采场人员可靠性模糊综合分析

针对采场人—机—环境可靠性系统中,人是最主要的也是最脆弱的这一特点,根据可靠性理论,应用模糊数学理论与层次分析法,建立了一种新型的系统可靠性模糊数学分析模型,对采场人员可靠性进行综合分析和评价。该分析方法能够对采场人员系统可靠性给以直观、定量的描述。最后,以某磷矿为例,验证了模型的合理性。     

Telomeres and meiosis in health and disease

Telomeres are important segments of chromosomes that protect chromosome ends from nucleolytic degradation and fusion. At meiosis telomeres display an unprecedented behavior which involves their attachment and motility along the nuclear envelope. The movements become restricted to a limited nuclear sector during the so-called bouquet stage, which is widely conserved among species. Recent observations suggest that telomere clustering involves actin and/or microtubules, and is altered in the presence of impaired recombinogenic and chromosome related functions. This review aims to provide an overview of what is currently known about meiotic telomere attachment, dynamics and regulation in synaptic meiosis.     

巷旁充填沿空留巷技术研究

本文通过转Ⅳ喷射机组成的风力充填系统输送矸石——水泥胶凝混合料的巷旁充填研究,介绍了该技术在沿空留巷中应用及效果,并对改进提出了建议。     

大学生口算能力的实验研究

为考察大学生的口算能力,我们随机选取30名大学生为被试进行口算的实验研究,主要结论如下:(1)大学生的口算速率在加、减、乘、除法之间存在差异,从快到慢依次为:除法,借位减法,不借位减法,不进位加法,进位加法,乘法;(2)口算的广度从大到小依次为:不进位的加法广度,进位加法广度,不借位减法广度,借位减法广度,除法广度,乘法广度;(3)大学生口算的速度和广度既无显著的专业差异,也无显著的性别差异.     

矿井瓦斯来源分析

从矿井瓦斯的来源、瓦斯的运移及运移参数,表明上邻近层是回采面瓦斯的主要来源,指出瓦斯抽放是治理瓦斯的治本措施。     

The cold case: Are rhinoviruses perfectly adapted pathogens?

Rhinoviruses, which cause common cold, belong to the Picornaviridae family, small non-enveloped viruses (diameter 15-30 nm) containing a single-stranded RNA genome (about 7 kb). Over 100 different rhinoviral serotypes have been identified thus far, establishing rhinoviruses as the most diverse group of Picornaviridae. Based on receptor binding properties, rhinoviruses are divided into two classes: the major group binding to intracellular adhesion molecule-1 and the minor group binding to the very low density lipoprotein receptors. Interactions between virus and the receptor molecules cause a conformational change in the capsid, which is a prerequisite for viral uptake. Rhinoviruses trigger a chemokine response upon infection that may lead to exacerbation of the symptoms of common cold, i.e. asthma and inflammation. The following review aims to summarize the knowledge about rhinoviral infections and discusses therapeutical approaches against this almost perfectly adapted pathogen.     

From endoderm to pancreas: a multistep journey

The formation of the vertebrate pancreas is a complex process that typifies the basic steps of embryonic development. It involves the establishment of competence, specification, signaling from neighboring tissues, morphogenesis, and the elaboration of tissue-specific genetic networks. A full analysis of this multistep process will help us to understand classic principles of embryonic development. Furthermore, this will provide the blueprint for experimental programming of pancreas formation from embryonic stem cells in the context of diabetes cell-therapy. Although in the past decade many studies have contributed to a solid foundation for understanding pancreatogenesis, important gaps persist in our knowledge of early pancreas formation. This review will summarize the current understanding of the early mechanisms coming into play to pattern the "pre-pancreatic" region within the endoderm and, gradually, specify the pancreatic tissue.     

Comparative aspects of structure and action of molluscan neuropeptides

A number of neuropeptides were isolated from the ganglia and muscles of molluscs, and their actions were examined. Diverse neuropeptides, in addition to several classical neurotransmitters, were suggested to be involved in the regulation of the anterior byssus retractor muscle ofMytilus. A wide structural variety of members of theMytilus inhibitory peptide family was observed in each of the generaMytilus, Achatina andHelix. Gly-Trp-NH₂, the C-terminal dipeptide fragment of the neuropeptide AGPWamide, showed a more potent action than the parent peptide in all of the muscles examined. Peptides related to some molluscan neuropeptides were found to be distributed interphyletically. Some neuropeptides containing ad-amino acid residue were found inAchatina andMytilus. These aspects of molluscan neuropeptides are thought not to be exceptional.     

钢琴教学的第一步--提高视谱能力

高等师范音乐专业的扩招以及入学新生普遍音乐基础差的现状,给高师音乐教育的质量带来直接的影响。钢琴课作为一门重要课程,如何以新的对策,对音乐基础差的、甚至不识谱的学生施教,在钢琴必修课的短暂的两年中尽可能获得更好的教学效果,是钢琴教学面临的既紧迫又艰巨的研究课题。开设视唱强化训练课程能迅速提高学生的视谱能力、对乐谱的分析能力,是提高钢琴教学效果,保证高师音乐教育质量的有效措施。