二苯甲酮酰胺衍生物的合成与表征

以邻苯二甲酸酐和不同的取代苯为原料,经过傅克反应得到邻芳酰基苯甲酸,再与不同的胺类化合物合成一系列二苯甲酮酰胺衍生物,总反应收率为71.2%～91.7%.通过在二苯甲酮上引入酰胺羧酸类活性基团,不仅其可以作为光化学前体用于提高光反应的立体选择性,而且还可直接应用于其他化学领域.其结构已经核磁和质谱表征.

Synthesis and Characterization of benzophenone acylamide derivatives

2-benzoyl- Benzoic acid was prepared from phthalic anhydride and different substituted benzene through Friedel-Crafts reaction, which reacted with various amine compounds to afford Benzophenone acylamide derivatives in total yields of 71.2~91.7% .The induction of acylamide group can enhance the stereoselectivity of photochemistry and be used in other chemistry fields. The structures were characterized by 1H NMR and MS.