评价孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床疗效及安全性

对孟鲁司特钠在小儿咳嗽变异性哮喘临床治疗中的疗效及安全性作出分析和评估。选择2015年3月-2018年12月于天水市甘谷县人民医院接受治疗的咳嗽变异性哮喘患儿74例为对象,将其分为孟鲁司特钠组与普通组,各37例。普通组应用布地奈德常规治疗,孟鲁司特钠组在普通组基础上加用孟鲁司特钠治疗。对两组肺功能指标、哮喘持续时间、哮鸣音消失时间、咳嗽消失时间、临床疗效、不良反应及复发情况进行比较。治疗后,孟鲁司特钠组肺功能指标水平优于普通组;孟鲁司特钠组哮喘持续时间、哮鸣音及咳嗽消失时间均短于普通组;此外,孟鲁司特钠组临床总有效率(94.59%)高于普通组(78.38%);且疾病复发率(5.41%)低于普通组(21.62%)(P0.05);此外,孟鲁司特钠组不良反应发生率(8.11%)低于普通组(16.22%),但对比差异不具备统计学意义(P0.05)。在小儿咳嗽变异性哮喘中应用孟鲁斯特进行治疗可明显提升治疗效果,改善患儿肺功能及临床症状,降低复发率,有助于促进患儿身体康复。     

孟鲁司特钠联合布地奈德雾化吸入对咳嗽变异性哮喘患儿疗效及肺功能的影响

目的:观察孟鲁司特钠联合布地奈德雾化吸入对咳嗽变异性哮喘(CVA)患儿疗效及肺功能的影响.方法:选取玉门市第一人民医院确诊为CVA患儿80例作为研究对象,将其按照随机数字表法分为试验组和对照组各40例,对照组采用布地奈德雾化吸入治疗,试验组在对照组基础上联合孟鲁司特钠治疗,观察两组患儿临床治疗效果、肺功能以及不良反应发生率.结果:试验组总有效率95.00％高于对照组75.00％(p＜ 0.05);治疗后两组患儿FEV1、PEF、FVC均较治疗前升高(p＜0.05),且试验组显著优于对照组(p＜0.05);试验组不良反应发生率5.00％低于对照组17.50％(p＜ 0.05).结论:采用孟鲁司特钠联合布地奈德雾化吸入治疗CVA患儿可有效提高治疗效果,改善肺功能.     

孟鲁司特钠联合布地奈德用于小儿咳嗽变异性哮喘的有效性分析

观察孟鲁司特钠与布地奈德联合应用于小儿咳嗽变异性哮喘临床治疗中所产生的效果。选取肃北蒙古族自治县人民医院收治的92例咳嗽变异性哮喘患儿,依据随机数字表法随机分为对照组和研究组,每组46例,其中对照组患儿接受布地奈德治疗,研究组患儿接受孟鲁司特钠与布地奈德联合治疗,3个月后评价2组疗效,并检测2组患儿肺功能相关指标。研究组总有效率92.86%与对照组69.05%比较,差异有统计学意义(P0.05);治疗后2组肺功能指标明显上升(P0.05),且研究组肺功能指标均明显优于对照组(P0.05)。联合孟鲁司特钠与布地奈德治疗小儿咳嗽变异性哮喘疗效突出,同时还具有明显改善患儿肺功能的优势。     

孟鲁司特钠与沙美特罗/氟替卡松联合治疗咳嗽变异性哮喘的临床分析

分析孟鲁司特钠与沙美特罗/氟替卡松联合治疗咳嗽变异性哮喘的临床效果。选取我院收治的咳嗽变异性哮喘94例,随机将其分为对照组和联合组,各47例。对照组采用沙美特罗/氟替卡松治疗,联合组在对照组基础上联合孟鲁司特钠治疗,比较两组的临床疗效。治疗前,两组FEV1和PEF等肺功能指标比较无统计学差异(P0.05),两组治疗后肺功能指标均改善,且联合组的改善效果优于对照组,差异有统计学意义(P0.05);联合组临床有效率95.74%,高于对照组的80.85%,差异有统计学意义(P0.05)。孟鲁司特钠与沙美特罗/氟替卡松联合治疗咳嗽变异性哮喘的临床效果显著,可明显改善机体肺功能指标,且临床有效率高,值得临床普遍应用。     

