认知功能障碍的遗传学基础

目的:通过了解具有认知表型病例的遗传学基础,揭示认知的生物学基础.方法:对非特异性精神发育迟滞等具有精神发育迟滞表型的病症的分子基础以及学习与记忆的动物模型的研究成果进行阐述.结果:染色体畸形和基因突变会导致精神发育迟滞.学习与记忆行为与基因的表达及蛋白质的合成相关.结论:精神发育迟滞等病症的分子基础和学习与记忆的动物模型研究的认识,促使我们理解认知的生物学基础.

The genetic basis of cognitive functional obstacle

To learn the biological basis of cognitive processes by recognizing the genetic basis of cases with cognitive phenotypes. Methods Expounding the studies of molecular basis of mental retardation, such as non-secific mental retardation, and the studies of animal models of learning and memory. Results Single-gene disorders and chromosomal abnormalities result in a cognitive abnormality, the learning and memory process associatied with the expressions of gene and protein synthesis. Conclusion The recognition of the molecular basis of mental retardation and the studies of animal models of learning and memory impel us to understand the biological basis of cognition.