| 人参汤提取物对血管内皮细胞保护作用的研究 |
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| 引用本文： | 白秀云,王伟明,张树明,白海玉.人参汤提取物对血管内皮细胞保护作用的研究[J].哈尔滨商业大学学报(自然科学版),2006,22(3):11-13. |
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| 作者姓名： | 白秀云 王伟明 张树明 白海玉 |
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| 作者单位： | 1. 黑龙江省中医研究院,黑龙江,哈尔滨,150036
2. 黑龙江中医药大学,黑龙江,哈尔滨,150060 |
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| 摘 要： | 探讨人参汤提取物对血管内皮细胞的保护作用.采用体内、外血管内皮细胞损伤模型,测定体外血管内皮细胞破裂MTT染色后的OD值、体内血管内皮细胞损伤时血中CEC数及血清中NO的浓度.体外实验人参汤各剂量组的OD值比模型对照组降低(P<0.05)、体内实验人参汤各剂量组CEC数量、NO浓度比模型对照组都显著降低(P<0.01).实验结果表明,人参汤提取物对血管内皮细胞的损伤具有保护作用.
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| 关 键 词： | 人参汤 血管内皮细胞 大鼠 CEC NO |
| 文章编号： | 1672-0946(2006)03-0011-03 |
| 修稿时间： | 2006年2月22日 |
Study on protective effect of extraction of ginseng decoction on vascular endothelial cell |
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| BAI Xiu-yun,WANG Wei-ming,ZHANG Shu-ming,BAI Hai-yu.Study on protective effect of extraction of ginseng decoction on vascular endothelial cell[J].Journal of Harbin University of Commerce :Natural Sciences Edition,2006,22(3):11-13. |
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| Authors: | BAI Xiu-yun WANG Wei-ming ZHANG Shu-ming BAI Hai-yu |
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| Abstract: | To investigate the protective effects of the extraction of ginseng decoction on vascular endothelial cells.Mensurating the MTT OD value of in vitro vascular endothelial cells,CEC of blood as in vivo vascular endothelial cells were injured,and NO concentration in blood serum using the injury model of in vitro and vivo vascular endothelial cells.It was found that ginseng decoction decreased significantly the MTT OD value(P<0.05 vs control group) for In vitro experiments,and decreased significantly the CEC and NO concentration in blood serum(P<0.01 vs control group) for in vivo experiments.The extraction of ginseng decoction exerts protective effects on injured vascular endothelial cells. |
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| Keywords: | ginseng decoction vascular endothelial cell rat CEC NO |
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