| 槭叶草总黄酮对大鼠心力衰竭治疗作用的机制研究 |
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| 引用本文： | 曲娴,刘建平.槭叶草总黄酮对大鼠心力衰竭治疗作用的机制研究[J].北华大学学报(自然科学版),2000,1(3):216-217. |
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| 作者姓名： | 曲娴 刘建平 |
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| 作者单位： | [1]北华大学医学院 [2]第四军医大学吉林军医学院 |
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| 基金项目： | 吉林省教委资助项目!(吉教合字 9733) |
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| 摘 要： | 研究叶草总黄酮（ＴＦＭ）对心衰鼠治疗作用机制。方法 实验采用狭窄腹主动脉法造成大鼠充血性心力衰竭模型。结果 表明ＴＦＭ能明显保护超氧化物岐化酶（ＳＯＤ）的活性，降低丙二醛（ＭＤＡ）的质量浓度，提高心钠素（ＡＮＰ）的质量浓度。结论 揭示ＴＦＭ对心衰鼠治疗作用机制与降低血中ＭＤＡ质量浓度和升高ＳＯＤ活性及ＡＮＰ质量浓度有关。
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| 关 键 词： | 槭叶草总黄酮 心力衰竭 心钠素 TFM SOD 治疗 |
Experimental Study on the Mechanism of TFM for the Treatment on Rats with Heart Failure |
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| Qu Xian ,Liu Jianping ,Jiang Liping ,Yang Zongwan.Experimental Study on the Mechanism of TFM for the Treatment on Rats with Heart Failure[J].Journal of Beihua University(Natural Science),2000,1(3):216-217. |
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| Authors: | Qu Xian Liu Jianping Jiang Liping Yang Zongwan |
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| Institution: | Qu Xian 1,Liu Jianping 2,Jiang Liping 2,Yang Zongwan 2 |
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| Abstract: | Objective The animal models of heart failure are made by using the method of stenosic abdominal aorta of rat. Methods To observe the therapeutic effects of TFM on rat with heart failure. Results TFM protected activity of SOD, increaed ANP content and reduced MDA content significantly.Conclusion It is believed that the mechanism of therapeutic effect of TFM on rat with heart failure was closely related to increase SOD activity, ANP content and decrease MDA content in blood. |
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| Keywords: | TFM Heart failure SOD MDA ANP |
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