地方院校基础课物理化学实验教学中的问题及对策

物理化学实验是一门集数学、物理、化学于一体的必修综合性技能课程，起着连接基础学科、应用学科及科学研究的作用。该文结合地方院校的物理化学实验过程教学内容、实验数据处理、学生对仪器设备的使用等教学环节及考核方式，同时对学生心理情况进行了分析，再对教学中出现的问题进行了阐述，并提出通过循环式教学、加强实验技能及设置开放式实验等方法提高教学质量，在教学过程中注重培养学生的动手操作能力，适应了目前应用型人才培养模式。     

渤海L油田早期注聚效果评价方法研究

目前对于早期注聚效果的评价没有成熟的方法,增油降水的效果基本依靠动态分析方法评价,由于早期注聚与晚期注聚的很大不同,造成动态分析方法在评价早期注聚效果方面存在很大的局限性。本文引入一种早期注聚效果评价的新方法,运用数值模拟技术对渤海L早期注聚效果进行全面的评价,建立高精度历史拟合的数值模型,并建立假想的水驱模型,使之与实际模型对比,结果表明,通过数值模拟法计算的增油量与动态分析法相比更加精确,原因是数值模拟法排除了各种措施带来的干扰,且考虑了油田的递减规律。另外建立了不同含水时机注聚的模型,通过分析认为,目前渤海L油田实行的早期注聚在各方面相较其他含水时机注聚具有很大优势。     

含油污泥微生物堆制处理研究

采用微生物堆制法对延长油田含油污泥进行处理,以除油率为指标,分别研究了不同菌种、接种量、调理剂及堆制时间等因素对处理效果的影响.结果表明:增加堆制时间与接种量,除油率提高.经过35 d堆制处理,YC-1菌与YC-13菌的除油率分别达43.41%和54.02%.YC-1菌采用土作为调理剂时除油率为40.01%,优于采用土+荞麦皮的19.05%,而YC-3菌采用土+荞麦皮作为调理剂时除油率为32.55%,略优于采用土作为调理剂的25.38%.     

基于车灯的无线反馈非接触供电电路设计

为了能在汽车的引擎盖等活动部位装设车灯,给出了一种无线反馈稳压的非接触供电车灯电路.无线反馈稳压电路通过无线反馈控制电路的输出电压,达到稳定负载功率的目的,实验证明电路可行.     

Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm

A high-density haplotype map recently enabled a genome-wide association study (GWAS) in a population of indica subspecies of Chinese rice landraces. Here we extend this methodology to a larger and more diverse sample of 950 worldwide rice varieties, including the Oryza sativa indica and Oryza sativa japonica subspecies, to perform an additional GWAS. We identified a total of 32 new loci associated with flowering time and with ten grain-related traits, indicating that the larger sample increased the power to detect trait-associated variants using GWAS. To characterize various alleles and complex genetic variation, we developed an analytical framework for haplotype-based de novo assembly of the low-coverage sequencing data in rice. We identified candidate genes for 18 associated loci through detailed annotation. This study shows that the integrated approach of sequence-based GWAS and functional genome annotation has the potential to match complex traits to their causal polymorphisms in rice.     

自调式镦压挤胀复合液压机的研制

从力学原理、设计原理、整机结构、关键零部件的设计和工作程序，系统地介绍了自调式镦压挤胀复合液压机．由于压机设计了顶出缸对下活动横梁调节限位结构，回程拉杆对上镦压横梁的复位结构及镦压缸和气液储能器之间的连通协调结构，这不仅使该液压机结构紧凑，同时节省了上镦压横梁的回程液压缸、下活动横梁的镦压缸，并简化了上凸模与上镦压模分设的液压系统，而且解决了直齿圆柱齿轮在塑性成形过程中齿顶难以充满、齿根易出现微裂纹，以及成形压力过大和模具寿命过低的问题．     

Impact of bolus volume on small intestinal intra-luminal impedance in healthy subjects

AIM: To assess the impact of bolus volume on the characteristics of small intestinal (SI) impedance signals.METHODS: Concurrent SI manometry-impedance measurements were performed on 12 healthy volunteers to assess the pattern of proximal jejunal fluid bolus movement over a 14 cm-segment.Each subject was given 34 boluses of normal saline (volume from 1 to 30 mL) via the feeding tube placed immediately above the proximal margin of the studied segment.A bolus-induced impedance event occurred if there was > 12%...     

浅埋暗挖工法比选数值模拟分析

地铁开挖对邻近管线的影响已成为地铁工程中的重点问题.文章结合西安地铁二号线,模拟了CD、CRD法开挖对既有给水管影响变形的全过程,通过计算分析比较得出了较为合理的开挖和支护方法,供类似工程参考.     

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms.

The stable propagation of genetic information requires that the entire genome of an organism be faithfully replicated once and only once each cell cycle. In eukaryotes, this replication is initiated at hundreds to thousands of replication origins distributed over the genome, each of which must be prohibited from re-initiating DNA replication within every cell cycle. How cells prevent re-initiation has been a long-standing question in cell biology. In several eukaryotes, cyclin-dependent kinases (CDKs) have been implicated in promoting the block to re-initiation, but exactly how they perform this function is unclear. Here we show that B-type CDKs in Saccharomyces cerevisiae prevent re-initiation through multiple overlapping mechanisms, including phosphorylation of the origin recognition complex (ORC), downregulation of Cdc6 activity, and nuclear exclusion of the Mcm2-7 complex. Only when all three inhibitory pathways are disrupted do origins re-initiate DNA replication in G2/M cells. These studies show that each of these three independent mechanisms of regulation is functionally important.     

将纯框架结构改为底框住宅的设计实例

本文结合具体工程实例，论述了如何将纯框架结构改建成底框住宅以及如何使新旧结构有效联结的方法，讨论了改建工程中值得注意的一些问题。