排序方式: 共有3条查询结果,搜索用时 15 毫秒
1
1.
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility 总被引:14,自引:0,他引:14
Parkes M Barrett JC Prescott NJ Tremelling M Anderson CA Fisher SA Roberts RG Nimmo ER Cummings FR Soars D Drummond H Lees CW Khawaja SA Bagnall R Burke DA Todhunter CE Ahmad T Onnie CM McArdle W Strachan D Bethel G Bryan C Lewis CM Deloukas P Forbes A Sanderson J Jewell DP Satsangi J Mansfield JC;Wellcome Trust Case Control Consortium Cardon L Mathew CG 《Nature genetics》2007,39(7):830-832
A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs from these and other loci for association in an independent case-control sample. We obtained replication for the autophagy-inducing IRGM gene on chromosome 5q33.1 (replication P = 6.6 x 10(-4), combined P = 2.1 x 10(-10)) and for nine other loci, including NKX2-3, PTPN2 and gene deserts on chromosomes 1q and 5p13. 相似文献
2.
大连市银杏叶斑病病原菌鉴定 总被引:1,自引:0,他引:1
银杏(Ginkgo biloba L.)是常见的城市园林观赏绿化树种,并具有极高的材用、食用和药用价值.近年来,大连市银杏树发生了一种不明病因且较为严重的叶斑病,查明病因、为病害防治提供理论依据迫在眉睫.从病害发生严重区域采集叶斑病病叶样本,采用感病叶片单斑分离法,对分离菌株进行致病性测定、形态学鉴定及分子生物学鉴定等,对大连市银杏树发生的叶斑病进行了病原菌鉴定.结果表明,大连银杏叶斑病致病菌有2种,分别为链格孢属细极链格孢(Alternaria tenuissima)和链格孢(Alternaria alternata).迄今为止,细极链格孢(Alternaria tenuissima)侵染银杏导致其发生叶斑病鲜有报道. 相似文献
3.
1