Unravelling the signal-transduction network in B lymphocytes

The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large.     

嵌入式系统实践教学研究与设计

为培养适应社会需求的嵌入式人才,本文提出符合计算机专业特点的嵌入式软件技术方向人才培养目标,对目前计算机嵌入式系统教学的现状展开分析与研究,结合嵌入式实验教学的特点,制定了一套切实可行的课程体系和教学模式,包括设计多层次嵌入式实验内容,实践开发平台,WinCE开发工具以及教学考核方式等多方面的内容。     

Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice.

The inhibins are alpha:beta heterodimeric growth factors that are members of the transforming growth factor-beta family. To understand the physiological roles of the inhibins in mammalian development and reproduction, a targeted deletion of the alpha-inhibin gene was generated by homologous recombination in mouse embryonic stem cells. Mice homozygous for the null allele (inhibin-deficient) initially develop normally but every mouse ultimately develops mixed or incompletely differentiated gonadal stromal tumours either unilaterally or bilaterally. Inhibin is thus a critical negative regulator of gonadal stromal cell proliferation and the first secreted protein identified to have tumour-suppressor activity.