舒利迭与孟鲁司特钠联合治疗对支气管哮喘患者肺功能的影响

观察舒利迭与孟鲁司特钠联合用药对支气管哮喘患者肺功能的影响。选取甘肃省定西市中医院收治的支气管哮喘患者92例作为研究对象,随机分为对照组和研究组,各46例。两组患者入院后均进行抗感染、平喘、止咳等常规基础治疗,对照组在常规治疗基础上给予舒利迭进行治疗,研究组在对照组基础上加用孟鲁司特钠进行治疗,两组均连续治疗3个月。观察两组患者治疗前后肺功能变化情况以及临床治疗效果。两组患者治疗前FEV1、FEV1/FVC水平差异无统计学意义(P0.05),治疗后较治疗前均有所上升(P0.05),且治疗后研究组FEV1、FEV1/FVC水平均明显高于对照组(P0.05);研究组临床治疗总有效率95.65%明显高于对照组80.43%(P0.05)。舒利迭与孟鲁司特钠联合治疗支气管哮喘疗效显著,且能明显改善患者肺功能,值得临床应用推广。     

孟鲁司特钠对慢性阻塞性肺疾病急性加重期患者炎症因子及肺功能的影响

目的:观察孟鲁司特钠对COPD急性加重期患者炎症因子及肺功能影响.方法:选取2016年1月~12月在我院治疗COPD急性加重期患者84例作为研究对象,运用随机数字法将其分为观察组(42例)与对照组(42例).对照组临床常规对症治疗,观察组则在对照组用药治疗基础上加以孟鲁司特钠治疗.观察两组治疗前后炎症因子、肺功能与临床疗效.结果:观察组总有效率高于对照组,差异有统计学意义(p<0.05);治疗前两组PCT、CRP、FEV1、FEV1/FVC以及FEV1%Pred水平对比,差异无统计学意义(p>0.05);治疗后观察组PCT、CRP、FEV1、FEV1%Pred、FEV1/FVC测定结果均优于对照组,差异有统计学意义(p<0.05).结论:孟鲁司特钠有助于COPD急性加重期患者肺功能改善,降低机体内炎症因子水平,进而延缓病症进展,临床普及价值高.     

孟鲁司特钠与酮替芬联合治疗小儿支气管炎的疗效分析

分析孟鲁司特钠与酮替芬联合治疗小儿支气管炎的临床疗效。选取2015年1月-2016年5月我院收治的小儿支气管炎患者118例,随机分为观察组和对照组,对照组患者给予孟鲁斯特纳治疗,观察组患者给予孟鲁司特钠联合酮替芬治疗,观察两组患者治疗效果、临床症状消失时间及不良反应。观察组患者治疗有效率96.61%明显高于对照组74.58%(P0.05);观察组患者体温恢复时间、咳嗽消失时间、肺部喘鸣音消失时间及干湿啰音消失时间均明显短于对照组且组间差异有统计学意义(P0.05);观察组患者不良反应发生率6.78%显著低于对照组18.64(P0.05)。孟鲁司特钠联合酮替芬治疗小儿支气管炎可显著提高治疗效果,缩短病程,降低不良反应发生率。     

布地奈德联合孟鲁司特对哮喘患者肺功能及免疫功能的影响分析

目的探讨布地奈德联合孟鲁司特对哮喘患者进行干预后患者肺功能及免疫功能的变化.方法将80例哮喘患者分为观察组和对照组,对照组采用布地奈德雾化吸入,观察组在对照组基础上服用孟鲁司特片;在治疗前及治疗结束2周后观察患者肺功能、血清IL-4及INF-γ、外周血Ig E和嗜酸性粒细胞(EOS)水平.结果治疗后两组患者FEV1,FEV1/FVC及PEF均显著升高(P0.05),且观察组升高水平显著高于对照组(P0.05);治疗后患者血清中IL-4水平显著降低(P0.05),INF-γ显著升高(P0.05),且观察组患者IL-4降低水平及INF-γ升高水平均显著高于对照组(P0.05);治疗后两组患者外周血Ig E及EOS水平均显著降低(P0.05),且观察组患者降低水平显著高于对照组(P0.05).结论应用布地奈德联合孟鲁司特对哮喘患者进行治疗,可有效改善患者肺功能及免疫功能,提高临床疗效.     

