玉米须蚕茧提取物对糖尿病模型小鼠血糖的影响

目的探讨玉米须蚕茧提取物对糖尿病小鼠模型的降糖作用.方法采用尾静脉注射小剂量的四氧嘧啶造小鼠糖尿病模型,观察不同剂量的玉米须蚕茧提取物对小鼠血糖的影响.结果玉米须蚕茧提取物对该模型有较好的降糖作用,低剂量组血糖质量浓度为(139.46±40.97)cg/L,中剂量组血糖质量浓度为(142.00±46.65)cg/L,高剂量组血糖质量浓度为(144.23±36.89)cg/L,给药组血糖均与模型组血糖有显著差别(P0.05).结论玉米须蚕茧提取物对本糖尿病模型有较好的治疗作用.     

天尖茶对糖尿病小鼠的降血糖作用研究

以腹腔注射四氧嘧啶诱导糖尿病的小鼠作为试验模型,选取天尖茶进行糖尿病治疗实验,设立天尖茶水提物高剂量组和天尖茶水提物低剂量组,并以空白组、模型组和喂食治疗药物二甲双胍的阳性药组,通过小鼠体重及日进食量变化,空腹血糖值,血清中INS、TC、TG浓度以及肝体比,对各组小鼠的治疗效果进行检测.研究结果表明,天尖茶有明显治疗小鼠糖尿病效果.高剂量天尖茶在使糖尿病小鼠多食、多尿、消瘦症状减轻,降低糖尿病小鼠血糖浓度、提升血清中INS浓度、降低TC、TG浓度上效果要明显优于低剂量天尖茶,与二甲双胍的治疗效果接近.研究结果表明:天尖茶内均含有大量具有降糖作用的活性化合物.     

紫球藻胞外多糖对四氧嘧啶糖尿病小鼠血糖的调节作用

通过尾静脉注射四氧嘧啶建立小鼠糖尿病模型,分别用紫球藻胞外多糖按每kg体质量300 m g和150 m g灌胃给药,连续21 d后,分别测定空腹12 h血糖和血浆SOD活性,并观察各组小鼠胰脏组织结构.实验结果显示,与糖尿病模型组相比,紫球藻胞外多糖组小鼠的血糖显著降低(P<0.05),小鼠血浆SOD活性显著升高(P<0.05);紫球藻胞外多糖组小鼠胰脏中胰岛形态结构正常,无纤维化,无出血坏死和明显的炎症细胞浸润.结果表明紫球藻胞外多糖能降低四氧嘧啶糖尿病小鼠血糖并呈现一定的抗氧化能力,对四氧嘧啶所致小鼠胰岛细胞损伤具有修复作用.     

生姜醇提物对糖尿病小鼠肾损害保护作用的研究

目的:探讨生姜醇提物对糖尿病小鼠肾损害的保护作用。方法:将30只KM种雄性小鼠随机分为三组,正常对照组(C组,n=10)、模型组(DM组,n=10)及生姜醇提物干预组(ZGB组,n=10)。DM组及ZGB组小鼠尾静脉注射2%四氧嘧啶(90 mg/kg)建立糖尿病肾损害模型。造模成功后,ZGB组给予生姜醇提物溶液0.5 mL(300 mg/kg.d)灌胃14 d,DM组及C组给予生理盐水灌胃。14 d后小鼠断头取血,测定血糖、血清肌酐、尿素氮含量,检测肾组织丙二醛(MDA)及超氧化物歧化酶(SOD)活力的变化,光镜下观察肾组织病理学改变。结果:与DM组比较,ZGB组血糖、血肌酐及尿素氮水平明显低于DM组(P<0.01);肾组织MDA含量明显低于DM组(P<0.01),而T-SOD活力则较DM组升高(P<0.01)。光镜下ZGB组肾脏组织形态学的异常改变较模型组减轻。结论:生姜醇提物对糖尿病小鼠的肾损害有一定的保护作用。     

峨眉山猕猴桃粗提物的降血糖作用

通过尾部静脉注射四氧嘧啶水溶液60 mg/kg建立实验性糖尿病小鼠模型，探究猕猴桃水、醇提取物及其混合物对实验性糖尿病小白鼠的降血糖作用。研究结果表明，三种猕猴桃提取物对糖尿病小白鼠均有极显著的降血糖作用，猕猴桃水提物、醇提物、水醇提取物混合物的平均降糖率分别为30.03%、18.28%、22.50%，其降糖活性成分主要为水溶性物质。     

松针提取物降糖作用的实验研究

目的观察松针提取物(Pineneedle Extract,PNE)的降糖作用.方法通过给小鼠连续灌胃松针提取物,观察其对正常小鼠血糖以及对肾上腺素和四氧嘧啶引起的高血糖小鼠血糖的影响.结果松针提取物200,400,800 mg/kg对正常小鼠的血糖水平无明显影响,但均可降低由肾上腺素和四氧嘧啶引起的高血糖小鼠的血糖,且呈现良好的剂量依赖性.结论松针提取物具有显著的降血糖作用.     

