| Progress in non-viral gene delivery systems fabricated via supramolecular assembly |
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| 作者姓名： | WANGYouxiang SHENJiacong |
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| 作者单位： | DepartmentofPolymerScienceandEngineering,ZhejiangUniversity,Hangzhou310027,China |
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| 摘 要： | Gene delivery systems are one of key issues that limit the development of gene therapy. The novel non-viral gene delivery systems fabricated via supramolecular assembly have begun to show increasing promising and applications in gene therapy due to its suitable nanometric size,controllable structure and excellent biocompatibility. In this review, the fundamental and recent progress of non-viral gene supramolecular assembly is reviewed. Artificial viruses the future direction of non-viral gene delivery systems are also described.
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| 关 键 词： | 基因治疗 人造病毒 超分子集合 基因技术 结构特征 DNA |
| 收稿时间： | 27 February 2004 |
Progress in non-viral gene delivery systems fabricated via supramolecular assembly |
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| WANGYouxiang SHENJiacong.Progress in non-viral gene delivery systems fabricated via supramolecular assembly[J].Chinese Science Bulletin,2005,50(4):289-294. |
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| Authors: | Youxiang Wang Jiacong Shen |
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| Institution: | (1) Department of Polymer Science and Engineering, Zhejiang University, 310027 Hangzhou, China |
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| Abstract: | Gene delivery systems are one of key issues that limit the development of gene therapy. The novel non-viral gene delivery
systems fabricated via supramolecular assembly have begun to show increasing promising and applications in gene therapy due
to its suitable nanometric size, controllable structure and excellent biocompatibility. In this review, the fundamental and
recent progress of non-viral gene supramolecular assembly is reviewed. Artificial viruses—the future direction of non-viral
gene delivery systems are also described. |
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| Keywords: | non-viral gene vectors gene therapy supramolecular assembly artificial virus |
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