Estimation of Partially Linear Panel Data Models with Cross-Sectional Dependence

Journal of Systems Science and Complexity - This paper studies the estimation of the partially linear panel data models, allowing for cross-sectional dependence through a common factors structure....     

环境信息披露、技术创新投入与企业高质量发展基于制造业上市公司的经验证据

在我国经济发展进入新常态的背景下，如何推进经济高质量发展成为经济社会发展的主要任务,“创新、协调、绿色、开放、共享”五大发展理念，是实现高质量发展的必由之路。本文从全要素生产率的视角出发，系统地剖析了环境信息披露、技术创新投入对制造业企业发展质量的影响及作用机理，实证结果表明：环境信息披露促进企业高质量发展；技术创新投入具有滞后性，在短期内不会带来企业发展质量的提升；但技术创新投入对环境信息披露与企业发展质量的关系具有正向调节作用；基于产权异质性的结果显示，这种正向调节作用在非国有企业中更显著。     

考虑氯离子侵蚀时变劣化效应的近海斜拉桥地震易损性分析

为研究氯离子侵蚀对近海大型桥梁地震易损性的时变影响规律,以某近海斜拉桥为对象,建立非线性数值模型并开展增量动力分析,获得主塔等构件及桥梁系统的时变易损性曲线.结果表明,材料腐蚀会导致构件及结构的损伤概率出现不同程度的增加.桥梁结构第1阶自振周期对应的谱加速度Sa(T1)为0.3g时,主塔严重损伤的概率在0、25、50、75、100a五种服役时间下分别为0、8.9％、12.1％、22.1％和35.1％.不同构件的损伤概率差异显著,服役时间为100 a,Sa(T1)= 0.15g时,主塔、桥墩、桩、支座、拉索严重损伤的概率分别为0、0、21.0％、97.4％、6.4％.对于轻微损伤、中等损伤及严重损伤状态,系统易损性主要取决于支座的损伤概率;完全破坏状态则主要取决于桩的损伤概率.因此应重视沿海桥梁抗震性能的时变劣化,在桥梁设计中考虑环境侵蚀的影响.     

R型半胱氨酸体系电荷转移百分数的理论计算

采用密度泛函理论中的CAM-B3LYP方法, 在6-31G(d)基组水平上优化气相条件下R型半胱氨酸(R-Cys)分子的几何构型, 理论研究电子激发过程中R-Cys体系片段间的电荷转移特征, 并基于弛豫与非弛豫激发态密度计算片段间的电荷转移百分数. 结果表明: 对于SH片段, S0到S3的电荷转移百分数为57.96%； 对于COOH片段, S0到S1~S5各激发态的电荷转移百分数均为负值, 二者电荷转移的定性结果一致； 对于NH2片段, S0到S1和S4的电荷转移百分数分别为6.98%和31.45%.     

烟支硬度检测结果影响因素分析

为探究烟支硬度检测结果的影响因素,对烟支物理指标检测方案进行优化,提升卷烟质量监督水平.本试验以3类卷烟泰山(东方)为试验材料,分别设计不同检测方案、挡烟板位置、预压时间、压缩时间、压缩速度、环境湿度、贮存时间来对烟支硬度进行测定.烟支检测全项时硬度明显高于单独检测出的硬度;随挡烟板位置的增加,烟支硬度检测值先下降再上升;预压时间、压缩速度对烟支硬度检测结果影响不显著;不同的测试环境湿度会引起烟支水分变化,进而导致烟支硬度检测值产生变化;1个月内硬度不会发生明显变化,但是随着贮存时间延长而增长.应适当优化烟支物理指标检测顺序或方案,设置挡烟板位置为距离接嘴端55 mm,降低测定环境湿度为60％±2％,减少烟支贮存时间或控制贮存环境湿度,及时维护测定设备,以提升质量监督水平.     

乡村振兴绩效评价:意义、维度与路径

2018年,中共中央、国务院印发《中国乡村振兴战略规划(2018-2022年)》,全面部署和布局乡村振兴战略.文章基于政府绩效评价的理念和方法,构建乡村振兴绩效评价指标体系,明确评价维度,为实现乡村振兴、城乡融合发展提供价值导向、度量体系和动力工具.该评价维度包涵资源投入、过程监管、目标实现情况和社会满意度四个方面.文章指出,相关单位以绩效评价推进乡村振兴时应注重顶层设计,强化部门协同,构建评价体系,引入第三方评价主体,凸显农民获得感.     

The TET enzymes

During the past decade, we have learnt that the most common DNA modification, 5-methylcytosine (5mC), playing crucial roles in development and disease, is not stable but can be actively reversed to its unmodified form via enzymatic catalysis involving the TET enzymes. These ground-breaking discoveries have been achieved thanks to technological advances in the detection of the oxidized forms of 5mC and to the boldness of individual scientists. The TET enzymes require molecular oxygen for their catalysis, making them important targets for hypoxia research. They also require special cofactors which enable additional levels of regulation. Moreover, mutations and other genetic alterations in TETs are found, especially in myeloid malignances. This review focuses on the kinetic and inhibitory properties of the TET enzymes and the role of TETs in cellular differentiation and transformation and in cancer.     

Current knowledge on exosome biogenesis and release

Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, with the plasma membrane. This process was discovered more than 30 years ago, and during these years, exosomes have gone from being considered as cellular waste disposal to mediate a novel mechanism of cell-to-cell communication. The exponential interest in exosomes experienced during recent years is due to their important roles in health and disease and to their potential clinical application in therapy and diagnosis. However, important aspects of the biology of exosomes remain unknown. To explore the use of exosomes in the clinic, it is essential that the basic molecular mechanisms behind the transport and function of these vesicles are better understood. We have here summarized what is presently known about how exosomes are formed and released by cells. Moreover, other cellular processes related to exosome biogenesis and release, such as autophagy and lysosomal exocytosis are presented. Finally, methodological aspects related to exosome release studies are discussed.