统一碳税和差异化碳税下的再制造绩效评价

分别在无碳税、统一碳税和差异化碳税三种政策下,构建了垄断制造商的利润最大化决策模型,研究实施不同碳税政策对制造商的再制造生产决策、碳排放和社会福利的影响.研究表明:相比于无碳税政策,政府征收碳税减少了制造商的利润和碳排放,在一定条件下有利于提高社会福利;实施碳税政策有利于鼓励更多类型的制造商参与再制造,并且差异化碳税比统一碳税具有更大的灵活性.进一步地,结合理论比较和数值试验,研究了政府在统一碳税的基础上分别做单向和双向差异化碳税调整后的绩效变化情况,结论表明:统一碳税与差异化碳税不存在绝对占优的碳税形式.政府应根据再制造品特点、单位环境污染损失、统一碳税基准水平和调整幅度等特点,采取合理的碳税调整方式以优化社会福利.     

2021年经济景气形势监测、分析和预测

我国经济增长在遭遇前所未有的疫情冲击后进入为期一年的超常快速扩张期，并于2021年2月形成扩张高峰，此后转入经济周期收缩阶段。2020年11月至2021年7月经济运行已恢复至“正常”景气区间，但需求端的恢复弱于供给端。2021年3季度的综合警情指数明显下滑，发出“偏冷”预警信号，且4季度可能继续下行,但物价总体保持稳定。预计全年GDP增长8.1%左右（两年平均增长5.2%左右），全年CPI上涨0.9%左右。建议宏观调控应做好跨周期设计，注意处理好稳增长、防风险和节能环保的关系，提高疫情应对的精准性，适度加大稳增长力度，努力保持经济在合理区间的平稳运行。     

Post李超代数结构的性质

通过post李超代数的定义, 讨论post李超代数结构的基本性质, 给出post李超代数的一些存在性结果, 并利用post李超代数可构造LR超代数和左对称超代数, 给出交换post李超代数结构的相关结果.     

人丝氨酸蛋白酶抑制剂B3基因的生物信息学分析

人丝氨酸蛋白酶抑制剂B3 SERPINB3能抑制半胱氨酸蛋白酶,具有抗细胞调亡、促进细胞增殖和迁移作用,且与许多肿瘤的发生与发展密切相关.通过基因电子克隆(in silico cloning)获得SERPINB3基因全长cDNA序列(1779 bp),编码由390个氨基酸组成的蛋白质.核酸序列分析表明:SERPINB3基因位于人体18号染色体长臂(18q21.33),基因组跨越80373285 bp,含有个16外显子,15个内含子,其cDNA序列上总共有45个酶切位点.SERPINB基因核酸序列同源性分析显示,人类与黑猩猩的亲缘关系较近,与白眉猴和猕猴的亲缘关系是最远.SERPINB3蛋白序列同源性分析显示,人类和黑猩猩亲缘关系较近,和苍疣猴亲缘关系较远.SERPINB3相互作用蛋白的生物信息学分析表明:与SERPINB3相互作用的蛋白中,以丝氨酸蛋白酶家族成员居多,且大多在调节炎症反应、细胞增殖分化以及凋亡等方面起着关键作用.本论文通过对SERPINB3基因的生物信息学分析,为SERPINB3的功能和分子进化研究提供更多的生物信息学参考.     

The TET enzymes

During the past decade, we have learnt that the most common DNA modification, 5-methylcytosine (5mC), playing crucial roles in development and disease, is not stable but can be actively reversed to its unmodified form via enzymatic catalysis involving the TET enzymes. These ground-breaking discoveries have been achieved thanks to technological advances in the detection of the oxidized forms of 5mC and to the boldness of individual scientists. The TET enzymes require molecular oxygen for their catalysis, making them important targets for hypoxia research. They also require special cofactors which enable additional levels of regulation. Moreover, mutations and other genetic alterations in TETs are found, especially in myeloid malignances. This review focuses on the kinetic and inhibitory properties of the TET enzymes and the role of TETs in cellular differentiation and transformation and in cancer.     

Current knowledge on exosome biogenesis and release

Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, with the plasma membrane. This process was discovered more than 30 years ago, and during these years, exosomes have gone from being considered as cellular waste disposal to mediate a novel mechanism of cell-to-cell communication. The exponential interest in exosomes experienced during recent years is due to their important roles in health and disease and to their potential clinical application in therapy and diagnosis. However, important aspects of the biology of exosomes remain unknown. To explore the use of exosomes in the clinic, it is essential that the basic molecular mechanisms behind the transport and function of these vesicles are better understood. We have here summarized what is presently known about how exosomes are formed and released by cells. Moreover, other cellular processes related to exosome biogenesis and release, such as autophagy and lysosomal exocytosis are presented. Finally, methodological aspects related to exosome release studies are discussed.     

Study on the Centralization Strategy of the Blood Allocation Among Different Departments within a Hospital

By far, the researches on how to distribute blood products among different departments in hospital have not been further studied, though the problem of blood shortage and wastage that caused by improper blood allocation is severe, which may endanger patient’s lives and impose considerable costs on hospitals. In order to solve this problem, this paper mainly studies on how to distribute the blood items among different departments within a hospital and investigates the allocation approach with the novel management method by centralizing the inventory of several different departments. By integrating the blood inventory requirements of some departments, the hospital could reduce the rate of blood shortage and wastage effectively, release the pressure of the occupancy of resources and reduce the bullwhip effect of blood products. This paper illustrates the centralization principle in hospital and formulates the mixed integer programming model to work out the optimal allocation network scheme and the optimal inventory setting for every department. And the results of the numerical example demonstrate that this centralization method could considerably reduce blood shortage and wastage in hospital by about 72% and 90% respectively. Furthermore, it could decrease the total cost by about 108,540 RMB a month on blood supply chain management in the hospital and improve the effect of some certain surgeries by transfusing the fresh blood to patients.     

Fuzzy Views on Black-Litterman Portfolio Selection Model

In this paper, views of investor are described in fuzzy sets, and two fuzzy Black-Litterman models are constructed with fuzzy views and fuzzy random views respectively. In the models, expected returns and uncertainty matrix of views are redefined and the views are formulated by fuzzy approaches suitably. Then the models are tested with data from Chinese financial markets. Empirical results show that the fuzzy random views model performs the best, and both the fuzzy models are better than the traditional ones, demonstrating that the fuzzy approaches can contain more information in the views and measure the uncertainty more correctly.