烷基取代膦酸二甲酯的合成与表征

以溴戊烷、溴己烷、1,2-二溴乙烷和亚磷酸三甲酯为原料,分别合成了戊基、己基、溴乙基取代的三种膦酸二甲酯化合物.并报道了所合成的化合物的红外光谱、核磁共振氢谱及核磁共振碳谱的数据.     

自体富血小板血浆治疗下肢慢性创伤及骨不连的研究

Patients with chronic wounds frequently undergo repetitive debridement without a definitive outcome because of the scarcity of growth factors. Platelet-rich plasma (PRP) has been shown to enhance tissue healing with multiple growth factors. We evaluated the clinical effects of PRP in the treatment of chronic wounds. Seventeen patients with chronic wounds on the lower limbs were treated with the application of autologous PRP twice at a 2-month interval to close the wound and control infection. We found that the average volume of the chronic wounds significantly decreased. In addition, 10 of the 17 patients had complete wound coverage and another 6 patients had >50% wound coverage. Fracture reunion was also observed in 6 of the 10 patients with complete wound coverage. PRP treatment also dramatically reduced the positive results of bacterial culture, from 82.4% to 11.8%. Therefore, we concluded that PRP treatment can efficiently facilitate chronic wound healing and be considered an effective treatment during the management of some complicated chronic wounds.     

杯芳烃对有机小分子识别作用的研究进展

简要综述了近年来杯芳烃识别有机小分子的研究进展，主要涉及以非共价键作用发生的包结及作用方式。     

对[(对叔丁基苯基)-偶氮基]杯[4]芳烃的合成

以杯[4]芳烃和对叔丁基苯胺为原料,经重氮化-偶合反应,合成了对[(对叔丁基苯基)-偶氮基]杯[4]芳烃,通过IR,~1HNMR对其结构进行了表征,并对其性质进行了初步研究.     

25,26,27-三甲氧基-28-羟基杯[4]芳烃的合成

以硫酸二甲酯为烷基化试剂与杯 [4 ]芳烃反应 ,合成了 2 5 ,2 6 ,2 7 三甲氧基 2 8 羟基杯 [4 ]芳烃 ,通过1HNMR和IR对其结构进行了表征 .在所选合成条件下 ,标题化合物的最高收率可达 6 2 % .