旅游数字足迹研究：热点与展望

在疫情蔓延、经济下行的背景下,开展旅游数字足迹研究,分析预测旅游消费行为,是推进旅游消费发展、推动国际国内经济"双循环"的重要基础工作.作为旅游信息化领域的新兴话题,旅游数字足迹是游客在通讯网络、互联网和物联网等泛在网络上留下的海量电子痕迹,真实反映了游客选择偏好和深层次的行为规律.国内外学者对这方面的研究已取得一定成果,但仍处于探索阶段.鉴于此,本研究辨析了旅游数字足迹的定义、类型和相关概念,阐明了旅游数字足迹的数据来源、特征和应用,分析了旅游数字足迹在游客人口特征、游客人格预测和游客行为分析领域的热点问题.最后,从理论体系构建、数据来源和预测方法精度等问题出发,对旅游数字足迹领域未来的研究方向进行了展望,为持续激发旅游消费潜力、推动旅游消费规模增长提供理论参考.     

Intrinsically disordered proteins in crowded milieu: when chaos prevails within the cellular gumbo

Effects of macromolecular crowding on structural and functional properties of ordered proteins, their folding, interactability, and aggregation are well documented. Much less is known about how macromolecular crowding might affect structural and functional behaviour of intrinsically disordered proteins (IDPs) or intrinsically disordered protein regions (IDPRs). To fill this gap, this review represents a systematic analysis of the available literature data on the behaviour of IDPs/IDPRs in crowded environment. Although it was hypothesized that, due to the excluded-volume effects present in crowded environments, IDPs/IDPRs would invariantly fold in the presence of high concentrations of crowding agents or in the crowded cellular environment, accumulated data indicate that, based on their response to the presence of crowders, IDPs/IDPRs can be grouped into three major categories, foldable, non-foldable, and unfoldable. This is because natural cellular environment is not simply characterized by the presence of high concentration of “inert” macromolecules, but represents an active milieu, components of which are engaged in direct physical interactions and soft interactions with target proteins. Some of these interactions with cellular components can cause (local) unfolding of query proteins. In other words, since crowding can cause both folding and unfolding of an IDP or its regions, the outputs of the placing of a query protein to the crowded environment would depend on the balance between these two processes. As a result, and because of the spatio-temporal heterogeneity in structural organization of IDPs, macromolecular crowding can differently affect structures of different IDPs. Recent studies indicate that some IDPs are able to undergo liquid–liquid-phase transitions leading to the formation of various proteinaceous membrane-less organelles (PMLOs). Although interiors of such PMLOs are self-crowded, being characterized by locally increased concentrations of phase-separating IDPs, these IDPs are minimally foldable or even non-foldable at all (at least within the physiologically safe time-frame of normal PMLO existence).     

An Improved Underwater Confrontation Simulation Method of Naval Amphibious Operational Training System

This paper described an improved underwater confrontation simulation method of naval amphibious operational training system. The initial position of submarine forces on the enemy is generated automatically, and the attacking distance model of torpedoes is established based on the kinematics theory, which is more flexible and reasonable to judge the launch condition compared to traditional method. The two kinds of confrontation behavior models on the enemy submarine are created to depict its tactical action from the defensive to the offensive as well as the contrary, ensuring that operational style is simulated more comprehensively and properly. The existing motion trajectory estimation and collision detection algorithms on operational platforms are also improved to reduce the iteration error and further enhance the detection accuracy of target hit.     

突发事件快速评估模型

突发事件发生初期,进行突发事件的快速综合评估,有利于及时、准确地把握事件的态势,以满足应急决策的时效性要求.为解决突发事件数据量较大,数据更新较快时,过于复杂的运算过程和计算软件缺乏以及已有软件兼容性低而难以满足应急决策的时效性要求的问题,本文简化了Simos过程和PROMETHEEⅡ方法,构建了突发事件快速评估模型,即SSPPM(Simple Simos'Procedure and PROMETHEEⅡModel).为了验证新模型的有效性,本文选取了两个数据进行实验.实验结果表明,在对评估速度的要求大于对精度的要求的突发事件控制阶段,新模型能快速综合多位应急决策者的意见,快速获取权重,简化评估过程,提高突发事件综合评估效率.     

结肠息肉内镜下治疗的体会

目的:探讨结肠息肉内镜下治疗的各种方法及效果.方法:通过肠镜检查8 024例确诊的各种形态、大小息肉1 326例共1 637颗,对于不同大小、形态的息肉,采用单一和联合的内镜治疗.结果:1 326例结肠息肉内镜治疗1 637颗,其中有4例因基底癌变转外科治疗,发生迟发性出血9例,再次内镜下止血成功;穿孔2例,1例钛夹修补成功,1例钛夹修补失败转外科治疗,并发症发生率为0.82%.结论:结肠息肉内镜下治疗是一种安全有效的方法.     

余额宝投资群体分析

随着互联网技术向金融领域的不断延伸,以阿里巴巴推出的余额宝为代表的互联网金融业务尤为引人注目。以问卷调查的方式,阐述了余额宝适用人群的调查信息,分析了余额宝适用人群的特点,为余额宝及互联网金融业的发展提供参考。     

普通话在线游戏学习系统的研究与应用

针对希望进一步掌握普通话口语学习的外国学习者,该研究提出了一种普通话游戏学习系统.系统的学习模式结合了计算机技术和语言学研究成果,打破了传统的教学模式的限制,对学习者进行实时评测,提供学习报告与口语学习的最终评定结果.结果表明,该系统能够较为有效地辅助外国学习者的普通话口语学习.