超声激活血卟啉杀伤癌细胞的扫描电镜观察

利用频率为2MHz,强度为0．9W／cm^2的超声(Ultrasound,US)激活血卟啉(Hematoporphyrin deriVatives,HpD)对在体的腹水型艾氏腹水瘤细胞(Ehrlich Ascites Tumor,EAT)和S180(Sarcomal80,S180)细胞进行抑癌作用研究。通过扫描电子显微镜观察处理后细胞形态的变化,结果表明：超声激活血卟琳对艾氏腹水瘤细胞和S180细胞均有明显的杀伤效果,且通过对损伤不同形态的比较,得出S180细胞膜较艾氏腹水瘤细胞膜对于声动力疗法(Sonodynamic Therapy,SDT)更为敏感。     

基于波动理论消除表层多次波

基于波动理论和Berkhout的反馈模型,可通过反馈回路的物理系统产生包括多次波的地震记录,并可表示为一组第二类积分方程。首先通过原始记录与一次波的初始估计值(可以是炮记录本身)的空间褶积预测多次波,再用最小能量准则反演求得的表层算子的逆来标定多次波,最后从原始记录中将多次波消除。整个预测过程无须知道宏观速度场,增强了预测方法的适应性。为更好地消除表层多次波,应采用迭代反演的方法。理论模型试算和实际资料试处理的结果表明,该方法对表层多次波有较好的压制作用,一般只需2～3次迭代即可。其处理效果要优于拉冬变换法,对100炮左右的常规数据来说,一次迭代一般需要30min左右。     

基于波动理论消除表层多次波

基于波动理论和Perkhout的反馈模型,可通过反馈回路的物理系统产生包括多次波的地震记录,并可表示为一组第二类积分方程。首先通过原始记录与一次波的初始估计值(可以是炮记录本身)的空间褶积预测多次波,再用最小能量准则反演求得的表层算子的逆来标定多次波,最后从原始记录中将多次波消除。整个预测过程无须知道宏观速度场,增强了预测方法的适应性。为更好地消除表层多次波,应采用迭代反演的方法。理论模型试算和实际资料试处理的结果表明,该方法对表层多次波有较好的压制作用,一般只需2～3次迭代即可。其处理效果要优于拉冬变换法,对100炮左右的常规数据来说,一次迭代一般需要30min左右。     

渗碳钢等温淬火多次冲击抗力的试验研究

本文试验研究证明:三种渗碳钢在渗碳一次再加热等温淬火处理后比通常渗碳一次再加热淬火回火处理具有更高的多次冲击弯曲抗力。当等温温度较低时,多次冲击侧向压缩抗力也较高。这就为进一步提高渗碳钢强度特性提供了一种新的强化工艺措施。试验分析指出:多次冲击抗力的这些变化规律是与载荷性质,金相组织(马氏体组织形态,马氏体与贝氏体相对量)及残余应力沿渗碳层分布密切相关的。     

基于布尔向量运算的Apriori算法

关联规则挖掘是数据挖掘中的一个重要课题,常用的Apriori 算法要多次扫描数据库,会产生大量的候选项集.利用向量的内积运算和逻辑运算提出了一种关联规则挖掘的改进算法.研究表明,该算法运算简单,只需要扫描一次数据库,不需要产生候选项集,且具有处理大型数据库的优点.     

红曲霉M1发酵糙米代谢产物抗S180细胞增殖效应研究

以红曲霉M1分别发酵大米和糙米,比较其代谢产物的变化;采用MTT比色法,初步研究了Monacolin K标准品、红曲糙米及红曲大米乙醇提取物对S180小鼠腹水瘤细胞的抑制作用. 结果表明：在MBR乙醇提取物中,可检测到MK的酸式构型,MK含量约为MR乙醇提取物的13倍. 经红曲霉M1发酵后,MBR中γ-氨基丁酸-GABA-质量浓度达到298mg/g,是MR乙醇提取物的31倍. MBR中桔霉素质量浓度低于MR. MK标准品、MBR及MR乙醇提取物均对S180小鼠腹水瘤细胞具有一定的抑制作用. MK质量浓度在3~50 μg/mL,三者抑制S180小鼠腹水瘤细胞增殖效应随MK质量浓度的增大而增大. 在MK含量相同的条件下,MR和MBR乙醇提取物的抑制效果显著大于MK标准品-P<001- .     

