String theory,Einstein, and the identity of physics: Theory assessment in absence of the empirical

String theorists are certain that they are practicing physicists. Yet, some of their recent critics deny this. This paper argues that this conflict is really about who holds authority in making rational judgment in theoretical physics. At bottom, the conflict centers on the question: who is a proper physicist? To illustrate and understand the differing opinions about proper practice and identity, we discuss different appreciations of epistemic virtues and explanation among string theorists and their critics, and how these have been sourced in accounts of Einstein's biography. Just as Einstein is claimed by both sides, historiography offers examples of both successful and unsuccessful non-empirical science. History of science also teaches that times of conflict are often times of innovation, in which novel scholarly identities may come into being. At the same time, since the contributions of Thomas Kuhn historians have developed a critical attitude towards formal attempts and methodological recipes for epistemic demarcation and justification of scientific practice. These are now, however, being considered in the debate on non-empirical physics.     

基于半圆阵的解模糊技术研究

传统的干涉仪测向解模糊方法要求特定的天线阵列形式,其应用容易受到可利用体积的限制.针对传统测向解模糊方法在实际系统应用中的问题,提出了任意基线测向原理并建立了任意基线测向模型.对建立模型的镜像模糊问题、多值模糊问题进行了分析并且提出了解决方法.为解决被动雷达多模复合制导导引头体积受限的问题建立了半圆阵天线阵列模型.时建立的模型进行了Matlab仿真,验证了方案的可行性.     

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422 controls. Outside the HLA region, the most significant finding (rs13119723; P = 2.0 x 10(-7)) was in the KIAA1109-TENR-IL2-IL21 linkage disequilibrium block. We independently confirmed association in two further collections (strongest association at rs6822844, 24 kb 5' of IL21; meta-analysis P = 1.3 x 10(-14), odds ratio = 0.63), suggesting that genetic variation in this region predisposes to celiac disease.     

Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum.

Shiga toxin and some other protein toxins that act on targets in the cytosol have previously been shown to enter the trans-Golgi network. Transport by this route may be necessary for translocation of the toxin to the cytosol and for intoxication, but it is not known whether the enzymatically active part of the toxins actually enters the cytosol from the trans-Golgi network. It has been suggested that such toxins are transported in a retrograde manner to the endoplasmic reticulum and that translocation occurs in this organelle, but retrograde transport of endocytosed material beyond the trans-Golgi network has never been demonstrated. Here we show that in butyric acid-treated A431 cells endocytosed Shiga toxin is not only transported to the trans-Golgi network, but also to all Golgi stacks, to the endoplasmic reticulum and to the nuclear envelope. Furthermore, butyric acid sensitizes the cells to Shiga toxin, which is consistent with the possibility that retrograde transport is required for translocation of the toxin to the cytosol.     

基于改进 HAF的线性调频雷达信号参数估计

针对多项式相位信号(PPS)中的线性调频(LFM)雷达信号参数估计,通过提出频谱方差极大值准则对PPS次优参数估计方法高阶模糊度函数(HAF)进行了改进,提出了适于单分量LFM参数估计的改进HAF。首先讨论了HAF对LFM参数的估计方法及其局限性,然后提出了分段频谱方差极大值法则下LFM调频斜率估计的方法,将其与HAF相结合提出了单分量LFM参数估计的改进HAF,克服了接收信号与实际信号起点不一致性对HAF带来的影响,降低了由于HAF局限性带来的调频斜率估计误差,改善了HAF的累积误差效应。MATLAB仿真验证了改进方法较HAF的优越性。     

平面图形设计中符号学原理的应用

图形设计作为视觉传达设计中的一种符号设计现象,其成功所在,是能得以运用设计的符号学原理不断挖掘其深处的潜质,并与人们内心深处的情感相沟通。因此,应该对此进行研究与认识,发掘更多的符号特性,更准确的运用符号学原理来进行平面图形设计。     

对抗体系的一种建模方法研究

首先,通过实例阐明了信息交互在效能涌现中所起的重要作用;其此,提出了“基于信息关联网的体系建模方法”,为研究信息交互过程中对抗体系的效能涌现机理提供了方法论意义上的支持;最后,基于上述体系建模方法,给出了一个具体的建模实例。     

基于图示评审技术的风险投资组合模型

运用系统论和GERT网络理论的思想及其原理,揭示了组合中各项目之间的组合规律,提出了风险投资组合的串联、并联和混联这3种不同的组合模式,构建了其风险与周期评估的组合GERT网络模型,为更加深入地理解与正确客观地把握风险投资状态提供了算法模型和理论依据。     

改进地区生产总值核算的对策

以晋城市的GDP核算工作为例,分析了地区性生产总值核算中存在的问题,并提出了改进地区生产总值核算的对策。