| 几种抗氧化剂对脂质过氧化的抑制作用 |
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| 引用本文： | 刘国安,王莱,杨庆明,叶佳,丁兰,杨红.几种抗氧化剂对脂质过氧化的抑制作用[J].西北师范大学学报,2005,41(5):52-53,58. |
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| 作者姓名： | 刘国安 王莱 杨庆明 叶佳 丁兰 杨红 |
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| 作者单位： | 西北师范大学生命科学学院,甘肃兰州730070 |
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| 基金项目： | 西北师范大学青年教师科研基金资助课题（NWNU-QN-2003-11） |
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| 摘 要： | 以大鼠肝微粒体为材料检测了几种常用抗氧化剂对由Fe^2＋／Vc启动的脂质过氧化的抑制作用．各化合物的抗氧化作用都呈浓度依赖关系．以半抑制浓度表示其抗氧化作用．结果表明，抗氧化作用由强到弱的次序为槲皮素〉BHT〉Trolox〉芦丁〉焦性没食子酸〉硫脲〉亚硒酸钠〉Vc〉甘露醇．
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| 关 键 词： | 抗氧化剂 脂质过氧化 微粒体 |
| 文章编号： | 1001-988X（2005）05-0052-02 |
| 收稿时间： | 2005-04-22 |
| 修稿时间： | 2005-04-222005-08-30 |
Inhibitions of lipid peroxidation by several antioxdants |
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| Liu GuoAn;Wang Lai;Yang QingMing;Xie Jia;Ding Lan;Yang Gong.Inhibitions of lipid peroxidation by several antioxdants[J].Journal of Northwest Normal University Natural Science (Bimonthly),2005,41(5):52-53,58. |
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| Authors: | Liu GuoAn;Wang Lai;Yang QingMing;Xie Jia;Ding Lan;Yang Gong |
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| Abstract: | Several normal antioxidants are studied for their activities as inhibitors of lipid peroxidation.The peroxidation is initiated by Vc/Fe~(2 ) in rat liver microsomes.It is found that all these compounds show concentration-dependant antioxidative effects.The inhibition of lipid peroxidation by these compounds is showed as the concentration values yielding 50% inhibition.The activity sequence is quercetin>BHT>trolox>rutin>pyrogallic acid>thiourea>sodium selenite>vitamin C>mannitol. |
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| Keywords: | antioxidant lipid peroxidation microsome |
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