| Recent progress in polymer-based gene delivery vectors |
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| 作者姓名： | HUANGShiwen ZHUORenxi |
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| 作者单位： | DepartmentofChemistry,WuhanUniversity,Wuhan430072,China |
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| 基金项目： | 国家重点基础研究发展计划(973计划)，高等学校博士学科点专项科研项目，the Creative Fund of Wuhan University |
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| 摘 要： | The gene delivery system is one of the three components of a gene medicine, which is the bottle neck of current gene therapy. Nonviral vectors offer advantages over the viral system of safety, ease of manufacturing, etc. As important nonviral vectors, polymer gene delivery systems have gained increasing attention and have begun to show increasing promising. In this review, the fundamental and recent progress of polymer-based gene delivery vectors is reviewed.
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| 关 键 词： | 基因治疗 基因转移 内吞作用 质粒DNA |
| 收稿时间： | 2002-08-12 |
| 修稿时间： | 2003-01-24 |
Recent progress in polymer-based gene delivery vectors |
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| HUANGShiwen ZHUORenxi.Recent progress in polymer-based gene delivery vectors[J].Chinese Science Bulletin,2003,48(13):1304-1309. |
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| Authors: | Shiwen Huang Renxi Zhuo |
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| Institution: | e-mail: pibmp@ public.wh.hb.cn |
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| Abstract: | The gene delivery system is one of the three components of a gene medicine, which is the bottle neck of current gene therapy. Nonviral vectors offer advantages over the viral system of safety, ease of manufacturing, etc. As important nonviral vectors, polymer gene delivery systems have gained increasing attention and have begun to show increasing promising. In this review, the fundamental and recent progress of polymer-based gene delivery vectors is reviewed. |
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| Keywords: | gene delivery gene transfer gene therapy polymer vector nonviral vector |
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