多次弹塑性撞击实验系统的设计与数值仿真

为了实验测量柔性撞击过程中的次撞击行为及其动力学响应,该文设计了一套多次弹塑性撞击实验系统.对该实验系统进行的三维动力有限元数值仿真结果表明,该系统可以激发出多次弹塑性撞击,有效地模拟几种典型构件之间的次撞击行为.采用数值仿真方法研究了测试梁材料、支承方式等对次撞击过程的影响,确定了满足实验要求的撞击力和梁位移测试性能指标.     

Android平台中无线定位的多次逆推模型

目的研究适用于资源受限的条件下的无线定位技术,建立基于Android终端的无线定位多次逆推模型,使系统具有较高的定位精度和较强的通用性.方法采用多次逆推模型进行多次定位,用终端的位移和方位角推导测试点位置坐标,综合多次定位结果推算测试点的位置坐标.结果在真实手机平台上实现了多次逆推模型,测试结果表明逆推次数为3~20次时,比常规一次定位精度提高20%~40%,验证了方案的可行性.结论采用多次逆推模型能够有效提高移动终端定位精度,同时没有增加移动终端的计算代价与资源消耗.     

层状介质模型的散射波场

运用逆散射序列方法能去除自由表面和内部多次波.通过研究正散射序列的性质,讨论了散射序列与一次波和多次波的关系,指出了用散射理论描述多次波和一次波的步骤和方法;此外,讨论了Bom近似与逆散射序列成像之间的差异.研究结果表明Bom近似成像法仅对于小扰动量适用,对于大扰动量,Bom近似值会产生较大的误差,而运用逆散射序列成像可以得到模型参数的精确值.     

超声激活血卟啉对在体艾氏腹水瘤杀伤效应的研究初报

利用超声激活血卟啉，研究对在体艾氏腹水瘤癌细胞的杀伤作用．实验分别选择不同的超声时间及取材时间．结果表明，单纯超声及血卟啉加超声组对肿瘤细胞均有杀伤作用．强度为0．9W／cm^2，声照3min，6h取材，为艾氏腹水瘤的杀伤效应最佳参数．     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

Design and analysis of generic LBS application developing platform

Location based services is promising due to its novel working style and contents.A software platform is proposed to provide application programs of typical location based services and support new applications developing efficiently. The analysis shows that this scheme is easy implemented, low cost and adapt to all kinds of mobile nework system.     

橡胶颗粒沥青混合料低温抗裂性试验研究

以AC-13级配为基础,将橡胶颗粒代替部分集料掺入混合料中,以低温弯曲试验为评价方法对不同橡胶颗粒掺量下沥青混合料的低温抗裂性进行研究,并引入应变能密度值对混合料的低温抗裂性进行综合评价.试验结果表明:橡胶颗粒沥青混合料试件的破坏微应变均超过2 300,满足冬寒区的技术指标;无论是否掺加橡胶颗粒,随着温度的下降,沥青混合料破坏时的最大弯拉强度增大,弯拉应变降低,劲度模量增大;弯曲应变能密度在胶粒掺量为1%左右时具有较大的弯曲应变能密度值,此时橡胶颗粒沥青混合料具有较好的低温抗裂性.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

Quantitative trait loci （QTLs） for quality traits related to protein and starch in wheat

Quality traits in wheat （Triticum aestirum L.） were studied by quantitative trait locus （QTL） analysis in a recombinant inbred line （RIL） population, a set of 131 lines derived from Chuan 35050 × Shannong 483 cross （ChSh）. Grains from RILs were assayed for 21 quality traits related to protein and starch. A total of 35 putative QTLs for 19 traits with a single QTL explaining 7.99-40.52% of phenotypic variations were detected on 10 chromosomes, 1D, 2A, 2D, 3B, 3D, 5A, 6A, 6B, 6D, and 7B. The additive effects of 30 QTLs were positive, contributed by Chuan 35050, the remaining 5 QTLs were negative with the additive effect contributed by Shannong 483. For protein traits, 15 QTLs were obtained and most of them were located on chromosomes 1 D, 3B and 6D, while 20 QTLs for starch traits were detected and most of them were located on chromosomes 3D, 6B and 7B. Only 7 QTLs for protein and starch traits were co-located in three regions on chromosomes 1D, 2A and 2D. These protein and starch trait QTLs showed a distinct distribution pattern in certain regions and chromosomes. Twenty-two QTLs were clustered in 6 regions of 5 chromosomes. Two QTL clusters for protein traits were located on chromosomes 1D and 3B, respectively, three clusters for starch traits on chromosomes 3D, 6B and 7B, and one cluster including protein and starch traits on chromosome 1D.     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.