质谱双探针法对食品中N- 亚硝胺化合物的全检测

食品中亚硝胺化合物的种类达300种,当前的亚硝胺检测国标只检测代表性的4种亚硝胺化合物.选择亚硝胺类化合物在EI源质谱中电离出的亚硝酰胺基(N2O)和亚硝酰(NO)2个独特碎片离子作双探针信号,以市售腊肉为检测对象,探索出一种亚硝胺类化合物全检测的方法,大幅度减少了现有国家标准对食品中亚硝胺类化合物的漏检.该检测方法原理简单、实验操作方便、测试成本低.

Determination of N-nitrosamine compounds in food by using double-ion probe method of electron impact mass spectrometry

There are over 300 N-nitrosamine compounds found in food, but the current national standards only detect four representative nitrosamine compounds. N-nitrosamine compounds can be ionized and produce two unique fragment ions, nitroso amide (N2O) and nitrosyl (NO), in electron impact (EI) mass spectrometry ionization, and this property is used to determine the existence of nitrosamine compounds and quantify these compounds by selecting the two ions as double-probe signals. The commercially available preserved meat was selected as test objects. A method of determination of N-nitrosamine compounds in food was explored. This method can greatly reduce the missed detection of nitrosamine compounds existing in food. The method is simple in principle and the experiment operation involved is convenient, it greatly cut down the cost of testing.