| 纳米碳羟基磷灰石的制备及载药性能研究 |
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| 引用本文： | 唐松,曾荣英,李春莉,刘洪水,王尹鹏.纳米碳羟基磷灰石的制备及载药性能研究[J].衡阳师专学报,2010(6):169-171. |
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| 作者姓名： | 唐松 曾荣英 李春莉 刘洪水 王尹鹏 |
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| 作者单位： | 衡阳师范学院化学与材料科学系,湖南衡阳421008 |
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| 基金项目： | 衡阳师范学院2009年大学生研究性学习和创新实验计划项目资助 |
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| 摘 要： | 利用废弃蛋壳为原材料,水热法合成碳羟基磷灰石（CHAP）,通过X射线衍射、扫描电镜、能谱分析手段对其结构进行了表征,将CHAP作为维C的载体,研究其载药效果。结果表明：在pH为6、温度为40℃、负载时间1h,纳米微粒CHAP对初始浓度的50 mg/L维C负载量高达33.08 mg/g。因此,纳米CHAP作为载药载体有着巨大的开发潜力。
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| 关 键 词： | 纳米碳羟基磷灰石 制备 载药 |
The Preparation of Nano Carbonate Hydroxyapatite and Loaded Drug Characterization |
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| TANG Song,ZENG Rong-ying,LI Chun-li,LIU Hong-shui,WANG Yin-peng.The Preparation of Nano Carbonate Hydroxyapatite and Loaded Drug Characterization[J].Journal of Hengyang Normal University,2010(6):169-171. |
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| Authors: | TANG Song ZENG Rong-ying LI Chun-li LIU Hong-shui WANG Yin-peng |
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| Institution: | (Department of Chemistry and Materials Science,Hengyang Normal University,Hengyang Hunan 421008,China) |
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| Abstract: | The characterization of drug-loaded Vitamin C by home-made carbonate hydroxylapatite（CHAP） synthesized by using abandoned eggshell was characterized by transmit selectron microscopy（TEM）,X-ray diffraction（XRD） and energy depressive spectroscopy（EDS）.The result showed that the loading capacity for Vitamin C by CHAP nanoparticles could reach 33.08 mg/mg,when the initial Vitamin C concentration was 50 mg/L and pH was 3.0 and the loaded period was 1h at 40 ℃.Therefore,the CHAP nanoparticles have potential applications as a drug-loading carrier. |
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| Keywords: | Nana carbonate hydroxyaptite synthesis drug-loaded |
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