C-banding pattern and nucleolar organizer regions of Cynoglossus semilaevis Günther, 1873

The C-banding pattern and nucleolar organizer regions of the metaphase chromosomes of Cynoglossus semilaevis are reported. The interstitial regions in all chromosomes including the pair of sex chromosomes had positive C-bands, and the 6th and 12th pairs of chromosomes were entirely stained in most cases. Some chromosomes such as the 1st, 2nd, 7th, 8th, 9th and 10th pairs showed C-bands at centromeric or distal ends. The C-banding heretochromatin occupies 30.03% of the total chromosome surface in C. semilaevis,which is similar to that of amphibians such as Mixophyes fasciolatus (30.2%) and M. schevilli (20.7%), but is rather lower than that of cephalochordate Branchiostoma belcheri (54.3%). Silver staining revealed a single pair of nucleolar organizer regions (NORs) located in the telomeric regions of Chromosome 2. The association of NORs with heterochromatin observed in vertebrates also occurs in C. semilaevis as the telomeric regions of Chromosome 2 are always stained positively with C-banding.     

合成N,N,N'''',N''''-四(2-甲酯基乙基)乙二胺的绿色工艺研究

为了解决合成聚酰胺-胺时回收液处理复杂、能耗大、并污染环境的问题,以合成N,N,N',N'-四(2-甲酯基乙基)乙二胺(TMCEDA)为研究对象,对不同真空度条件下的回收液进行了定性定量分析,在此基础上,采用分段减压蒸馏分离合成TMCEDA中的过量原料与溶剂,直接循环使用真空度在50 kPa-100 kPa的回收液的新工艺.应用气相色谱分析技术跟踪分析循环使用的回收液的成分,结果表明,经过40次循环使用的回收液,仍未见明显的杂质积累现象.该工艺对回收液的直接使用率高达98.0%,实现了TMCEDA的实验室绿色合成,可为其工业化生产提供参考.图7,表2,参11.     

局部复发性直肠癌的再手术治疗

探讨局部复发性直肠癌(直肠癌根治术后)再次手术的价值、方法、回顾性分析再手术治疗的局部复发性直肠癌33例.结果:21例行根治术,12例行姑息性手术.根治术组和姑息性手术组中位生存期分别为35.2个月(8～82个月)、13个月(2～23个月),再手术5年生存率为34.8%.结论:对于局部复发性直肠癌仍应积极手术,有助于延长生存期,提高生存质量.     

双DC-DC变换器在爆闪式警示信号灯上的应用

本文探讨利用双DC-DC变换器去解决单级DC-DC变换器在宽电压范围工作时开关效率降低,开关器件不能正常工作,甚至损坏的问题。在现有信号灯的基础上,设计出一种寿命长、适应宽电压范围、功能齐全,便于生产、管理、使用、维修的爆闪式警示信号灯。     

任务驱动教法在计算机教学中的应用

任务驱动教法是众多教学方法中的一种,本文先探讨了计算机教学中任务驱动教法的必要性,然后详细阐述了任务驱动教法的含义及其实施过程,最后说明了使用任务驱动教法时应注意的问题。     

基于时延脉冲耦合神经网络的AOE-网问题求解算法

 在时延脉冲耦合神经网络(DPCNN-Delay Pulse Coupled Neural Network)的基础上,提出了mDPC-NN(modified DPCNN)模型.mDPCNN能方便地用于有向网的最大代价路径和最小代价路径的求解,并将其成功地运用其于求解AOE-网(Activity On Edge)有关问题.该方法通过快速并行计算,一次正向计算即可求解AOE-网大部分问题,与传统方法相比体现了较好的优势.     

Finding finer functions for partially characterized proteins by protein-protein interaction networks

Based on high-throughput data, numerous algorithms have been designed to find functions of novel proteins. However, the effectiveness of such algorithms is currently limited by some fundamental factors, including (1) the low a-priori probability of novel proteins participating in a detailed function; (2) the huge false data present in high-throughput datasets; (3) the incomplete data coverage of functional classes; (4) the abundant but heterogeneous negative samples for training the algorithms; and (5) the lack of detailed functional knowledge for training algorithms. Here, for partially characterized proteins, we suggest an approach to finding their finer functions based on protein interaction sub-networks or gene expression patterns, defined in function-specific subspaces. The proposed approach can lessen the above-mentioned problems by properly defining the prediction range and functionally filtering the noisy data, and thus can efficiently find proteins’ novel functions. For thousands of yeast and human proteins partially characterized, it is able to reliably find their finer functions (e.g., the translational functions) with more than 90% precision. The predicted finer functions are highly valuable both for guiding the follow-up wet-lab validation and for providing the necessary data for training algorithms to learn other proteins.     

三维光盘存储系统中双光头同步控制的频域分析与辨识

详细介绍了双光头同步控制原理.对采集的伺服模块聚焦误差跟踪信号及共焦模块读写光头的聚焦线圈驱动信号进行了频域分析,并以此两路信号作为系统输入输出,分别对三种参数模型进行参数优化.根据3种模型的频率响应及阶跃响应,选择双光头同步控制过程的参数模型为[450]阶的ARX模型.实测曲线与模型仿真结果符合度(fit)为78.0259%.     

信息技术环境下儿童语言发展促进研究

在儿童语言发展特征与人类语言习得理论的基础上,探讨信息技术环境下,利用信息技术促进儿童口语、书面语发展的方法和策略以及要注意的问题。     

树立地方文献品牌建设地方特色馆藏——公共图书馆地方文献的开发和利用

介绍了公共图书馆地方文献的收藏特色,论述了树立地方文献品牌的途径,提出了全面开发地方文献资源的建议。