Voice Recognition by Neuro-Heuristic Method

The amount of digital data is increasing every day. At every step of our daily lives, we deal with technologies in which our data are stored(e.g., mobile phones and laptops), and this is one of the main reasons for the design of various types of encryption and user identity verification algorithms. These algorithms are meant not only to fulfill the desire of protecting data but also to address the possibility of granting access of specific digital data to selected individuals. This process brings with it the problem of identity verification. This paper discusses the problem of voice verification and presents a voice verification method based on artificial intelligence methods.Numerous tests are performed herein to demonstrate the effectiveness of the presented solution. The research results are shown and discussed in terms of the advantages and disadvantages of the solution.     

Whole genome sequencing as a means to assess pathogenic mutations in medical genetics and cancer

The past decade has seen the emergence of next-generation sequencing (NGS) technologies, which have revolutionized the field of human molecular genetics. With NGS, significant portions of the human genome can now be assessed by direct sequence analysis, highlighting normal and pathological variants of our DNA. Recent advances have also allowed the sequencing of complete genomes, by a method referred to as whole genome sequencing (WGS). In this work, we review the use of WGS in medical genetics, with specific emphasis on the benefits and the disadvantages of this technique for detecting genomic alterations leading to Mendelian human diseases and to cancer.     

内部控制对公司价值的影响——基于关联交易的中介效应检验

以2010—2017年沪深两市上市公司为样本，基于关联交易视角，采用中介效应检验方法，从对外关联担保、对外提供资金和非公允关联购销3个角度，系统考察内部控制对公司价值的影响及影响机理。研究结果表明:健全的内部控制能显著提升公司价值，良好的内部控制能够抑制对外关联担保，进而提高公司价值，内部控制对外提供资金和非公允关联购销对公司价值没有显著影响；内部控制主要通过抑制关联担保提升公司价值；内部控制对公司价值的影响不随监管强度、市场化程度和产权性质的变化而变化；内部控制对关联担保的抑制作用，仅在内部控制建设监管较严时、市场化程度较高的地区存在。     

铸造工艺仿真设计前处理及过程处理应用技术

以应用ProCAST和MAGMAsoft 2款软件为例，针对铸造工艺仿真设计前处理和过程处理每个环节的主要内容与使用方法进行了较为详细地归纳、分析和总结。提出了处理过程的技术路线，并系统地介绍了每项应用内容的操作平台与使用步骤，从而为高效地应用铸造工艺仿真设计提供理论和技术支持。     

Design and research of torque tube used in HTS motor

In order to improve the overall performance of high temperature superconducting （HTS） motor, a radial connection torque tube with high strength and low thermal leakage has been designed. Firstly, fiberglass epoxy composite is chosen as con- struction material. The structural size of the torque tube is obtained by means of load analysis and theoretical calculation. Secondly, thermal leakage of the torque tube is calculated with both theo- retical method and 3D finite-element analysis （FEA）. According to the result of the thermal analysis and mechanical loads, the struc- tural stresses of the torque tube are also obtained by FEA method. Lastly, a low temperature test platform is developed to verify the strength and the thermal leakage of the torque tube. The results show that the maximal shear stress of the torque tube is 24.3 MPa and thermal leakage of torque tube is 10.5 W, which satisfy the design requirements of the HTS motor. The torque tube also works in good condition at full-power and full-torque testing of the motor. The design method is also applicable for other similar design of torque tube in other applications.     

Technique for advanced electrochemical oxidation treatment of nanofiltration concentrate of landfill leachate

Landfill leachate treated with combined process of ＂pretreatment ＋biological treatment ＋advanced treatment （NF）＂ to produce nanofiltration concentrate, which bio-chemical ratio （B/C） is less than 0.1 and CODer concentration is 2 000-2 500 mg/L, high salt content. Which cannot be discharged under existing environ- mental standards. According to analysis based on electrochemical advanced oxidation mechanism, a two-step electrochemical tech- nique was recommended. In the first step, a pulse electrochemical technique was adopted. With Fe as consumption electrode and current density of 10 mA/cm2, the pollutants were removed by means of Fenton reaction, electroflotation and electrocoagulation. In the second step, a double function electrode was used to per- form electrocatalytic oxidation by means of titanium metallic oxi- dates. In the condition that current density being 12.5 mA/cm2, the pollutants were further removed by oxidation and electrolytic deposition. Result shows that the removing rate of CODer, NH3-N and CI were 70%-85%, 90% and 25%, respectively; average value of B/C ratio increased from 0.09 to 0.38 and conductivity reduced by 10%.     

基于结构状态方程的结构参数和荷载识别方法

基于结构状态方程进行结构参数和荷载的共同识别。以结构参数修正因子为优化变量,由测得的结构动态响应结构和构造的系统矩阵计算相应的未知荷载。通过最小化实测结构响应与给定的修正因子下的计算结构响应间的距离来识别未知量。其中给定修正因子的系统矩阵由虚拟变形方法构造,并通过一个桁架结构的数值算例验证了该方法的有效性。     

The wedge and the vis viva controversy: how concepts of force influenced the practice of early eighteenth-century mechanics

This article discusses the quest for the mechanical advantage of the wedge in the eighteenth century. As a case study, the wedge enlightens our understanding of eighteenth-century mechanics in general and the controversy over “force” or vis viva in particular. In this article, I show that the two different approaches to mechanics, the one that favoured force in terms of velocities and the one that primarily used displacements—known as the ‘Newtonian’ and ‘Leibnizian’ methods, respectively—were not at all on par in their ability to solve the problem of the wedge. In general, only those who used the Leibnizian concept of force or some related notion were able to get to the conventional results. This article thus rebuts the received view that the vis viva controversy was merely a semantic one. Instead, it shows that different understandings of “force” led to real and pragmatic differences in eighteenth-century mechanics.     

Mesenchymal–epithelial interactions during digestive tract development and epithelial stem cell regeneration

The gastrointestinal tract develops from a simple and uniform tube into a complex organ with specific differentiation patterns along the anterior–posterior and dorso-ventral axes of asymmetry. It is derived from all three germ layers and their cross-talk is important for the regulated development of fetal and adult gastrointestinal structures and organs. Signals from the adjacent mesoderm are essential for the morphogenesis of the overlying epithelium. These mesenchymal–epithelial interactions govern the development and regionalization of the different gastrointestinal epithelia and involve most of the key morphogens and signaling pathways, such as the Hedgehog, BMPs, Notch, WNT, HOX, SOX and FOXF cascades. Moreover, the mechanisms underlying mesenchyme differentiation into smooth muscle cells influence the regionalization of the gastrointestinal epithelium through interactions with the enteric nervous system. In the neonatal and adult gastrointestinal tract, mesenchymal–epithelial interactions are essential for the maintenance of the epithelial regionalization and digestive epithelial homeostasis. Disruption of these interactions is also associated with bowel dysfunction potentially leading to epithelial tumor development. In this review, we will discuss various aspects of the mesenchymal–epithelial interactions observed during digestive epithelium development and differentiation and also during epithelial stem cell regeneration.