免疫初乳对正常和实验性糖尿病小鼠血糖的影响

目的研究免疫初乳对正常小鼠和四氧嘧啶致糖尿病小鼠血糖的影响.方法用正常小鼠和糖尿病模型小鼠研究免疫初乳调节血糖的作用.连续30d给予正常小鼠和四氧嘧啶糖尿病模型小鼠免疫初乳,30d后眼眶取血,取其血清测定小鼠空腹血清血糖.结论免疫初乳能显著降低四氧嘧啶致高血糖小鼠的血糖水平并提高其糖耐量,且高剂量免疫初乳组的效果好于低剂量组的效果.但免疫初乳对正常小鼠的血清血糖及糖耐量没有影响.     

胶原蛋白多肽-铬(Ⅲ)螯合物对四氧嘧啶诱发小鼠糖尿病的保护作用

研究胶原蛋白多肽-铬（Ⅲ）螯合物对四氧嘧啶诱发小鼠糖尿病的保护作用。通过腹腔注射四氧嘧啶造小鼠糖尿病模型，观察胶原蛋白多肽-铬（Ⅲ）螯合物对糖尿病小鼠糖代谢（空腹血糖）及脂代谢（甘油三酯，胆回醇，高密度脂蛋白胆固醇，低密度脂蛋白胆固醇）的影响。实验结果表明，胶原蛋白多肽-铬（Ⅲ）螯合物显著降低糖尿病小鼠空腹血糖、甘油三酯、胆固醇和低密度脂蛋白胆固醇水平。提高高密度脂蛋白胆固醇水平。说明胶原蛋白多肽-铬（Ⅲ）螯合物对四氧嘧啶诱发的小鼠糖尿病具有显著的保护作用。     

玉米特强粉对糖尿病模型小鼠血糖的影响

目的研究玉米特强粉对糖尿病模型小鼠血糖的影响,为玉米深加工食品的开发提供前提依据.方法玉米特强粉低剂量组(含量20%)和高剂量组(含量60%),连续喂食22 d,对正常小鼠葡萄糖耐量的影响;玉米特强粉对肾上腺素性高血糖模型小鼠血糖的影响;玉米特强粉对四氧嘧啶(Alloxan)诱发的高血糖模型小鼠血糖的影响.结果玉米特强粉对正常小鼠葡萄糖耐量无明显影响;高、低剂量组对肾上腺素性高血糖模型小鼠及四氧嘧啶诱发的糖尿病模型小鼠均具有明显的降血糖作用(P<0.05).结论玉米特强粉对正常小鼠葡萄糖耐量无明显影响;对肾上腺素性高血糖模型小鼠及四氧嘧啶诱发的糖尿病模型小鼠具有明显的降血糖作用.     

平卧菊三七提取物降血糖实验研究

目的:观察平卧菊三七提取物对四氧嘧啶型糖尿病小鼠的降糖作用.方法:选用22~26 g雄性ICR小鼠,禁食时间16 h,腹腔注射200 mg/kg四氧嘧啶造模.结果:连续给药14 d,各组均具有明显降糖效果,且能明显改善小鼠多饮多食症状.结论:平卧菊三七提取物能很好地抑制糖尿病小鼠血糖升高,改善多饮多食症状,疗效与剂量无明显线性关系.     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

A computer generator for randomly layered structures

AcomputergeneratorforrandomlylayeredstructuresYUJia shun1,2,HEZhen hua2(1.TheInstituteofGeologicalandNuclearSciences,NewZealand;2.StateKeyLaboratoryofOilandGasReservoirGeologyandExploitation,ChengduUniversityofTechnology,China)Abstract:Analgorithmisintrod…     

An Index mechanism for multi-scale view in spatial databases

There are numerous geometric objects stored in the spatial databases. An importance function in a spatial database is that users can browse the geometric objects as a map efficiently. Thus the spatial database should display the geometric objects users concern about swiftly onto the display window. This process includes two operations:retrieve data from database and then draw them onto screen. Accordingly, to improve the efficiency, we should try to reduce time of both retrieving object and displaying them. The former can be achieved with the aid of spatial index such as R-tree, the latter require to simplify the objects. Simplification means that objects are shown with sufficient but not with unnecessary detail which depend on the scale of browse. So the major problem is how to retrieve data at different detail level efficiently. This paper introduces the implementation of a multi-scale index in the spatial database SISP (Spatial Information Shared Platform) which is generalized from R-tree. The difference between the generalization and the R-tree lies on two facets: One is that every node and geometric object in the generalization is assigned with a importance value which denote the importance of them, and every vertex in the objects are assigned with a importance value,too. The importance value can be use to decide which data should be retrieve from disk in a query. The other difference is that geometric objects in the generalization are divided into one or more sub-blocks, and vertexes are total ordered by their importance value. With the help of the generalized R-tree, one can easily retrieve data at different detail levels.Some experiments are performed on real-life data to evaluate the performance of solutions that separately use normal spatial index and multi-scale spatial index. The results show that the solution using multi-scale index in SISP is satisfying.     

Jane Eyre——A Feminist In The 19th Century

In the 19th century the society was controlled by men, and women were just appendants of them, they had not any rights and freedom. But Jane was an exception, she showed some characteristics of early feminist. Jane showed her characteristics of feminism in three aspects: rebellion, equality, and independence. These characteristics were helpful to her success, and feminism is the only way out for women of that time.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-