实验性交感性眼炎发病机制的研究

以13只白色豚鼠作实验,其中3只为 C 组作对照,另10只分为 A、B 二个组,在以牛晶体蛋白连续皮内注射4次致敏之后,做一只眼的晶体截囊术。术后 A 组皮下注射生理盐水,B 组则皮下注射环孢霉素(Cyclosporine)。结果 A 组发生交感性眼炎,而 B 组和 C 组均未发生。因为环孢霉素具有选择性的抑制 T 淋巴细胞的功能,故推测交感性眼炎的发病机制可能与 T 淋巴细胞的关系极为密切。     

冠状动脉粥样硬化病变中微量元素的X射线显微分析

本文应用EDAX-9100能谱仪,对家兔冠状动脉粥样硬化病变部位的微量元素进行显微分析,发现Zn/Cu比值大于1,提供了冠心病病因中“Zn/Cu假说”的实验论证。     

Muscarinic involvement in vascular and adrenal medullary responses to splanchnic nerve stimulation in conscious calves

Stimulation of the peripheral end of the right splanchnic nerve (4 Hz for 10 min) in the presence of hexamethonium caused a small but significant rise in mean aortic blood pressure which was subsequently abolished by atropine. There were also small but significant increases in the outputs of catecholamines, [Met⁵]-enkephalins and corticotrophin releasing factor (CRF) from the right adrenal gland. The catecholamine response was roughly halved after atropine while the outputs of enkephalins and CRF were unaffected. It is concluded that splanchnic sympathetic postganglionic neurones supplying the vasculature are completely blocked by cholinergic blockade whereas adrenal medullary responses persist in an attenuated form.     

两栖类交感神经节的突触传递

两栖类交感神经节广泛地用于神经生物学研究,包括突触和膜生物物理学研究．交感神经节细胞体积大,细胞的形状简单,无树突,突触位于细胞体上,神经节结构简单,但同时又具有中间神经元,在体外易于长时间存活．两栖动物交感神经节表现出多种突触后电位,包括快兴奋性突触后电位（ｆＥＰＳＰ）,慢抑制性突触后电位（ｓＩＰＳＰ）,慢兴奋性突触后电位（ｓＥＰＳＰ）,晚期慢兴奋性突触后电位（ｌｓＥＰＳＰ）,同时还表现多种突触塑性,说明该神经节具有信息存储功能,因此,两栖动物交感神经节可作为研究学习与记忆的模型系统．