| 2-苯氧甲基-5-芳基-1,3,4-噁二唑化合物的合成与结构表征 |
| |
| 引用本文： | 李德江,葛正红.2-苯氧甲基-5-芳基-1,3,4-噁二唑化合物的合成与结构表征[J].西南师范大学学报(自然科学版),2005,30(2):293-296. |
| |
| 作者姓名： | 李德江 葛正红 |
| |
| 作者单位： | 1. 郧阳师范高等专科学校,化学系,湖北,丹江口市,442700
2. 江苏工业学院,化工系,江苏,常州,213016 |
| |
| 基金项目： | 湖北省教育厅2004年科学技术研究项目(2004D001). |
| |
| 摘 要： | 以苯氧乙酸乙酯与水合肼反应制得苯氧乙酰肼, 该化合物在以碳酸钠作缚酸剂, 分别与苯甲酰氯、3,4,5 三甲氧基苯甲酰氯、4 硝基苯甲酰氯、4 甲氧基苯甲酰氯、呋喃甲酰氯、3,5 二甲基苯甲酰氯, 4 氯苯甲酰氯反应得到相应的N, N/ 二酰基肼, 然后在POCl3 作用下, 脱水环化成2 苯氧甲基5 芳基1,3,4 噁二唑化合物. 通过元素分析, IR, 1H NMR和MS对其结构进行表征, 并对其裂解途径进行了探讨.
|
| 关 键 词： | 1 3 4-噁二唑 合成 结构表征 |
| 文章编号： | 1000-5471(2005)02-0293-04 |
| 修稿时间： | 2004年5月25日 |
Synthesis and Structural Characterization of 2-Phenoxymethyl-5-Aryl-1,3,4-Oxadiazoles |
| |
| LI De-jiang,GE Zheng-hong.Synthesis and Structural Characterization of 2-Phenoxymethyl-5-Aryl-1,3,4-Oxadiazoles[J].Journal of Southwest China Normal University(Natural Science),2005,30(2):293-296. |
| |
| Authors: | LI De-jiang GE Zheng-hong |
| |
| Abstract: | Phenoxyacetyl hydrazine was synthesized by reaction of ethyl phenoxyacetate with hydrazine hydrate. This compound respectively reacted with benzoyl chloride, 3,4,5-trimethoxymethyl benzoyl chloride, 4-nitrobenzoyl chloride, 4-methoxybenzoyl chloride, furoryl chloride, 3,5-dimethyibenzoyl chloride, and 4-chlorobenzoyl chloride in the presence of Na 2CO 3 as acid acceptor for 34 h to give corresponding N, N/-diacylhydrazines. Then intermediates cyclized with POCl 3 to afford seven novel 2-phenoxy-5-aryl-1,3,4-oxadiazoles. Their structures were characterized by elementary analyses, IR, (~1H) NMR, and MS spectroscopy, and fragmentation mechanism of MS spectra was discussed as well. |
| |
| Keywords: | oxadiazoles synthesis structural characterization |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《西南师范大学学报(自然科学版)》浏览原始摘要信息 |
| 点击此处可从《西南师范大学学报(自然科学版)》下载免费的PDF全文 |
|
