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乳酸菌肽与模拟生物膜脂质体的相互作用
引用本文:李昕,周静,杨昌英.乳酸菌肽与模拟生物膜脂质体的相互作用[J].三峡大学学报(自然科学版),2009,31(6):89-93.
作者姓名:李昕  周静  杨昌英
作者单位:1. 三峡大学,化学与生命科学学院,湖北,宜昌,443002
2. 三峡旅游职业技术学院,湖北,宜昌,443100
摘    要:通过同步荧光法,循环伏安法和交流阻抗法,研究了乳酸菌肽与模拟生物膜脂质体的相互作用.实验研究发现这种肽和带正电的脂质体间存在相互作用,乳酸菌肽可以支撑双层内脂膜产生孔隙,它使得标记离子Fe(CN)6^3-/4-穿过内脂膜,在玻碳电极(GCE)上发生氧化还原反应,这种作用与时间和乳酸菌肽的浓度都有关.

关 键 词:乳酸菌肽  脂质体  同步荧光法  循环伏安法  交流阻抗法

Research on Interaction of Lactobacillus Peptide and Biofilm Liposome
Li Xin,Zhou Jing,Yang Changying.Research on Interaction of Lactobacillus Peptide and Biofilm Liposome[J].Journal of China Three Gorges University(Natural Sciences),2009,31(6):89-93.
Authors:Li Xin  Zhou Jing  Yang Changying
Institution:Li Xin Zhou Jing Yang Changying(1. College of Chemistry & Life Science, China Three Gorges Univ. , Yiehang 443002, China; 2. Three Gorges Tourism College, Yiehang 443100, China)
Abstract:The interaction of lactobacillus peptide and liposome was researched by using synchronous spectrofluorimetry,cyclic voltammetry and a.c.impedance.This kind of lactobacillus peptide interacted with electropositive liposome.It could produce pores in the supported bilayer lipid membrane,led the marker ions Fe(CN)6^3-/4-crossing the lipid membrane and take place redox reaction on the glassy carbon electrode(GCE).The role of them is related to time and the concentration of lactobacillus peptide.
Keywords:lactobacillus peptide  liposome  synchronous spectrofluorimetry  cyclic voltammetry  a  c  impedance
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