舒利迭单用及联合孟鲁司特治疗哮喘临床对照研究

探究舒利迭单用及联合孟鲁司特治疗哮喘临床疗效。选取天祝县人民医院收治的128例哮喘患者作为研究对象,对其进行随机分组,根据治疗方法不同,分为对照组和观察组,每组64例。对照组单用舒利迭治疗,观察组在对照组的基础之上联合孟鲁司特进行治疗。观察两组患者在治疗后哮喘改善情况。观察组总有效率为98.44%显著高于对照组82.81%(P0.05),两组患者临床治疗期间不良反应比较差异无统计学意义(P0.05)。哮喘患者采用舒利迭联合孟鲁司特治疗疗效更为明显,且不良反应发生率低。     

中西医结合治疗51例儿童过敏性紫癜疗效观察

观察中西医结合治疗儿童过敏性紫癜的临床疗效。方法将符合纳入标准的102例过敏性紫癜患儿,随机分为2组。对照组51例给予常规的西医治疗,观察组51例在常规西医治疗的基础上加用中药内服,两组患儿均连续治疗7天。观察两组临床疗效及复发率。观察组总有效率为98.03℅,对照组为83.70℅,两组相比差异有统计学意义(P﹤0.05);观察组复发率为3.8℅(2∕52),对照组复发率为17.30℅(9∕52),两组复发率比较差异有统计学意义(P﹤0.05)。在儿童过敏性紫癜的治疗中,中西医联合治疗可提高疗效,减少复发率,值得临床推广应用     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

Design and analysis of generic LBS application developing platform

Location based services is promising due to its novel working style and contents.A software platform is proposed to provide application programs of typical location based services and support new applications developing efficiently. The analysis shows that this scheme is easy implemented, low cost and adapt to all kinds of mobile nework system.     

橡胶颗粒沥青混合料低温抗裂性试验研究

以AC-13级配为基础,将橡胶颗粒代替部分集料掺入混合料中,以低温弯曲试验为评价方法对不同橡胶颗粒掺量下沥青混合料的低温抗裂性进行研究,并引入应变能密度值对混合料的低温抗裂性进行综合评价.试验结果表明:橡胶颗粒沥青混合料试件的破坏微应变均超过2 300,满足冬寒区的技术指标;无论是否掺加橡胶颗粒,随着温度的下降,沥青混合料破坏时的最大弯拉强度增大,弯拉应变降低,劲度模量增大;弯曲应变能密度在胶粒掺量为1%左右时具有较大的弯曲应变能密度值,此时橡胶颗粒沥青混合料具有较好的低温抗裂性.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

Quantitative trait loci （QTLs） for quality traits related to protein and starch in wheat

Quality traits in wheat （Triticum aestirum L.） were studied by quantitative trait locus （QTL） analysis in a recombinant inbred line （RIL） population, a set of 131 lines derived from Chuan 35050 × Shannong 483 cross （ChSh）. Grains from RILs were assayed for 21 quality traits related to protein and starch. A total of 35 putative QTLs for 19 traits with a single QTL explaining 7.99-40.52% of phenotypic variations were detected on 10 chromosomes, 1D, 2A, 2D, 3B, 3D, 5A, 6A, 6B, 6D, and 7B. The additive effects of 30 QTLs were positive, contributed by Chuan 35050, the remaining 5 QTLs were negative with the additive effect contributed by Shannong 483. For protein traits, 15 QTLs were obtained and most of them were located on chromosomes 1 D, 3B and 6D, while 20 QTLs for starch traits were detected and most of them were located on chromosomes 3D, 6B and 7B. Only 7 QTLs for protein and starch traits were co-located in three regions on chromosomes 1D, 2A and 2D. These protein and starch trait QTLs showed a distinct distribution pattern in certain regions and chromosomes. Twenty-two QTLs were clustered in 6 regions of 5 chromosomes. Two QTL clusters for protein traits were located on chromosomes 1D and 3B, respectively, three clusters for starch traits on chromosomes 3D, 6B and 7B, and one cluster including protein and starch traits on chromosome 1D.     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.