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Konacki M  Torres G  Jha S  Sasselov DD 《Nature》2003,421(6922):507-509
Planets orbiting other stars could in principle be found through the periodic dimming of starlight as a planet moves across--or 'transits'--the line of sight between the observer and the star. Depending on the size of the planet relative to the star, the dimming could reach a few per cent of the apparent brightness of the star. Despite many searches, no transiting planet has been discovered in this way; the one known transiting planet--HD209458b--was first discovered using precise measurements of the parent star's radial velocity and only subsequently detected photometrically. Here we report radial velocity measurements of the star OGLE-TR-56, which was previously found to exhibit a 1.2-day transit-like light curve in a survey looking for gravitational microlensing events. The velocity changes that we detect correlate with the light curve, from which we conclude that they are probably induced by an object of around 0.9 Jupiter masses in an orbit only 0.023 au from its star. We estimate the planetary radius to be around 1.3 Jupiter radii and its density to be about 0.5 g x cm(-3). This object is hotter than any known planet (approximately 1,900 K), but is still stable against long-term evaporation or tidal disruption.  相似文献   
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Effect of doses of the X-ray radiation from 0 to 400 Gy upon granular cornstarch and dextrins (British gums, BG) thermally generated from it at 230--300℃ was recognized with quantitative EPR and IR absorption spectroscopy, molecular mass distribution in the depolymerization products, Scanning Electron Microscopy, and X-ray diffractometry. Fractal analysis of the profiles of molecular mass distribution showed that the depolymerization involved debranching of amylopectin. Roasting of cornstarch produced BG which differed in concentration and EPR parameters of stable free radicals from BG generated by X-ray radiation. Two types of stable free radicals, with Gaussian and Lorentzian shapes of EPR signals, were recognized. The shapes of the signals and temperature dependence on free radical intensity indicated exchanging interactions of the antiferromagnetic type, causing partial quenching of the spins at-196℃(77K). Upon X-ray irradiation, new radicals were generated, the number and stability of which strongly depended on the types of radicals present before irradiation. These radicals slowly ceased because of a repolymerization of BG on storage.  相似文献   
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The discoidin domain receptors (DDRs) are collagen-binding receptor tyrosine kinases that have been implicated in a number of fundamental biological processes ranging from growth and development to immunoregulation. In this review, we examine how recent proteomic technologies have enriched our understanding of DDR signaling mechanisms. We provide an overview on the use of large-scale proteomic profiling and chemical proteomics to reveal novel insights into DDR therapeutics, signaling networks, and receptor crosstalk. A perspective of how proteomics may be harnessed to answer outstanding fundamental questions including the dynamic regulation of receptor activation kinetics is presented. Collectively, these studies present an emerging molecular portrait of these unique receptors and their functional role in health and disease.  相似文献   
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Konacki M 《Nature》2005,436(7048):230-233
Hot Jupiters are gas-giant planets orbiting with periods of 3-9 days around Sun-like stars. They are believed to form in a disk of gas and condensed matter at or beyond approximately 2.7 astronomical units (au-the Sun-Earth distance) from their parent star. At such distances, there exists a sufficient amount of solid material to produce a core capable of capturing enough gas to form a giant planet. Subsequently, they migrate inward to their present close orbits. Here I report the detection of an unusual hot Jupiter orbiting the primary star of a triple stellar system, HD 188753. The planet has an orbital period of 3.35 days and a minimum mass of 1.14 times that of Jupiter. The primary star's mass is 1.06 times that of the Sun, 1.06 M(\circ). The secondary star, itself a binary stellar system, orbits the primary at an average distance of 12.3 au with an eccentricity of 0.50. The mass of the secondary pair is 1.63 M(\circ). Such a close and massive secondary would have truncated a disk around the primary to a radius of only approximately 1.3 AU (ref. 4) and might have heated it up to temperatures high enough to prohibit giant-planet formation, leaving the origin of this planet unclear.  相似文献   
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