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对苏州河底泥样品采用正己烷∶丙酮(1∶1)索氏提取,萃取液经浓缩分段后加入内标物萘、菲、艹屈,测定并计算各多环芳烃保留指数,结合GC/MS法,从该底质中鉴别出45种多环芳烃及同分异构体.多环芳烃保留指数与文献相符 相似文献
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Fabrication of PLGA coated silica nanorattle for controlling the drug release behavior 总被引:1,自引:0,他引:1
Silica nanorattle with hollow and mesoporous structure has been proven to be an excellent drug carrier.However,how to control the drug release from silica nanorattle is still a challenge.In this study,we designed two methods,in-situ polymerization method and water in oil in water(W/O/W) double emulsion method,to coat a nanosized poly(lactic-co-glycolic acid)(PLGA) layer onto the surface of silica nanorattle for controlling the drug release behavior.Hydrophobic antitumor drug docetaxel was loaded into the PLGA coated silica nanorattle(PLGA@SN).The drug release profile,cellular uptake and cytotoxicity on human liver cancer HepG2 cells were evaluated to prove that the PLGA layer plays an effective role in tuning the drug delivery. 相似文献
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