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Synthesis of novel tailed porphyrins with covalently linked saccharide
Authors:Li Zao-ying  Wang Kai  Zhu Xun-jin  Zhu Yi
Institution:(1) College of Chemistry and molecular sciences, Wuhan University, 430072 Wuhan Hubei, China;(2) Institute of Red Heart King Co. Ltd., 430070 Wuhan Hubei, China
Abstract:The reaction of 5-(p-hydroxyphenyl)-10,15,20-(p-methoxy phenyl) porphyrin with Br(CH2)4Br produced monobromo substituted porphyrin 1. The tailed porphyrins 2-4 were synthesized by the reactions of 1 with small molecular offering biological activities such as D-glucose, D-glucuronic acid. These new compounds were confirmed by 1H NMR, IR, UV-vis and element analyses.
Keywords:carbohydrate substituted porphyrins  synthesis  characterization
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