 (PD1). It is thus important to pinpoint specific actions of RvE1 and PD1 in regulating tissue resolution. Here we report that RvE1 and PD1 in nanogram quantities promote phagocyte removal during acute inflammation by regulating leukocyte infiltration, increasing macrophage ingestion of apoptotic polymorphonuclear neutrophils in vivo and in vitro, and enhancing the appearance of phagocytes carrying engulfed zymosan in lymph nodes and spleen. In this tissue terrain, inhibition of either cyclooxygenase or lipoxygenases--pivotal enzymes in the temporal generation of both pro-inflammatory and pro-resolving mediators--caused a 'resolution deficit' that was rescued by RvE1, PD1 or aspirin-triggered lipoxin A4 analogue. Also, new resolution routes were identified that involve phagocytes traversing perinodal adipose tissues and non-apoptotic polymorphonuclear neutrophils carrying engulfed zymosan to lymph nodes. Together, these results identify new active components for postexudate resolution traffic, and demonstrate that RvE1 and PD1 are potent agonists for resolution of inflamed tissues.     

Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis

Intestinal epithelial cells (IECs) provide a primary physical barrier against commensal and pathogenic microorganisms in the gastrointestinal (GI) tract, but the influence of IECs on the development and regulation of immunity to infection is unknown. Here we show that IEC-intrinsic IkappaB kinase (IKK)-beta-dependent gene expression is a critical regulator of responses of dendritic cells and CD4+ T cells in the GI tract. Mice with an IEC-specific deletion of IKK-beta show a reduced expression of the epithelial-cell-restricted cytokine thymic stromal lymphopoietin in the intestine and, after infection with the gut-dwelling parasite Trichuris, fail to develop a pathogen-specific CD4+ T helper type 2 (T(H)2) response and are unable to eradicate infection. Further, these animals show exacerbated production of dendritic-cell-derived interleukin-12/23p40 and tumour necrosis factor-alpha, increased levels of CD4+ T-cell-derived interferon-gamma and interleukin-17, and develop severe intestinal inflammation. Blockade of proinflammatory cytokines during Trichuris infection ablates the requirement for IKK-beta in IECs to promote CD4+ T(H)2 cell-dependent immunity, identifying an essential function for IECs in tissue-specific conditioning of dendritic cells and limiting type 1 cytokine production in the GI tract. These results indicate that the balance of IKK-beta-dependent gene expression in the intestinal epithelium is crucial in intestinal immune homeostasis by promoting mucosal immunity and limiting chronic inflammation.     

氢化物发生无色散原子荧光分析法测定水中的砷和硒的含量

采用断续流动氢化物发生无色散原子荧光分析法同时测定水中的微量砷、硒,确定了仪器及氢化物产生的最佳实验条件。测定结果表明实际样品中砷的回收率在85%~110%之间;硒的回收率在92%~102%之间,样品测量值的相对标准偏差砷在1.1%~4.8%之间,硒在5.0%~5.9%之间。本方法可一次消化样品并同时测定砷、硒的含量,具有操作简单、快速、基体干扰少、灵敏度高、分析结果稳定可靠、节省试剂等特点,并且采用自动进样,适于大量样品的快速分析。     

一种新的解锁螺栓分离时间测试方法

基于激光位移传感器测试解锁螺栓分离时间的思想,设计一种新的解锁螺栓分离时间测试方法,并设计了相应的测试系统,其测试不确定度为0.184%.通过试验得到新方法测得解锁螺栓分离时间平均值14.74ms,传统的通-断靶线法测得分离时间平均值14.60ms,三次试验均值相差0.14ms.结果表明,新方法不仅能直接有效地测试解锁螺栓分离时间,还能间接地表征解锁螺栓的分离速度、冲击加速度以及分离冲量等分离特性参数.     

Response of the northwestern Pacific upper water δ~(13)C to the last deglacial ventilation of the deep Southern Ocean

The deglacial δ~13C minimum events that originated from the ventilation of the deep Southern Ocean around Antarctica, have been recorded in a range of marine sediments from the southern to tropical oceans in late Pleistocene. However, the broad δ~13C minimum event was also reported as far as to the northern middle latitudes, in northwestern Pacific marginal sea areas, during the last deglaciation. In the northwestern Pacific, forcing from the northern high latitudes is strongly expressed, while the records of in- fluence from the southern high latitudes are few. The Kuroshio Source Region (KSR) forms a boundary between the northwestern Pacific and the southern, tropical Pacific. So, high-resolution planktonic foraminiferal records in core MD06-3054 from the KSR are well positioned to identify signals from the southern hemisphere in the northwestern Pacific. Planktonic foraminiferal tests from the upper 1030 cm of the core were subject to AMS14C, carbon and oxygen isotopic measurements. A negative excursion was found to occur from about 20.0-6.0 ka BP in δ~13C records of both surface (Globigerinoides ruber) and subsurface (Pulleni- atina obliquiloculata) dwellers, but the overall trends of the two curves have reversed since 26.5 ka BP. Moreover, the δ~13C rec- ord of G. ruber (the surface dweller) shows a robust link to the record of atmospheric CO2, and its changes precede the records of P. obliquiloculata (the subsurface dweller). According to the hydrologic conditions, the broad δ~13C minimum event recorded in the KSR is also a response to the increasing ventilation of the deep Southern Ocean around Antarctica during the last deglaciation. The inconsistency between the records of the surface and subsurface dwellers was possibly caused by the ways that the low δ~13C signal was transmitted. Subsurface water primarily received the low δ~13C signal from the Antarctic Intermediate Water (AAIW), whereas the surface water was probably mainly impacted by atmospheric CO2 in the KSR. The records from the KSR confirm the deduction that the broad δ~13C minimum event in the Okinawa Trough was due to the impact of tropical Pacific surface water dur- ing the last deglaciation, and suggest that signals from the southern high latitudes also can be delivered to the northern middle latitudes.     

基于邻域粗糙集的不完整决策系统特征选择算法

针对不完整决策系统属性约简算法时间复杂度较高问题,基于正域不变条件下,决策系统分类能力保持不变原则,提出不完整决策系统前向顺序特征选择算法.该算法从约简集为空集开始,根据在约简集合中加入各属性后对正域影响程度大小将属性降序排列,采用顺序前向搜索,选择当前最佳特征加入特征约简集合,确定最佳特征子集.将该算法扩展到基于邻域...     

宽带认知无线电网络分布式协作压缩频谱感知算法

针对宽带认知无线电网络中压缩频谱感知算法在低信噪比环境下频谱检测性能下降的问题,提出了一种基于高斯过程的分布式压缩频谱感知(PBCS)算法.首先应用层次化的正态分布概率模型来表示压缩频谱的重构,然后各个认知无线电用户交换模型参数并结合本地的压缩采样数据进行压缩频谱感知.有别于其他直接融合频谱感知结果或检测数据的协作式算法,PBCS算法通过模型参数融合来进行协作,能有效减小信噪比低的协作用户的影响,从而提高算法的抗噪性.仿真结果表明,PBCS算法可以在-5dB的信噪比条件下达到检测概率大于0.9、误检概率为0.1的频谱检测性能.