猕猴结肠镜检查前的肠道准备

摘要:猕猴是非常重要且珍贵的实验动物。 不处死猕猴为前提,以反复多次对猕猴进行全结肠肠道检查及研究为。目的,建立猕猴全结肠内镜检查前的肠道准备方法尤为重要。 本研究补充此方法目前尚无报道的空白。 30 只猕猴,结肠镜检查前 3 h 分多次予以芒硝溶液管喂。 通过肠镜观察肠道清洁情况,其中 3 只猕猴肠道准备为Ⅲ 级,其余猕猴肠道准备均为Ⅰ ~ Ⅱ 级。 所有猕猴在洗肠过程中,无严重脱水、休克、死亡等并发症发生,肠道准备为Ⅰ ~ Ⅱ级猕猴顺利完成全结肠内镜检查。

Bowel Preparation before Colonoscopy on Macaques

Abstract:Macaques are very important and precious laboratory animals. The aim of this study was to examine theentire colon on alive macaques repeatedly. In order that,it is particularly important to establish a method about colon preparation before colonoscopy. But until now there are no reports on specific preparation method for colonoscopy on macaques. The aim of this study was to develop a method of bowel preparation before colonoscopy on macaques. Thirty macaques were fed with glauber’ s salt through nasogastric tubes several times before colonoscopy. Intestinal cleansing was observed by colonoscopy. Three macaques were prepared for grade Ⅲ and the rest of the macaques were grade Ⅰ and grade Ⅱ . All macaques did not have serious complications such as dehydration, shock, and death during the process of washing the intestines. The colonoscopy was successfully completed on intestinal preparations of grade Ⅰ and grade Ⅱ macaques.