CONFLICT ANALYSIS OF CITARUM RIVER BASIN POLLUTION IN INDONESIA： A DRAMA-THEORETIC MODEL

The need to manage water resource within a holistic approach is crucial in Indonesia. Conflict situation which involves a variety of stakeholder needs an appropriate methodology to handle it. The purpose of this paper is to provide an integrated framework of a river basin pollution case in Indonesia. This research try to obtain an understanding of the complexity of inter-relationship between stakeholders of the Citarum River Basin and to give feasible recommendations based on a new developed integrated framework. We first describe the problem in a comprehensive way, then develop a framework to analyze the conflict. Next, we propose a general procedure to apply it, which we call Drama-theoretic Dilemma Analysis (DtDA). After analyzing the conflicts that arise there between stakeholders using DtDA, we will show how to resolve the dilemmas by using holistic as well as intensive approaches. By applying DtDA in stakeholder analysis and resolving the dilemmas that arise in the interactions between them, we can identify barriers for collaboration.     

The genome of the protist parasite Entamoeba histolytica

Entamoeba histolytica is an intestinal parasite and the causative agent of amoebiasis, which is a significant source of morbidity and mortality in developing countries. Here we present the genome of E. histolytica, which reveals a variety of metabolic adaptations shared with two other amitochondrial protist pathogens: Giardia lamblia and Trichomonas vaginalis. These adaptations include reduction or elimination of most mitochondrial metabolic pathways and the use of oxidative stress enzymes generally associated with anaerobic prokaryotes. Phylogenomic analysis identifies evidence for lateral gene transfer of bacterial genes into the E. histolytica genome, the effects of which centre on expanding aspects of E. histolytica's metabolic repertoire. The presence of these genes and the potential for novel metabolic pathways in E. histolytica may allow for the development of new chemotherapeutic agents. The genome encodes a large number of novel receptor kinases and contains expansions of a variety of gene families, including those associated with virulence. Additional genome features include an abundance of tandemly repeated transfer-RNA-containing arrays, which may have a structural function in the genome. Analysis of the genome provides new insights into the workings and genome evolution of a major human pathogen.