| 基于BB—SIR方法的结肠癌特征基因提取 |
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| 引用本文： | 李杰,邓丽君,唐胜男.基于BB—SIR方法的结肠癌特征基因提取[J].世界科技研究与发展,2011,33(4):588-591. |
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| 作者姓名： | 李杰 邓丽君 唐胜男 |
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| 作者单位： | 云南大学数学与统计学院统计系,昆明,650091 |
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| 基金项目： | 云南大学第三届研究生科研立项基金（ynuy201036）
致谢感谢唐年胜教授在论文撰写中提出的宝贵意见,也同时感谢邓丽君和唐胜男对本文所做的工作. |
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| 摘 要： | 结合复杂数据分析（Complex Data Analysis）理论和充分降维的思想，在有效提取结肠癌特征基因研究的基础上，建立结肠癌特征基因提取的BB-SIR模型。该模型方法简洁易懂且有较高的识别率。依据BB-SIR模型和所给数据找到了两个结肠癌亚型，并确定了该亚型的特征基因。实验结果表明，BB—SIR方法选出的特征基因能够识别出结肠癌亚型，并且识别正确率达到96％以上。
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| 关 键 词： | 特征基因 结肠癌 BB—SIR |
Refinement Procedure for Eigen Genes of Colon Carcinoma Based on BB-SIR |
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| LI Jie,DENG Lijun,TANG Shengnan.Refinement Procedure for Eigen Genes of Colon Carcinoma Based on BB-SIR[J].World Sci-tech R & D,2011,33(4):588-591. |
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| Authors: | LI Jie DENG Lijun TANG Shengnan |
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| Institution: | (Statistics department of mathematics and statistics school, Yunnan University Kunming 650091 ) |
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| Abstract: | A new model of refining eigen genes of colon carcinoma, Bhattacharyya-Bootstrap-SIR, was established based on the study of sufficient refinement of eigen genes of colon carcinoma, combined theory of complex data analysis and sufficient dimension reduction. The model, called BB-SIR in brief,is easy to understand and has high rate of recognization. Two sub-colon carcinomas is founded by using the BB-SIR model and the sample data, futhermore we determined the eigen genes of two sub-colon carcinomas. The result showed that BB-SIR model can find the eigen genes of colon carcinma and can specify the two sub-colon carcinomas, the correct rate of recognization is at least as high as 96%. |
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| Keywords: | eigen genes colon carcinoma BB-SIR |
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