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G. P. Fantin D. Bottecchia P. Gruppo G. Nassuato M. Barbera 《Cellular and molecular life sciences : CMLS》1978,34(5):661-662
Summary It was demonstrated that the previous in vitro electrical stimulation of human and rat platelet-rich plasma does not modify the subsequent response of platelets to the aggregating activity of ADP, thrombin, thrombofax or adrenaline. This is interesting in view of the fact that the electrical stimulation can induce clot retraction.Acknowledgments. We thank Mr Renzo Ferronato for his technical assistance and Miss Maria Tommasini for her secretarial aid. 相似文献
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It was demonstrated that the previous in vitro electrical stimulation of human and rat platelet-rich plasma does not modify the subsequent response of platelets to the aggregating activity of ADP, thrombin, thrombofax or adrenaline. This is interesting in view of the fact that the electrical stimulation can induce clot retraction. 相似文献
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L. Bolognani A. M. Bolognani Fantin R. Lusignani L. Zonta 《Cellular and molecular life sciences : CMLS》1966,22(9):601-603
Riassunto Sono stati studiati con analisi biochimiche gli involucri ovulari diR. latastei eB. vulgaris, soprattutto in relazione alla presenza di esosamine e acidi sialici. Sono presenti sia glucosamina che galattosamina con un rapporto inR. latastei di 11,3 e inB. vulgaris di 18,8. Gli acidi sialici sono contenuti in quantità elevata cosî pure il glucosio, mentre sono assenti acido glucuronico e SO4
––. Si è potuto quindi concludere che negli involucri ovulari delle due specie considerate sono presenti sialofucopolisaccaridi con quantità variabili di esosamine. 相似文献
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Summary Splenectomy completely erased the PFC response to SRBC in lizards. In contrast, it has very little effect on the degree of MI to all doses ranging from 104 to 109, excepting the lowest dose, 103 SRBC.Supported by PL-480 (NIH) research grant, No. 01-077.Grateful to Madurai University for the award of Studentship during the tenure of the work and to Dr P. W. Askenase for the gift of capillaries used in this study. 相似文献
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Amary MF Damato S Halai D Eskandarpour M Berisha F Bonar F McCarthy S Fantin VR Straley KS Lobo S Aston W Green CL Gale RE Tirabosco R Futreal A Campbell P Presneau N Flanagan AM 《Nature genetics》2011,43(12):1262-1265
Ollier disease and Maffucci syndrome are characterized by multiple central cartilaginous tumors that are accompanied by soft tissue hemangiomas in Maffucci syndrome. We show that in 37 of 40 individuals with these syndromes, at least one tumor has a mutation in isocitrate dehydrogenase 1 (IDH1) or in IDH2, 65% of which result in a R132C substitution in the protein. In 18 of 19 individuals with more than one tumor analyzed, all tumors from a given individual shared the same IDH1 mutation affecting Arg132. In 2 of 12 subjects, a low level of mutated DNA was identified in non-neoplastic tissue. The levels of the metabolite 2HG were measured in a series of central cartilaginous and vascular tumors, including samples from syndromic and nonsyndromic subjects, and these levels correlated strongly with the presence of IDH1 mutations. The findings are compatible with a model in which IDH1 or IDH2 mutations represent early post-zygotic occurrences in individuals with these syndromes. 相似文献
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Effect of manganese on the ADP-induced platelet aggregation 总被引:1,自引:0,他引:1
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D. Bottecchia G. P. Fantin P. Gruppo G. Nassuato M. Barbera 《Cellular and molecular life sciences : CMLS》1977,33(11):1527-1529
Summary the spontaneous clot retraction of platelet-rich plasma is inhibited by previous in vitro ADP-induced platelet aggregation. The electrical stimulation of the clot always restores a maximal clot retraction, even after a prolonged previous in vitro platelet aggregation.Acknowledgment. We thank Mr Renzo Ferronato for his technical assistance and Miss Maria Tommasini for her secretarial aid. 相似文献
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