SAm级防撞活动护栏碰撞仿真分析

针对目前高速公路中央分隔带开口处活动护栏防撞等级较低的问题,提出了一种SAm级混凝土活动护栏及一种新型连接装置。基于有限元的方法,建立车辆与护栏的碰撞模型,通过LS-DYNA对车辆与护栏碰撞过程进行求解,根据不同车型的碰撞结果分别在缓冲,阻挡和导向性能上对护栏的安全性能进行评价,其中小型车辆与护栏碰撞后的OIV(Occupant Impact Velocity)值<12 m/s,ORA(Occupant Ridedown Acceleration)值<20 g且车辆没有驶出导向框;大型车辆与护栏碰撞后没有发生穿越、骑跨等现象且车辆没有驶出导向框,均满足护栏安全性能评价标准。     

论图书馆人力资源的开发与管理

本文阐述了人力资源在图书馆事业发展中的特殊作用，并针对图书馆人力资源管理的现状，论述了开发与管理的对策。     

电负性及其在无机化学上的应用

从用电负性来衡量元素在化合物分子中吸引电子的能力的必要性出发，阐述电负性的概念以及阿莱－罗周（Ａｌｌｒｅｄ－Ｒｏｃｈｏｗ）计算电负性标的方法，重点论述了电负性在无机化学上的某些应用．     

集成系统中工艺卡片填写与工序图绘制的研究

利用VBA实现CAD和CAPP系统集成，讨论了基于Word平台进行工艺卡填写，并在此基础上进行工艺卡填写和工序图并行输出的一般问题。工艺文件的填写是在CAPP数据库的支持下，直接读取CAD所提供的CAPP工艺数据文件，经推理机推理自动生产工艺过程；工序图绘制是在特征图表级和参数化绘图原理的基础上进行的。     

视图中插入文本块的编程方法

在一般应用软件中，文本输入是必不可少的。如何让文本输入像画线、画圆、画椭圆一样简单方便，实现在视图中插入文本块？可将输入的文本看成是一个文本块，或者说是一个矩形，在矩形中完成文本的输入、修改、换行等操作。这样，工作就转化为在视图中插入一个矩形，编程并让该矩形响应鼠标和键盘消息，从而实现文本块中文本的输入及各项操作。具体通过VC＋＋中文档、视图之间数据交换和各自职能的特点以及C＋＋中面向对象的技术^[1,2]，实现了在视图中插入文本块的方法。这里的文本块如其它的图形对象一样，可以选择、可以移动、可以修改、可以删除。最后给出了实现结果的图片。     

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast

The autosomal recessive disorder Shwachman-Diamond syndrome, characterized by bone marrow failure and leukemia predisposition, is caused by deficiency of the highly conserved Shwachman-Bodian-Diamond syndrome (SBDS) protein. Here, we identify the function of the yeast SBDS ortholog Sdo1, showing that it is critical for the release and recycling of the nucleolar shuttling factor Tif6 from pre-60S ribosomes, a key step in 60S maturation and translational activation of ribosomes. Using genome-wide synthetic genetic array mapping, we identified multiple TIF6 gain-of-function alleles that suppressed the pre-60S nuclear export defects and cytoplasmic mislocalization of Tif6 observed in sdo1Delta cells. Sdo1 appears to function within a pathway containing elongation factor-like 1, and together they control translational activation of ribosomes. Thus, our data link defective late 60S ribosomal subunit maturation to an inherited bone marrow failure syndrome associated with leukemia predisposition.     

Sul meccanismo di azione della streptomicina

Summary A study was undertaken on the variations of the redox potential level produced by streptomycinin vitro andin vivo. We have been able to show that, owing to an oxidative effect, streptomycin produces an increase of the redox potential level. This oxidative effect varies in degree according to the condition of the patient.We also found that in the blood and in the spinal fluid of patients suffering from tubercular meningitis factors are present which inhibit the action of streptomycin.The results of our findings lead to the conclusion that the dose of streptomycin must be varied according to the condition of the patient if the constant level required for an efficient therapy is to be maintained in the blood and in the spinal fluid.     

Kondensationsprodukte von Oxyketonen und Aminoketonen mit 2,4,5-Triamino-6-oxy-pyrimidin

Summary By condensing 2:4:5-triamino-6-hydroxy-pyrimidine with dihydroxyacetone (diacetate), diaminoacetone or acetone-1,3-di (p-formylaminobenzoic acid) not the expected 8- or 9-oxymethyl resp. -aminomethyl-pteridines but 8-or 9-methyl-pteridines were obtained. With p-tolyl-d-isoglucosamine not a tetrahydroxybutyl-pteridine but a trihydroxybutyl-pteridine was formed. For an explanation of these results it is supposed that from the dihydro-pteridines formed at first by intramolecular splitting off of H₂O or R·NH₂ aromatization takes place.