全自动高清智能录播教室建设研究——以福建卫生职业技术学院为例

结合福建卫生职业技术学院建设全自动高清智能录播教室实践,研究和总结在录播教室室内装修需注意的问题及解决措施,并对录播教室需要配备的多媒体教学设备、视音频信息采集、师生的跟踪定位、录播导播等提出建议。     

Phytanic acid impairs mitochondrial respiration through protonophoric action

Refsum disease is a rare, inherited neurodegenerative disorder characterized by accumulation of the dietary branched-chain fatty acid phytanic acid in plasma and tissues caused by a defect in the alphaoxidation pathway. The accumulation of phytanic acid is believed to be the main pathophysiological cause of the disease. However, the exact mechanism(s) by which phytanic acid exerts its toxicity have not been resolved. In this study, the effect of phytanic acid on mitochondrial respiration was investigated. The results show that in digitonin-permeabilized fibroblasts, phytanic acid decreases ATP synthesis, whereas substrate oxidation per se is not affected. Importantly, studies in intact fibroblasts revealed that phytanic acid decreases both the mitochondrial membrane potential and NAD(P)H autofluorescence. Taken together, the results described here show that unesterified phytanic acid exerts its toxic effect mainly through its protonophoric action, at least in human skin fibroblasts. Received 4 August 2007; received after revision 26 September 2007; accepted 10 October 2007 J. C. Komen, F. Distelmaier: These authors contributed equally to this work.     

Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications

Glycosylation constitutes one of the most important posttranslational modifications employed by biological systems to modulate protein biophysical properties. Due to the direct biochemical and biomedical implications of achieving control over protein stability and function by chemical means, there has been great interest in recent years towards the development of chemical strategies for protein glycosylation. Since current knowledge about glycoprotein biophysics has been mainly derived from the study of naturally glycosylated proteins, chemical glycosylation provides novel insights into its mechanistic understanding by affording control over glycosylation parameters. This review presents a survey of the effects that natural and chemical glycosylation have on the fundamental biophysical properties of proteins (structure, dynamics, stability, and function). This is complemented by a mechanistic discussion of how glycans achieve such effects and discussion of the implications of employing chemical glycosylation as a tool to exert control over protein biophysical properties within biochemical and biomedical applications. Received 15 December 2006; received after revision 28 March 2007; accepted 25 April 2007     

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422 controls. Outside the HLA region, the most significant finding (rs13119723; P = 2.0 x 10(-7)) was in the KIAA1109-TENR-IL2-IL21 linkage disequilibrium block. We independently confirmed association in two further collections (strongest association at rs6822844, 24 kb 5' of IL21; meta-analysis P = 1.3 x 10(-14), odds ratio = 0.63), suggesting that genetic variation in this region predisposes to celiac disease.     

一类次二次Hamilton系统的次调和解的存在性

运用临界点理论中的极小极大方法得到一类次二次Hamilton系统的次调和解的存在性定理.     

软件补偿方法在测温智能仪表中的应用

软件补偿方法具有效果好、精确度高、成本低的优点。介绍了在研制多点巡回检测仪中采用的几种软件补偿方法：前向通道特性补偿使放大器等元件不因外界条件的变化而受到任何影响；引线电阻的补偿可实现引线电阻对系统无任何影响；热电阻、热电偶的非线性度补偿效果明显，节省开销。     

MC68HC705PA6A在电梯门安全保护光幕装置中的应用

本文介绍了MC68HC705P6A单片机在电梯门安全保护光幕中的作用，以及电梯门安全保护光幕的工作原理，电路设计和软件设计。     

用鸡蛋壳膜生产高级化妆品

日本东洋化妆品公司,用鸡蛋壳膜(凤凰衣)生产高级化妆品。其工艺是:将蛋壳碾碎成颗粒状,用一公斤蛋壳渣,浸泡在24升浓度为5％的醋酸水溶液里,浸泡24小时后,再加入10％的醋酸水溶液6公斤,浸泡24小时后,蛋壳渣溶解沉淀,壳膜(卵膜)则浮在溶液的表面,用过滤法,得到表层的卵膜,经干燥磨粉,可得到85克卵膜粉。这种卵膜粉溶于水,用来调成护肤霜,具有使皮肤细腻光滑等功效,比用珍珠粉可降低成本85％。     

地方职业大学师资队伍建设及其对策

职业大学师资队伍经过十几年的建设,已经有一定规模,取得了可喜的成绩。但在如何进一步加强建设有地方职业大学特色的师资队伍这个问题上,仍有待于进一步探索。本文就比结合实际谈几点粗浅的看法。     

SQL多表外连接查询

介绍了外连接查询的意义、外连接查询的实现步骤和方法，着重指出：SQL对一父多子的多个表进行外连接查询时，要特别注意FROM子句中连接对象和连接条件的先后位置。当子表中符合连接条件的记录有多条时，不要在SQL—SELECT语句中用SUMO函数和GROUP BY子句实现分组汇总，应汇总后再连接。否则，会导致汇总数据的错误，并且执行时间也大大增加。需对结果中值为NUIL的字段进行数学运算时。要对其进行替换处理。