| 微波辐射催化合成乙酰水杨酸 |
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| 引用本文： | 李西安,李丕高,贺宝宝,李苗.微波辐射催化合成乙酰水杨酸[J].延安大学学报(自然科学版),2005,24(3):49-50,85. |
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| 作者姓名： | 李西安 李丕高 贺宝宝 李苗 |
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| 作者单位： | 延安大学,化学与化工学院,陕西,延安,716000 |
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| 摘 要： | 在微波辐射下以碳酸氢钠为催化剂合成乙酰水杨酸,考察了影响反应的主要因素,实验结果表明合成最佳工艺条件为n(水杨酸)∶n(乙酸酐)=1∶2.0,微波功率为微波炉“中低”档(40%)151W,辐射时间45 s,催化剂用量为水杨酸质量的2%,产率可达96.9%(重结晶产率可达92.1%)。
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| 关 键 词： | 微波辐射 水杨酸 乙酸酐 乙酰水杨酸 合成 |
| 文章编号： | 1004-602X（2005）03-0049-02 |
| 收稿时间： | 2004-11-20 |
| 修稿时间： | 2004-11-20 |
Synthesis of acetylsalicylic acid by microwave irradiation under the assistance of sodium bicarbonate catalyst |
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| LI Xian,LI Pi-gao,HE Bao-bao,LI Miao.Synthesis of acetylsalicylic acid by microwave irradiation under the assistance of sodium bicarbonate catalyst[J].Journal of Yan'an University(Natural Science Edition),2005,24(3):49-50,85. |
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| Authors: | LI Xian LI Pi-gao HE Bao-bao LI Miao |
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| Institution: | College of Chemistry and Chemical Engineering, Yanan University, Yanan 716000,China |
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| Abstract: | Aspirin was synthesized by microwave radiation, using salicylic acid and acetic anhydride as raw materials and anhydrous sodium bicarbonate as a catalyst. The optimal condition aspirin was synthesized by molar ratio of salicylic acid to acetic acid anhydride was 1:2.0, the time of radiation was 45s, the weight of anhydrous sodium bicarbonate was 2% of salicylic acid ,The yield was over 92.1%. The method was of characteristic of easy operation control and high yield. |
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| Keywords: | microwave radiation salicylic acid acetic acid anhydride acetylsalicylic acid synthesis |
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