| 毒扁豆碱的合成研究进展 |
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| 引用本文： | 周永云,孙蔚青,韩柏秋,杨大坚,杨勇,樊保敏.毒扁豆碱的合成研究进展[J].云南民族大学学报(自然科学版),2015(3):165-175. |
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| 作者姓名： | 周永云 孙蔚青 韩柏秋 杨大坚 杨勇 樊保敏 |
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| 作者单位： | 云南民族大学民族药资源化学国家民委-教育部重点实验室;重庆市中药研究院 |
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| 基金项目： | 国家自然科学基金(21302162;21362043) |
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| 摘 要： | 介绍了具有六氢吡咯吲哚环系结构单元的毒扁豆碱结构、生物活性及其合成研究进展.主要从不同的方法对C3a位季碳的构筑,从而对合成毒扁豆碱天然产物的合成方法进行归纳和总结.
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| 关 键 词： | 毒扁豆碱 生物碱 合成 串联反应 催化 |
Review of the synthesis of physostigmine |
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| ZHOU Yong-yun;SUN Wei-qing;HAN Bai-qiu;YANG Da-jian;YANG Yong;FAN Bao-min.Review of the synthesis of physostigmine[J].Journal of Yunnan Nationalities University:Natural Sciences Edition,2015(3):165-175. |
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| Authors: | ZHOU Yong-yun;SUN Wei-qing;HAN Bai-qiu;YANG Da-jian;YANG Yong;FAN Bao-min |
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| Institution: | ZHOU Yong-yun;SUN Wei-qing;HAN Bai-qiu;YANG Da-jian;YANG Yong;FAN Bao-min;Key Laboratory of Chemistry in Ethnic Medicinal Resources,State Ethnic Affairs Commission and Ministry of Education of China,Yunnan Minzu University;Chongqing Academy of Chinese Materia Medica; |
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| Abstract: | The researches on the structures,synthesis and bioactivity of physostigmine with a hexahydropyrroloindole unit are reviewed. With a consideration of different approaches to the C3 aconstruction of quaternary carbon,the synthetic methods of physostigmine are summarized. |
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| Keywords: | physostigmine alkaloid synthesis sequential reaction catalyze |
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